Megestrol Acetate (Borea)

Subscribe to Selected New Research on Megestrol Acetate

535 relevant articles (68 outcomes, 180 trials/studies) found for this Drug

Description: Megestrol acetate is a progestogen with actions and uses similar to those of the progestogens in general. It also has anti-androgenic properties. It is given by mouth in the palliative treatment or as an adjunct to other therapy in endometrial carcinoma and in breast cancer. Megestrol acetate has been approved to treat anorexia and cachexia. (From Reynolds JEF(Ed): Martindale: The Extra Pharmacopoeia (electronic version). Micromedex, Inc, Englewood, CO, 1995)

Also Known As:

Borea; Megace; Apo-Megestrol; Apotex Brand of Megestrol Acetate; Bristol-Myers Brand of Megestrol Acetate; Bristol-Myers Squibb Brand of Megestrol Acetate; Lemery Brand of Megestrol Acetate; Lin-Megestrol; Linson Pharma Brand of Megestrol Acetate; Madaus Brand of Megestrol Acetate; Maygace; Megefren; Megestat; Megostat; Mestrel; Nu-Megestrol; Nu-Pharm Brand of Megestrol Acetate; Prasfarma Brand of Megestrol Acetate; Squibb Brand of Megestrol Acetate; Acetate, Megestrol; Apo Megestrol; ApoMegestrol; Bristol Myers Brand of Megestrol Acetate; Bristol Myers Squibb Brand of Megestrol Acetate; Lin Megestrol; LinMegestrol; Nu Megestrol; Nu Pharm Brand of Megestrol Acetate; NuMegestrol

Relationship Network

Drug Context: Research Results

Polycyclic Compounds: 58

Megestrol Acetate: 535

Experts

1.	Jatoi, Aminah: 4 articles (10/2006 - 01/2002)
2.	Evans, William J: 3 articles (02/2007 - 05/2002)
3.	Sloan, Jeff A: 3 articles (06/2004 - 01/2002)
4.	Novotny, Paul J: 3 articles (06/2004 - 01/2002)
5.	Mailliard, James A: 3 articles (06/2004 - 01/2002)
6.	Loprinzi, Charles L: 3 articles (06/2004 - 01/2002)
7.	Schuster, M W: 3 articles (01/2001 - 01/2000)
8.	Wu, S Y: 3 articles (01/2001 - 01/2000)
9.	Olson, J S: 3 articles (01/2001 - 01/2000)
10.	Stevens, M R: 3 articles (01/2001 - 01/2000)

Related Diseases

1.	Breast Neoplasms (Breast Cancer) 04/01/1988 - "These data indicate that high-dose megestrol acetate is well tolerated and effective in patients with advanced breast cancer refractory to multiple previous therapies" 10/01/1996 - "Megestrol acetate is an effective treatment for advanced breast cancer in older women when used either as first- or second-line treatment" 08/01/1991 - "To determine the tolerability and efficacy of increasing doses of megestrol acetate in the treatment of metastatic breast cancer, we conducted a phase I/II study among 57 patients" 12/01/2008 - "Goodwin et al. have performed a 6-month, double-blind, randomized, placebo-controlled trial of megestrol acetate in 286 women with breast cancer" 04/01/2008 - "Phase III randomized placebo-controlled trial of two doses of megestrol acetate as treatment for menopausal symptoms in women with breast cancer: Southwest Oncology Group Study 9626." Order ALL the reference details at left...
2.	Neoplasms (Cancer) 01/01/1993 - "Studies have demonstrated that megestrol acetate has the most positive results in patients with advanced cancer and human immunodeficiency virus" 04/01/1997 - "In this current study, we attempt to determine the effect of megestrol acetate and prepulsid on appetite and nutritional improvement in patients with head and neck cancers undergoing radiotherapy" 03/01/1997 - "Improved quality of life with megestrol acetate in patients with endocrine-insensitive advanced cancer: a randomised placebo-controlled trial" 04/01/1997 - "Effect of megestrol acetate and prepulsid on nutritional improvement in patients with head and neck cancers undergoing radiotherapy." 07/06/2002 - "MATERIAL AND METHOD: A systematic review of randomized clinical trials comparing megestrol acetate with placebo in cancer patients was performed" Order ALL the reference details at left...
3.	Anorexia 01/01/2006 - "Megestrol acetate use for anorexia in the older subject." 02/01/1994 - "Treatment of anorexia with megestrol acetate"." 06/01/1993 - "Treatment of anorexia with megestrol acetate." 08/01/1992 - "The patients were treated with megestrol acetate (160 mg tid) because they complained of anorexia" 02/01/1992 - "Severe, persistent anorexia that does not respond to dietary counseling can be reversed with megestrol acetate" Order ALL the reference details at left...
4.	Cachexia 05/01/1989 - "Nursing interventions to stimulate appetite and promote greater food intake, coupled with the use of agents that alter metabolism, such as megestrol acetate, may reverse the trend of cachexia and thus provide an increased sense of well-being and improved quality of life." 08/01/1998 - "Anticachectic efficacy of megestrol acetate at different doses and versus placebo in patients with neoplastic cachexia." 01/01/2006 - "The aim is to review major clinical trials that have used megestrol acetate (MA) in the treatment of cachexia across several disease states" 12/01/1990 - "The true effectiveness of megestrol acetate for HIV-related cachexia and the effects of treatment on quality of life are currently being assessed in a national prospective, randomized, double-blind, placebo-controlled trial." 04/01/1988 - "Studies of high-dose megestrol acetate: potential applications in cachexia." Order ALL the reference details at left...
5.	Weight Gain 04/01/2002 - "CONCLUSIONS: Short-term use of megestrol acetate results in significant weight gain and improved pulmonary function in malnourished subjects with CF" 10/01/1994 - "Megestrol acetate-treated patients had a significantly greater mean maximum weight gain (p = 0.027) and appetite stimulation (p = 0.021) than did placebo-treated patients" 09/15/1994 - "Compared with patients receiving placebo at the time of maximum weight change, evaluable patients receiving megestrol acetate, 800 mg/d, reported improvement in overall well-being and had an increase in mean weight gain (-0.725 compared with 3.54 kg [-1.6 compared with +7.8 pounds]; P < 0.001), lean body mass (-0.772 compared with +1.14 kg [-1.7 compared with +2.5 pounds]; P < 0.001), appetite grade (P < 0.001), and caloric intake (-107 compared with +645.6 calories/d; P = 0.001)" 09/01/2000 - "The purpose of this study was to determine whether the administration of megestrol acetate (MA) induces weight gain in malnourished patients with CF, and to assess the composition of weight gain" 01/01/1995 - "The second study, enrolling 271 patients, showed a dose-dependent, step-wise relationship between megestrol acetate administration and weight gain" Order ALL the reference details at left...

Related Drugs and Biologics

1.	Tamoxifen
2.	Hormones
3.	letrozole (Femara)
4.	Medroxyprogesterone 17-Acetate (Depo-Provera)
5.	Progestins (Progestagens)
6.	Aromatase Inhibitors
7.	anastrozole (Arimidex)
8.	exemestane (Aromasin)
9.	Aminoglutethimide (Cytadren)
10.	Estrogens (Estrogen)

Related Therapies and Procedures

1.	Palliative Care (Palliative Medicine)
2.	Drug Therapy (Chemotherapy)
3.	Aftercare (After-Treatment)
4.	Home Nursing (Nursing, Home)
5.	Ovariectomy (Oophorectomy)

Best Treatments:
Research Summary Report
on Breast Neoplasms

CureHunter Patient-Physician Summary Reports collect in one document all the medications ever reported in the US National Library of Medicine—1949 to the present—to be effective against your target disease. CureHunter research summary reports will vary in length from 25 to 250 pages. Analytic charts allow you and your physicians to see at a glance your medication options—including new, promising, off-label and experimental all rated for clinical efficacy.

Free Updates for 1 Year
All 3584 Outcomes
Top 200 Key Drugs and Biologics
Top 50 Key Therapies and Procedures
Detailed History Charts
Full Research Reference Details
Sample PDF Report on Psoriasis >>

Price:

$24.00 & Delivery via PDF download
updates for 1 year

Research Interface

Rapidly retrieve summaries of all the evidence for any disease in seconds. Save hours of search and analysis time. CureHunter is unlike any "search engine" you have ever used. Where standard "search engines" produce lists of links, CureHunter quantifies evidence, extracts it from the literature and calculates a result you can use to immediately facilitate evidence based decision making in Real Clinical Time.

Unlimited Disease, Drug and Therapy Search
2 clicks from Disease to Drug to Evidence
Trial References
All the Positive Outcomes
Detailed Relationship Timeline Charts
Full Article Reference Details
Includes Mobile Interface Subscription
One-click to FDA Products/Patents
Request Institution License Details >>

Price:

$490.00 access via web interface
1 year subscription

Proceed to Checkout >>

Mobile Interface

Retrieve summaries of all the evidence for any disease from your Mobile Phone or PDA. Accelerate decision making in the field. Speed up your study of new drug and disease domains. Refresh your knowledge on the road.

Access from any web enabled PDA or Phone
Trial references
All the Positive Outcomes
Drug and Therapy searches
Full Article Reference Details
Try Mobile Interface >>

Price:

$45.00 access via "curehunter.com/m"
1 year subscription

Proceed to Checkout >>