|1.||Mansfield, Brian C: 12 articles (05/2015 - 04/2003)|
|2.||Chou, Janice Y: 11 articles (05/2015 - 06/2008)|
|3.||Pan, Chi-Jiunn: 9 articles (11/2012 - 12/2002)|
|4.||Jun, Hyun Sik: 6 articles (05/2015 - 06/2008)|
|5.||Annabi, Borhane: 6 articles (05/2010 - 01/2006)|
|6.||Chou, J Y: 4 articles (02/2007 - 11/2000)|
|7.||Chou, Janice Yang: 4 articles (11/2003 - 12/2002)|
|8.||Lee, Young Mok: 3 articles (05/2014 - 10/2010)|
|9.||Khosla, Chaitan: 3 articles (05/2010 - 02/2004)|
|10.||Chen, Shih-Yin: 3 articles (01/2009 - 07/2008)|
|1.||Glycogen Storage Disease (Glycogenosis)
01/01/2009 - "Structure-function study of the glucose-6-phosphate transporter, an eukaryotic antiporter deficient in glycogen storage disease type Ib."
11/01/1980 - "The contradictory data obtained in studies of type 1b glycogenosis would be explained by an anomeric preference for the capture of glucose-6-phosphate by hepatic microsomes. "
01/01/2014 - "Glycogen storage disease type 1b (GSD1b) is an inherited metabolic defect of glycogenolysis and gluconeogenesis due to mutations of the SLC37A4 gene and to defective transport of glucose-6-phosphate. "
01/01/2014 - "[A Chinese patient with glycogen storage disease type Ib caused by mutations in the glucose-6-phosphate translocase gene]."
12/01/2013 - "Glycogen storage disease type Ib (GSDIb) is caused by a deficiency in the glucose-6-phosphate transporter (G6PT), which leads to neutrophil dysfunction. "
05/01/2007 - "Muscular insulin resistance is frequently characterized by blunted increases in glucose-6-phosphate (G-6-P) reflecting impaired glucose transport/phosphorylation. "
07/01/2001 - "Low intracellular glucose and glucose-6-phosphate concentrations indicate that decreased glucose transport is mainly responsible for common insulin resistance. "
04/15/2003 - "Increased glucose cycling between glucose and glucose-6-phosphate is characteristic of insulin resistance and hyperglycemia seen with Type II diabetes. "
03/01/1998 - "The mechanism of insulin resistance in obesity was examined in ten obese (BMI 33 +/- 1 kg/m2) and nine lean (BMI 22 +/- 1 kg/m2) Caucasian women during a hyperglycemic-hyperinsulinemic clamp using 13C and 31P nuclear magnetic resonance (NMR) spectroscopy to measure rates of muscle glycogen synthesis and intramuscular glucose-6-phosphate (G-6-P) concentrations. "
02/01/2011 - "in type 2 diabetic patients and their first-degree relatives, insulin resistance (IR) is associated with impairment of insulin-stimulated myocellular glucose-6-phosphate (g6p) and unidirectional flux through ATP synthase (fATP), suggesting the presence of inherited abnormal mitochondrial oxidative fitness. "
05/01/2014 - "In this issue of Blood, Jun et al, through the study of neutrophils deficient in the glucose-6-phosphate transporter, describe a novel role for the peroxisome proliferator-activated receptor-γ (PPARG) pathway in the regulation of key neutrophil functions and link this to concomitant hypoxia-inducible factor (HIF) 1α stabilization."
05/01/2010 - "Novel roles in cell survival and metabolic adaptation to hypoxia have been ascribed to the microsomal glucose-6-phosphate translocase (G6PT). "
03/01/1991 - "Response to Anoxia in Rice and Wheat Seedlings: Changes in the pH of Intracellular Compartments, Glucose-6-Phosphate Level, and Metabolic Rate."
09/01/1977 - "Role of glucose-6-phosphate in cerebral dysfunction following hypoxia and hypotension."
03/01/2009 - "Given that MSCs can survive hypoxia and that the glucose-6-phosphate transporter (G6PT) provides metabolic control that contributes to MSC mobilization and survival, we investigated the effects of low oxygen (1.2% O(2)) exposure on G6PT gene expression. "
|4.||Hepatocellular Carcinoma (Hepatoma)
01/01/1964 - "[ON THE GLUCOSE-6-PHOSPHATE CONTENT IN NORMAL AND DIABETIC LIVERS AND HEPATOMAS IN RATS]."
11/01/1957 - "Glucose-6-phosphate utilization in hepatoma, regenerating and newborn rat liver, and in the liver of fed and fasted normal rats."
11/27/2003 - "In this study, the expression of a luciferase reporter gene under the control of the glucose-6-phosphate transporter gene promoter was examined in transiently transfected hepatoma cells. "
11/27/2003 - "The overexpression of Fox O1 stimulated the induction of glucose-6-phosphate transporter promoter activity by dexamethasone via nt -215/-209 in hepatoma cells. "
01/01/1977 - "[Activity of the enzymes of glucose-6-phosphate metabolism in the tissues of hepatomas with different growth rates]."
|5.||Type 2 Diabetes Mellitus (MODY)
06/01/1994 - "Muscle glucose-6-phosphate concentrations rose during hypoglycemia by a twofold greater increment in NIDDM (P < 0.01). "
05/01/1996 - "We concluded that during fructose administration: 1) gluconeogenesis is increased, but EGP remains constant in NIDDM, obese non-diabetic, and lean individuals; 2) in lean individuals, both an increased glucagonaemia and an enhanced supply of gluconeogenic precursors are required to increase EGP; this increase in EGP occurs without changes in the relative proportion of glucose 6-phosphate production from fructose and from other sources (i.e. "
05/01/1992 - "Apart from increased intramuscular basal glucose concentrations in NIDDM patients, no consistent differences were observed in free glucose and glucose-6-phosphate concentrations between the groups. "
04/01/1992 - "To assess the rate-limiting step in muscle glycogen synthesis in non-insulin-dependent diabetes mellitus (NIDDM), the concentration of glucose-6-phosphate (G6P) was measured by 31P nuclear magnetic resonance (NMR) during a hyperglycemic-hyperinsulinemic clamp. "
10/01/1986 - "Glycogen synthase assayed with 10 mM glucose 6-phosphate was decreased in NIDDM (1,335 +/- 131 pmol incorporated) compared with obese or control subjects (2,512 +/- 451 and 2,239 +/- 230 pmol incorporated, respectively, P less than 0.01)."
|1.||Glycogen Synthase (Synthase I)
|4.||Adenosine Triphosphate (ATP)
|7.||Proteins (Proteins, Gene)
|8.||DNA (Deoxyribonucleic Acid)
|9.||fructose-1,6-diphosphate (fructose 1,6-diphosphate)
|10.||Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))
|5.||Induced Hyperthermia (Thermotherapy)