Sodium Lactate

03/25/2014 - "Infusion of half-molar sodium lactate improved cardiac performance and led to metabolic alkalosis in AHF patients without any detrimental effects on organ function. "
11/01/1986 - "Alkalosis is prominent among the many physiologic and biochemical effects of sodium lactate infusion. "
06/01/1985 - "The metabolic response of the kidney to acute sodium lactate alkalosis."
07/07/2014 - "Further studies are needed to establish the most appropriate dose and indications for sodium lactate infusion in order to prevent the occurrence of severe hypernatremia and metabolic alkalosis."
07/01/1996 - "Sodium lactate as a metabolic substrate limits hyperglycemia but induces metabolic alkalosis and does not spare the ventilatory demand."

09/01/2003 - "Beginning with the study of Pitts and McClure, who described the panicogenic activity of sodium lactate, the experimental induction of panic attacks with different challenges has been used to characterize the neurobiology of anxiety. "
03/01/2001 - "In the present study we tested this hypothesis by evaluating the effect of sodium lactate on this aggressiveness, because this substance is recognized to induce spontaneous panic attacks in patients. "
01/01/1996 - "We have undertaken studies of panic disorder using MRS to investigate acute panic precipitated by physiological or chemical challanges, such as intravenous sodium lactate infusion, while measuring brain metabolic responses. "
02/01/1995 - "The authors used the family study method to test the hypothesis that sodium lactate response defines two subtypes of panic disorder. "
01/01/1994 - "This study investigated the frequency and severity of symptoms during naturally occurring panic attacks recollected as "usual" and during sodium lactate-induced attacks. "

08/14/2014 - "In our hypodynamic model of endotoxic shock, infusion of hypertonic sodium lactate improves hemodynamic and microvascular reactivity with a negative fluid balance and a better oxygenation."
08/14/2014 - "Based on the potential interest in sodium lactate as an energy substrate and resuscitative fluid, we investigated the effects of hypertonic sodium lactate in a porcine endotoxic shock. "
08/14/2014 - "Hypertonic sodium lactate improves fluid balance and hemodynamics in porcine endotoxic shock."
12/01/2014 - "The results not only suggest unimpaired lactate metabolism during shock in children but document improvement in endothelial barrier function, limited coagulopathy, and avoidance of fluid overload with hypertonic sodium lactate. "
05/01/1981 - "A conclusion is made that the therapeutic effect of lactasol depends on the amount of the saline injected and on the period of shock during which the saline is injected, as well as on the specific action of sodium lactate."

09/01/1960 - "[The effect of sodium lactate in acidosic hyperkalemia]."
01/01/1960 - "A comparative analysis of molar sodium lactate and other agents in the treatment of induced hyperkalemia in nephrectomized dogs."
10/01/1957 - "The effects of molar sodium lactate in reversing the cardiotoxic effect of hyperpotassemia."
10/01/1966 - "[The place of molar sodium lactate in the emergency treatment of acute postoperative hyperkalemia]."
11/01/2011 - "This study assessed the safety and efficacy of a potassium cocktail (k-cocktail) containing dextrose, insulin, calcium gluconate, and sodium lactate for treatment of neonatal hyperkalemia. "

01/01/2022 - "Molar sodium lactate was effective in limiting the severity of the postcardiac arrest syndrome. "
01/01/2022 - "Molar Sodium Lactate Attenuates the Severity of Postcardiac Arrest Syndrome: A Preclinical Study."