|1.||Aquino, Angelo: 4 articles (11/2010 - 04/2002)|
|2.||Bonmassar, Enzo: 4 articles (11/2010 - 04/2002)|
|3.||Liu, Dong: 4 articles (05/2008 - 03/2002)|
|4.||Jantas, Danuta: 3 articles (12/2015 - 07/2007)|
|5.||Jantas, D: 3 articles (09/2015 - 03/2008)|
|6.||Lason, W: 3 articles (09/2015 - 03/2008)|
|7.||Leskiewicz, M: 3 articles (09/2015 - 03/2008)|
|8.||Barry, Michele: 3 articles (01/2015 - 11/2002)|
|9.||Zha, Xiliang: 3 articles (08/2013 - 01/2009)|
|10.||Yao, Wantong: 3 articles (08/2013 - 01/2009)|
09/01/2011 - "Since staurosporine derivatives have proven efficacy in clinical trials, activation of this novel pathway might represent a powerful target to induce apoptosis in multidrug-resistant tumor cells."
07/15/2015 - "Anti-tumor activity of staurosporine in the tumor microenvironment of cervical cancer: An in vitro study."
01/01/2011 - "In this study, we found that when various cancer cell lines (HeLa, MCF-7, and 293T) stably expressing fLuc were treated with staurosporine (STS), there was a rapid loss in bioluminescence. "
08/23/2002 - "The results presented in this study show that p57(Kip2) has a stimulatory effect on apoptosis induced by staurosporine, suggesting a role for p57(Kip2) in the response of tumor cells to cytotoxic drugs."
03/08/2001 - "These distinct features of staurosporine may allow to bypass chemoresistance of tumor cells and may encourage further clinical trials for the use of staurosporine derivatives in antitumor therapy."
01/01/2013 - "In vitro, DXS bound human myoblasts in a dose-dependent manner and significantly inhibited staurosporine-mediated apoptosis and necrosis. "
12/01/2010 - "In particular, exposure to H(2)O(2) or staurosporine showed the largest number of myoblasts in late apoptotic stages and in secondary necrosis. "
01/01/2006 - "Aspergillus fumigatus conidia inhibit tumour necrosis factor- or staurosporine-induced apoptosis in epithelial cells."
05/01/2004 - "Moreover, both molecular and cellular read-outs indicated that staurosporine-induced cell death was necrosis rather than apoptosis in these cells. "
05/01/2004 - "Bcl2-low-expressing MCF7 cells undergo necrosis rather than apoptosis upon staurosporine treatment."
02/01/2006 - "The present work was focused on the study of the Epo protective effect upon human neuroblastoma SH-SY5Y cells subjected to differentiation by staurosporine. "
01/01/2004 - "In this study, we demonstrate a phase-specific resistance due to survivin in staurosporine (STS)-induced apoptosis in the human neuroblastoma cell line SK-N-MC. "
01/01/2002 - "In this study we have compared the efficiency and final outcome of three different anti-apoptotic strategies in staurosporine-treated SH-SY5Y human neuroblastoma cells. "
01/01/2013 - "In vitro cytoprotection assays showed that the asialo-rhuEPO(P) (20 U/ml) provides 2-fold better cytoprotection (44%) to neuronal-like mouse neuroblastoma cells from staurosporine-induced cell death than rhuEPO(M) (21%). "
12/01/2012 - "SH-SY5Y neuroblastoma cells differentiated to the cholinergic phenotype were exposed to 100nM staurosporine. "
05/01/1993 - "Staurosporine was more effective in decreasing the proliferation of three glioma cell lines compared to the non-glioma cell lines. "
04/01/2003 - "In the present study an adenovirus vector expressing p16 or p21 genes in human glioma cell lines was used to examine cell cycle regulation and cell death induced by staurosporine. "
05/01/1993 - "The purpose of this study was to determine whether 1) elevated PKC activity was also a characteristic of fast growing cell lines of non-glial origin, 2) the proliferation rate of non-glioma cell lines correlated with their PKC activity and 3) the proliferation of non-glioma cell lines could be inhibited by staurosporine, a relatively selective PKC inhibitor, which significantly attenuates the growth of glioma cells. "
01/01/2014 - "Staurosporine induced apoptosis rapidly downregulates TDP- 43 in glioma cells."
02/01/2008 - "By dynamically monitoring cell volume, we show that the induction of apoptosis, via activation of either the intrinsic or extrinsic pathways with staurosporine or TRAIL, respectively, resulted in a rapid AVD in D54-MG human glioma cells. "
01/15/2015 - "Here we demonstrate that expression of functional EVM025 is crucial to prevent apoptosis triggered by virus infection and staurosporine. "
05/03/2013 - "tarda infection in FG-9307 cells failed to protect the staurosporine-induced apoptosis. "
01/01/2012 - "Persistent infection protected HeLa cells from apoptosis when they were exposed to staurosporine. "
05/01/2009 - "Here, we investigate whether Rickettsia rickettsii-infected host endothelial cells resist the effects of staurosporine, a potent inducer of apoptosis, and we explore the mechanisms underlying the anti-apoptotic effect of infection. "
05/01/2009 - "Rickettsia rickettsii infection protects human microvascular endothelial cells against staurosporine-induced apoptosis by a cIAP(2)-independent mechanism."
|2.||Staphylococcal Protein A (A, Protein)
|3.||Glutamic Acid (Glutamate)
|5.||Protein Kinase C
|6.||Protein Kinases (Protein Kinase)
|7.||7-hydroxystaurosporine (UCN 01)
|10.||K 252 (K252a)
|1.||Combination Drug Therapy (Combination Chemotherapy)
|5.||Drug Therapy (Chemotherapy)