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12-Hydroxy-5,8,10,14-eicosatetraenoic Acid

A lipoxygenase metabolite of ARACHIDONIC ACID. It is a highly selective ligand used to label mu-opioid receptors in both membranes and tissue sections. The 12-S-HETE analog has been reported to augment tumor cell metastatic potential through activation of protein kinase C. (J Pharmacol Exp Ther 1995; 274(3):1545-51; J Natl Cancer Inst 1994; 86(15):1145-51)
Also Known As:
12 S Hydroxyeicosatetraenoic Acid; Acid, 12-S-Hydroxyeicosatetraenoic; 12-HETE; 12-R-HETE; 12-S-HETE; 12-S-Hydroxyeicosatetraenoic Acid
Networked: 108 relevant articles (1 outcomes, 5 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Yang, Peiying: 2 articles (10/2012 - 10/2007)
2. Newman, Robert A: 2 articles (10/2012 - 10/2007)
3. Kudva, Shobha: 1 article (10/2015)
4. Pilkington, Suzanne M: 1 article (10/2015)
5. Rhodes, Lesley E: 1 article (10/2015)
6. Nicolaou, Anna: 1 article (10/2015)
7. Murphy, Sharon A: 1 article (10/2015)
8. Mano, Nariyasu: 1 article (07/2015)
9. Furugen, Ayako: 1 article (07/2015)
10. Yamaguchi, Hiroaki: 1 article (07/2015)

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