|1.||Mutreja, Karun: 1 article (03/2015)|
|2.||Lopes, Massimo: 1 article (03/2015)|
|3.||Schmid, Jonas A: 1 article (03/2015)|
|4.||Zellweger, Ralph: 1 article (03/2015)|
|5.||Vindigni, Alessandro: 1 article (03/2015)|
|6.||Berti, Matteo: 1 article (03/2015)|
|7.||Dalcher, Damian: 1 article (03/2015)|
|8.||Herrador, Raquel: 1 article (03/2015)|
|9.||Tsurita, Giichiro: 1 article (11/2014)|
|10.||Imai, Kohzoh: 1 article (11/2014)|
01/01/1997 - "Therapeutic dose and timing of administration of RNA synthesis inhibitors for preventing cerebral vasospasm after subarachnoid hemorrhage."
01/01/1997 - "once) prevented vasospasm even though the treatment started on Day 4. The present study suggests that RNA synthesis inhibitors, such as dactinomycin and doxorubicin, may aufficiently prevent or ameliorate cerebral vasospasm in severe SAH patients."
|2.||Retinoblastoma (Glioblastoma, Retinal)
04/01/1994 - "RNA synthesis inhibitors increase melatonin production in Y79 human retinoblastoma cells."
04/01/1994 - "We have extended these studies to investigate the role of RNA synthesis in melatonin regulation, and report here that RNA synthesis inhibitors do not suppress melatonin production in Y79 retinoblastoma cells. "
09/01/2008 - "DNA synthesis inhibitors and damaging agents are widely used in cancer therapy; however, sensitivity of tumors to such agents is highly variable. "
01/01/1984 - "The effects of protein and DNA synthesis inhibitors on in vitro tumor cell invasion was studied in a quantitative invasion system using human amnion. "
09/01/1999 - "As repair inhibitors, they have the potential to increase the amount of residual DNA and chromosome damage after irradiation, and as DNA synthesis inhibitors, they specifically target the S-phase cell component and could thus overcome the detrimental effect of tumor clonogen repopulation during fractionated irradiation. "
02/01/1990 - "Androgen-responsive S115+A mouse mammary tumor cells were mutagenized with ethyl methane sulfonate and the variants which were growth-arrested in suspension at the nonpermissive temperature of 41 degrees C were selected by killing dividing wild-type cells with the DNA synthesis inhibitors 5-fluoro-2'-deoxyuridine or cytosine arabinoside. "
04/25/1982 - "Effects of methotrexate on ribonucleotide pools in growing and in growth-arrested tumor cells and antagonism by RNA synthesis inhibitors."
05/01/2013 - "Because of the cycles of reactivation from a latent state, much emphasis has been placed on the management of infection through the use of DNA synthesis inhibitors. "
07/01/2002 - "Reporter activity was readily assayed in vivo during acute infection and reactivation from latency and was also sensitive to DNA synthesis inhibitors. "
05/01/1972 - "[Effects of protein and DNA synthesis inhibitors on ectromelia infection]."
12/01/1990 - "Analysis of time course experiments and experiments using DNA synthesis inhibitors demonstrated that the UL37 protein is expressed prior to the onset of viral DNA synthesis, reaching maximum levels late in infection, classifying it as a gamma 1 gene. "
01/01/1983 - "Effects of DNA synthesis inhibitors on early antigen expression following primary infection or superinfection by Epstein-Barr virus."
|5.||Hepatocellular Carcinoma (Hepatoma)
10/01/1999 - "The expression of the asialoglycoprotein receptor (ASGP-R) on human hepatocellular carcinoma (HCC) cells might be exploited to reduce the extrahepatic toxicity of DNA synthesis inhibitors by their conjugation with galactosyl-terminating peptides. "
10/01/1982 - "As an indirect test of the possibility that cyclic AMP produces its stimulatory effects on the synthesis of tyrosine aminotransferase (L-tyrosine:2-oxoglutarate aminotransferase, EC 220.127.116.11) by stabilizing its mRNA, the kinetics of decline in the rate of synthesis of this enzyme was measured in rat hepatoma cells following inducer removal or addition of RNA synthesis inhibitors. "
|1.||RNA (Ribonucleic Acid)
|5.||DNA (Deoxyribonucleic Acid)
|10.||Telomerase (Telomerase Reverse Transcriptase)
|2.||Drug Therapy (Chemotherapy)