|1.||Reynolds, C P: 4 articles (01/2014 - 12/2000)|
|2.||Reynolds, C Patrick: 3 articles (10/2015 - 04/2003)|
|3.||Savarino, Andrea: 3 articles (10/2015 - 01/2009)|
|4.||Rodríguez-Gómez, Isabel: 3 articles (08/2014 - 08/2010)|
|5.||Wangensteen, Rosemary: 3 articles (08/2014 - 08/2010)|
|6.||Vargas, Félix: 3 articles (08/2014 - 08/2010)|
|7.||Lokhandwala, Mustafa F: 3 articles (08/2011 - 09/2008)|
|8.||Park, Woo Hyun: 3 articles (08/2010 - 08/2008)|
|9.||Jordan, V Craig: 3 articles (03/2009 - 01/2008)|
|10.||Lewis-Wambi, Joan S: 3 articles (03/2009 - 01/2008)|
07/15/2009 - "The synergistic effects observed from the combination of X-rays plus 2-AAPA were comparable to those from the combination of X-rays plus buthionine sulfoximine, a reference compound known to increase cancer sensitivity to radiation. "
09/01/1992 - "However, by buthionine sulfoximine treatment, the toxicity of multidrug resistant Sa 180 tumors could be increased. "
05/01/1989 - "To deplete tumor GSH, buthionine sulfoximine (BSO) was administered in the animals drinking water (10 mM) following two i.p. "
12/01/1989 - "Subcutaneous injection(s) of buthionine sulfoximine (BSO) significantly depleted the GSH content in the tumor and organs. "
07/01/2004 - "Effective treatment of advanced solid tumors by the combination of arsenic trioxide and L-buthionine-sulfoximine."
02/01/2015 - "Oxovanadium-based inhibitors can drive redox-sensitive cytotoxicity in neuroblastoma cells and synergise strongly with buthionine sulfoximine."
05/05/2014 - "Exposure of human neuroblastoma SH-SY5Y cells to 1,2-NQ after pretreatment with buthionine sulfoximine (BSO) to deplete GSH resulted in an enhancement of covalent modification of UCH-L1 by 1,2-NQ. "
07/01/2011 - "Thus, we investigated whether VKs also have protective effects against GSH-depletion-induced cell death by employing two GSH reducers, L-buthionine sulfoximine (BSO) and diethyl maleate (DEM), in primary cultured neurons and human neuroblastoma IMR-32 cells. "
10/01/2015 - "Pilot study of intravenous melphalan combined with continuous infusion L-S,R-buthionine sulfoximine for children with recurrent neuroblastoma."
04/01/2011 - "In this report, we show that, in neuroblastoma cells as well as in primary mouse cortical neurons, GSH decrease, induced by buthionine sulfoximine (BSO), causes protein nitration, S-nitrosylation and DNA strand breaks. "
10/01/1996 - "Modifications in lens protein biosynthesis signal the initiation of cataracts induced by buthionine sulfoximine in mice."
01/01/1996 - "In order to develop a more adequate ultraviolet (UV)-induced cataract model, a combination of l-buthionine sulfoximine (BSO) treatment was applied to experimental animals. "
01/01/1996 - "UV-b-induced cataract model in brown-Norway rat eyes combined with preadministration of buthionine sulfoximine."
04/01/1992 - "Lens GSH depletion and electrolyte changes preceding cataracts induced by buthionine sulfoximine in suckling mice."
11/01/1989 - "Relatively low doses of buthionine sulfoximine produce cataracts in newborn animals, and treatment of pregnant mice with buthionine sulfoximine during the last part of gestation leads to cataract formation in the offspring. "
04/01/1993 - "Effect of L-buthionine sulfoximine on the radiation response of human renal carcinoma cell lines."
07/01/1986 - "The effect of L-buthionine sulfoximine on the aerobic radiation response of A549 human lung carcinoma cells."
08/01/1984 - "Many investigators have observed aerobic sensitization of V79, CHO and A549 (human lung carcinoma) cells upon depletion of GSH using buthionine sulfoximine (BSO). "
09/14/2011 - "Preclinical evaluation of azathioprine plus buthionine sulfoximine in the treatment of human hepatocarcinoma and colon carcinoma."
01/01/2003 - "Glutathione depletion by L-buthionine sulfoximine inhibits the growth of Ehrlich mouse mammary carcinoma, R3230Ac rat mammary carcinoma and the PC3 human prostrate carcinoma cells, in vitro. "
|5.||Wounds and Injuries (Trauma)
06/10/2006 - "This study investigated in vivo protective effects of LQ against acute liver injuries induced by acetaminophen (APAP) or APAP plus buthionine sulfoximine (BSO). "
06/10/2006 - "Liquiritigenin, an aglycone of liquiritin in Glycyrrhizae radix, prevents acute liver injuries in rats induced by acetaminophen with or without buthionine sulfoximine."
|1.||Glutathione (Reduced Glutathione)
|3.||Thioctic Acid (Lipoic Acid)
|8.||arsenic trioxide (Trisenox)
|9.||Reactive Oxygen Species (Oxygen Radicals)
|1.||Heterologous Transplantation (Xenotransplantation)
|2.||Drug Therapy (Chemotherapy)