|1.||Driessens, Gregory: 1 article (02/2011)|
|2.||Nuttin, Lise: 1 article (02/2011)|
|3.||Mievis, Stephane: 1 article (02/2011)|
|4.||Préat, Véronique: 1 article (02/2011)|
|5.||Maetens, Julie: 1 article (02/2011)|
|6.||Velu, Thierry: 1 article (02/2011)|
|7.||Bruyns, Catherine: 1 article (02/2011)|
|8.||Gras, Alain: 1 article (02/2011)|
|9.||Tenenbaum, Liliane: 1 article (02/2011)|
|10.||Schoore, Marylène: 1 article (02/2011)|
02/01/2011 - "To bypass this limitation possibly due to the short half-life of recombinant GM-CSF, we have generated adeno-associated virus coding for mGM-CSF and tested their efficacy to transduce tumor cells in vitro and in vivo. "
09/01/1999 - "Sequential administration of escalating doses of a GM-CSF recombinant vaccinia virus is safe, effective at maintaining passenger gene function, and can induce tumor regression."
01/20/1997 - "These data suggest that transduction of tumor cells with recombinant GM-CSF adenovirus may be an effective and practical cancer gene therapeutic strategy."
03/15/2007 - "In a previous study, we observed minimal therapeutic impact, but significantly enhanced T cell cross-priming and lesional infiltration of tumor-reactive CD8+ T cells into established CMS4 sarcomas after combined treatment of BALB/c mice with rFLt3 ligand (rFL) and recombinant GM-CSF (rGM-CSF). "
05/01/2006 - "Recombinant GM-CSF plus autologous tumor cells as a vaccine for patients with mesothelioma."
|3.||Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
06/01/1998 - "Recombinant GM-CSF has been recently shown to prolong survival of elderly patients with acute myeloid leukemia (AML) by reducing the rate of induction therapy-related mortality. "
07/01/1986 - "Effects of recombinant GM-CSF on the blast cells of acute myeloblastic leukemia."
07/01/1993 - "The effect of human recombinant GM-CSF (rGM-CSF) on the metabolism of high dose ara-C was determined in bone marrow mononuclear cells (BMMCs) from eight normal volunteers and from seven patients with acute myelogenous leukemia (AML). "
01/01/1989 - "Effect of recombinant GM-CSF and recombinant G-CSF on colony formation of blast progenitors in acute myeloblastic leukemia."
01/01/1990 - "We studied the effect of preincubation with recombinant GM-CSF on the activity of cytarabine and doxorubicin against clonogenic acute myeloid leukemia cells (CFU-AML). "
|4.||Neoplasm Metastasis (Metastasis)
08/01/2001 - "Seven patients with histologically confirmed cutaneous melanoma metastases were treated with perilesional intracutaneous injections of recombinant GM-CSF and observed for a follow-up time of 5 y. "
09/01/1999 - "Seven immunocompetent, revaccinated patients with surgically incurable cutaneous melanoma underwent treatment of dermal and/or subcutaneous metastases with twice-weekly intratumoral injections of escalating doses (10(4)-2 x 10(7) plaque-forming units (PFU)/lesion; 10(4)-8 x 10(7) PFU/session) of a vaccinia/GM-CSF recombinant virus for 6 weeks. "
02/20/1993 - "In the present study, pre-incubation of LLC-LN7 cells with neutralizing anti-GM-CSF antibodies diminished the capacity of the tumor cells to form experimental metastases after i.v. inoculation, while pre-incubation with recombinant GM-CSF (rGM-CSF) increased formation of metastases. "
|5.||Myelodysplastic Syndromes (Myelodysplastic Syndrome)
12/01/1988 - "Recombinant GM-CSF effectively restores granulopoiesis in AIDS patients and appears capable of improving myelopoiesis and, in some cases, erythropoiesis in subjects with myelodysplastic syndrome. "
01/01/2001 - "Phase II study of combination human recombinant GM-CSF with intermediate-dose cytarabine and mitoxantrone chemotherapy in patients with high-risk myelodysplastic syndromes (RAEB, RAEBT, and CMML): an Eastern Cooperative Oncology Group Study."
|2.||Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)
|8.||Etoposide (VP 16)
|9.||DNA (Deoxyribonucleic Acid)
|1.||Drug Therapy (Chemotherapy)
|3.||Bone Marrow Transplantation (Transplantation, Bone Marrow)
|5.||Heterologous Transplantation (Xenotransplantation)