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Phosphatidylinositol 4,5-Diphosphate (Phosphatidylinositol 4,5 Diphosphate)

A phosphoinositide present in all eukaryotic cells, particularly in the plasma membrane. It is the major substrate for receptor-stimulated phosphoinositidase C, with the consequent formation of inositol 1,4,5-triphosphate and diacylglycerol, and probably also for receptor-stimulated inositol phospholipid 3-kinase. (Kendrew, The Encyclopedia of Molecular Biology, 1994)
Also Known As:
Phosphatidylinositol 4,5 Diphosphate; Phosphatidylinositol 4,5-Biphosphate; Phosphatidylinositol Phosphate, PtdIns(4,5)P2; Phosphatidylinositol-4,5-Biphosphate; PtIns 4,5-P2; PtdIns(4,5)P2; PtdInsP; 4,5-Biphosphate, Phosphatidylinositol; 4,5-Diphosphate, Phosphatidylinositol; Phosphatidylinositol 4,5 Biphosphate; PtdInsP2
Networked: 26 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Payrastre, Bernard: 2 articles (01/2014 - 07/2003)
2. Divecha, Nullin: 2 articles (12/2005 - 07/2003)
3. Radhakrishnan, Ravi: 1 article (05/2015)
4. Wang, Yu-Hsiu: 1 article (05/2015)
5. Slochower, David R: 1 article (05/2015)
6. Janmey, Paul A: 1 article (05/2015)
7. Liao, Yihan: 1 article (02/2015)
8. Sun, Yue: 1 article (02/2015)
9. Tan, Xiaojun: 1 article (02/2015)
10. Hedman, Andrew C: 1 article (02/2015)

Related Diseases

1. Neuroblastoma
2. Neurodegenerative Diseases (Neurodegenerative Disease)
3. Neoplasms (Cancer)
4. Oculocerebrorenal Syndrome (Lowe Syndrome)
5. Cysts

Related Drugs and Biologics

1. Phosphatidylinositols (Phosphatidylinositol)
2. phosphatidylinositol 3,4,5-triphosphate
3. Insulin (Novolin)
4. Inositol (Myoinositol)
5. Phosphatidylinositol 4,5-Diphosphate (Phosphatidylinositol 4,5 Diphosphate)
6. Type C Phospholipases
7. PTEN Phosphohydrolase (PTEN Phosphatase)
8. Dynamins (Dynamin)
9. CD3 Antigens (CD3 Complex)
10. Staphylococcal Protein A (A, Protein)