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Staurosporine

An indolocarbazole that is a potent PROTEIN KINASE C inhibitor which enhances cAMP-mediated responses in human neuroblastoma cells. (Biochem Biophys Res Commun 1995;214(3):1114-20)
Also Known As:
8,12-Epoxy-1H,8H-2,7b,12a-triazadibenzo(a,g)cyclonona(cde)trinden-1-one, 2,3,9,10,11,12-hexahydro-9-methoxy-8-methyl-10-(methylamino)-, (8alpha,9beta,10beta,12alpha)-(+)-
Networked: 810 relevant articles (24 outcomes, 87 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Aquino, Angelo: 4 articles (11/2010 - 04/2002)
2. Bonmassar, Enzo: 4 articles (11/2010 - 04/2002)
3. Liu, Dong: 4 articles (05/2008 - 03/2002)
4. Jantas, Danuta: 3 articles (12/2015 - 07/2007)
5. Jantas, D: 3 articles (09/2015 - 03/2008)
6. Lason, W: 3 articles (09/2015 - 03/2008)
7. Leskiewicz, M: 3 articles (09/2015 - 03/2008)
8. Barry, Michele: 3 articles (01/2015 - 11/2002)
9. Zha, Xiliang: 3 articles (08/2013 - 01/2009)
10. Yao, Wantong: 3 articles (08/2013 - 01/2009)

Related Diseases

1. Neoplasms (Cancer)
2. Necrosis
3. Neuroblastoma
4. Glioma (Gliomas)
5. Infection

Related Drugs and Biologics

1. Phosphotransferases (Kinase)
2. Staphylococcal Protein A (A, Protein)
3. Glutamic Acid (Glutamate)
4. Doxorubicin (Adriamycin)
5. Protein Kinase C
6. Protein Kinases (Protein Kinase)
7. 7-hydroxystaurosporine (UCN 01)
8. PKC412
9. Cisplatin (Platino)
10. K 252 (K252a)

Related Therapies and Procedures

1. Combination Drug Therapy (Combination Chemotherapy)
2. Oral Administration
3. Ligation
4. Aftercare (After-Treatment)
5. Drug Therapy (Chemotherapy)