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BRCA1 Protein

The phosphoprotein encoded by the BRCA1 gene (GENE, BRCA1). In normal cells the BRCA1 protein is localized in the nucleus, whereas in the majority of breast cancer cell lines and in malignant pleural effusions from breast cancer patients, it is localized mainly in the cytoplasm. (Science 1995;270(5237):713,789-91)
Also Known As:
Breast Cancer 1 Protein; BRCA1 Gene Product; Breast Cancer 1 Gene Product
Networked: 148 relevant articles (1 outcomes, 17 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Parvin, Jeffrey D: 4 articles (03/2013 - 06/2004)
2. Swisher, Elizabeth M: 3 articles (03/2013 - 04/2008)
3. Taniguchi, Toshiyasu: 3 articles (03/2013 - 04/2008)
4. Chambon, Monique: 3 articles (01/2013 - 05/2003)
5. Rosen, Eliot M: 3 articles (01/2013 - 01/2003)
6. Monteiro, Alvaro N A: 3 articles (06/2010 - 06/2004)
7. Goldberg, I D: 3 articles (08/2001 - 01/2001)
8. Rosen, E M: 3 articles (08/2001 - 01/2001)
9. Privat, Maud: 2 articles (11/2014 - 06/2010)
10. Troudi, Wafa: 2 articles (11/2014 - 07/2007)

Related Diseases

1. Ovarian Neoplasms (Ovarian Cancer)
2. Breast Neoplasms (Breast Cancer)
3. Neoplasms (Cancer)
4. Carcinoma (Carcinomatosis)
5. Genomic Instability

Related Drugs and Biologics

1. Proteins (Proteins, Gene)
2. PPAR gamma
3. Protein Isoforms (Isoforms)
4. Complementary DNA (cDNA)
5. Biological Markers (Surrogate Marker)
6. Ribonucleases (Ribonuclease)
7. Ligands
8. Estrogens (Estrogen)
9. Agar
10. rosiglitazone (Avandia)

Related Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Combination Drug Therapy (Combination Chemotherapy)