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Radiopharmaceuticals

Compounds that are used in medicine as sources of radiation for radiotherapy and for diagnostic purposes. They have numerous uses in research and industry. (Martindale, The Extra Pharmacopoeia, 30th ed, p1161)
Networked: 1019 relevant articles (54 outcomes, 108 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Saji, Hideo: 9 articles (01/2014 - 07/2003)
2. Anderson, Carolyn J: 8 articles (03/2014 - 10/2003)
3. Schibli, Roger: 8 articles (01/2014 - 10/2006)
4. Müller, Cristina: 7 articles (01/2014 - 10/2006)
5. Ferro-Flores, Guillermina: 6 articles (06/2015 - 02/2003)
6. Elsinga, Philip H: 6 articles (05/2015 - 02/2002)
7. Signore, A: 6 articles (03/2015 - 01/2003)
8. Hoffman, Timothy J: 6 articles (02/2015 - 03/2002)
9. Rubello, Domenico: 6 articles (01/2014 - 05/2008)
10. Mukai, Takahiro: 6 articles (01/2013 - 09/2004)

Related Diseases

1. Neoplasms (Cancer)
01/01/2015 - "In early clinical studies of safety and efficacy of the most common bone-seeking radiopharmaceuticals in single administration there were not any preferences in overall survival but individual clinical cases with extraordinary tumor regression after radionuclide therapy were reported. "
12/15/2000 - "The gain in avidity resulting from multivalency along with an improved biological half-life makes the tetravalent construct an important reagent for cancer therapy and diagnosis in MAb-based radiopharmaceuticals."
06/01/1993 - "Thanks to the various available radiopharmaceuticals, the ability of the tracers to document specific functional aspects, the improved methods for visualization and quantitation of organ injury and the possibilities of physiological or pharmacological intervention, nuclear medicine gives the clinician potent tools for the monitoring of organ function at risk during cancer therapy. "
05/01/2000 - "Radiolabeled anti-EGFR MAbs would be more effective for tumor imaging in cancer patients than peptide-based radiopharmaceuticals such as hEGF, because they exhibit higher tumor uptake at only moderately lower tumor-to-blood ratios."
01/01/2007 - "Given the poor therapeutic benefit obtained with cytotoxic therapeutic agents and empirical radiopharmaceuticals, so far used only for neoadjuvant and adjuvant treatments of cancer, we have tried to develop Paul Ehrlich's 'chemotherapia specifica' for safe and effective therapy of cancers in cigarette smokers. "
2. Pain (Aches)
3. Neoplasm Metastasis (Metastasis)
4. Prostatic Neoplasms (Prostate Cancer)
5. Breast Neoplasms (Breast Cancer)

Related Drugs and Biologics

1. Biological Markers (Surrogate Marker)
2. Octreotide (Sandostatin)
3. Somatostatin Receptors (Somatostatin Receptor)
4. Somatostatin (Somatotropin Release-Inhibiting Factor)
5. Estrogens (Estrogen)
6. Pentetic Acid (DTPA)
7. Strontium
8. Amino Acids
9. EDDA (NiEDDA)
10. alpha-glucoheptonic acid (calcium glucoheptonate)

Related Therapies and Procedures

1. Gamma Cameras (Gamma Camera)
2. Radiotherapy
3. Drug Therapy (Chemotherapy)
4. Castration
5. Stem Cell Transplantation