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Leukocyte Elastase (Neutrophil Elastase)

An enzyme that catalyzes the hydrolysis of proteins, including elastin. It cleaves preferentially bonds at the carboxyl side of Ala and Val, with greater specificity for Ala. EC 3.4.21.37.
Also Known As:
Neutrophil Elastase; Elastase, Neutrophil; Granulocyte Elastase; Elastase, Granulocyte; Elastase, Leukocyte; Elastase, Lysosomal; Elastase, PMN; Elastase, Polymorphonuclear Leukocyte; Leukocyte Elastase, Polymorphonuclear; Lysosomal Elastase; PMN Elastase; Polymorphonuclear Leukocyte Elastase
Networked: 2190 relevant articles (61 outcomes, 222 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Voynow, Judith A: 17 articles (01/2022 - 04/2003)
2. McElvaney, Noel G: 15 articles (07/2020 - 06/2003)
3. Stick, Stephen M: 12 articles (01/2022 - 07/2009)
4. Dale, David C: 12 articles (01/2020 - 04/2002)
5. Sly, Peter D: 11 articles (01/2022 - 07/2009)
6. Chalmers, James D: 11 articles (01/2021 - 01/2014)
7. Welte, Karl: 11 articles (01/2020 - 07/2006)
8. Gando, Satoshi: 11 articles (07/2013 - 08/2002)
9. Stockley, Robert A: 10 articles (01/2022 - 05/2006)
10. Zheng, Shuo: 10 articles (01/2022 - 09/2007)

Related Diseases

1. Emphysema
2. Acute Lung Injury
3. Inflammation (Inflammations)
4. Periodontitis
5. Lung Diseases (Lung Disease)

Related Drugs and Biologics

1. sivelestat
2. Sodium
3. Protease Inhibitors (Protease Inhibitor)
4. Peptides (Polypeptides)
5. Enzymes
6. Peptide Hydrolases (Proteases)
7. Peroxidase (Myeloperoxidase)
8. Pancreatic Elastase (Elastase)
9. Interleukin-8 (Interleukin 8)
10. Cytokines

Related Therapies and Procedures

1. Therapeutics
2. Esophagectomy
3. Root Planing
4. Heart Transplantation (Grafting, Heart)
5. Renal Dialysis (Hemodialysis)