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Thapsigargin

A sesquiterpene lactone found in roots of THAPSIA. It inhibits CA(2+)-TRANSPORTING ATPASE mediated uptake of CALCIUM into SARCOPLASMIC RETICULUM.
Networked: 482 relevant articles (11 outcomes, 38 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Isaacs, John T: 7 articles (05/2015 - 07/2003)
2. Denmeade, Samuel R: 7 articles (05/2015 - 07/2003)
3. Jiang, Chen Chen: 7 articles (01/2015 - 10/2007)
4. Zhang, Xu Dong: 7 articles (01/2015 - 10/2007)
5. Hersey, Peter: 5 articles (09/2009 - 10/2007)
6. Saatcioglu, Fahri: 4 articles (01/2011 - 02/2002)
7. Denmeade, S R: 4 articles (05/2002 - 06/2000)
8. Prevarskaya, Natalia: 3 articles (11/2013 - 07/2004)
9. Pariente, José A: 3 articles (09/2009 - 08/2006)
10. Thorne, Rick F: 3 articles (08/2008 - 11/2007)

Related Diseases

1. Anoxia (Hypoxia)
2. Neuroblastoma
3. Neoplasms (Cancer)
4. Brain Ischemia (Cerebral Ischemia)
5. Ischemia

Related Drugs and Biologics

1. Tunicamycin
2. Calcium
3. Fura-2 (Fura 2)
4. Oxygen
5. Glucose (Dextrose)
6. trilobolide
7. Ryanodine
8. Staurosporine
9. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
10. Glutamic Acid (Glutamate)

Related Therapies and Procedures

1. Transplants (Transplant)
2. Ligation
3. Aftercare (After-Treatment)
4. Heterologous Transplantation (Xenotransplantation)
5. Chemoprevention