Quinpirole

01/01/2019 - "However, other unconditioned behavioral effects of quinpirole (yawning and hypothermia) remained unchanged. "
10/01/2017 - "Quinpirole also produced dose-dependent hypothermia, which was not affected by either TAAR1 agonist. "
08/01/2014 - "Quinpirole (0.0032-0.32 mg/kg) produced hypothermia and a low frequency of yawning. "
01/01/2010 - "The same antagonists were studied for their ability to attenuate quinpirole-induced yawning and hypothermia. "
09/01/1991 - "Quinpirole (0.125 to 1.0 mg/kg) was equiefficacious and equipotent in producing hypothermia in all 4 strains. "

05/01/1995 - "In young adult monkeys, low quinpirole doses impaired performance of the PFC and fine motor tasks, while higher doses improved memory performance and induced dyskinesias and "hallucinatory-like" behaviors. "
11/01/2023 - "Contrary to our hypothesis, quinpirole monotherapy was the most effective at reducing dyskinesia severity and preventing abnormal mushroom spine formation on MSNs, a structural phenomenon previously associated with LID. "
09/01/2007 - "The D2 family agonist quinpirole, which induced mild dyskinesia on chronic treatment, did not produce BOLD changes in the striatum or motor cortex. "
10/01/2023 - "Here we show that optogenetically-induced dyskinesia is increased by the D2-type dopamine receptor agonist quinpirole. "
12/01/1995 - "Concomitant treatment with SKF 81297 and quinpirole caused an extreme hyperarousal syndrome but antagonized acute oral dyskinesia and grooming, suggesting a synergistic effect of high-efficacy DA D1 and D2/D3 receptor agonists regarding the induction of the hyperarousal syndrome and the antagonism of acute oral dyskinesia and grooming. "

10/01/2011 - "Restricting access to standard or high-fat chow (maintaining or decreasing body weight) decreased or eliminated quinpirole-induced yawning; within 1 week of resuming free feeding, sensitivity to quinpirole was restored, although the descending limb of the dose-response curve was shifted leftward in rats eating high-fat chow. "
01/01/2023 - "Low doses of quinpirole (0.02 mg/kg body weight) induced hypolocomotion of CHL1+/+ and CHL1-/- males and females, but led to a delayed response in CHL1-/- mice. "
11/01/2021 - "Prior to the choice test, rats were given intra-peritoneal quinpirole (0.01-0.1 mg/kg) body weight. "
01/01/2020 - "C57BL/6 ("B6") mice, raised either in a visually normal or unilateral form-deprivation environment, were divided into three subgroups, including an intraperitoneally injected (IP) vehicle group and two quinpirole (1 and 10 µg/g body weight) treatment groups. "
01/01/2019 - "Body weight, food consumption, and sensitivity to quinpirole-induced (0.0032-0.32 mg/kg) penile erections were examined throughout the course of the experiment. "

08/01/2023 - "Quinpirole ameliorates nigral dopaminergic neuron damage in Parkinson's disease mouse model through activating GHS-R1a/D2R heterodimers."
02/01/1995 - "The differential behavioural effects of benzazepine D1 dopamine agonists with varying efficacies, co-administered with quinpirole in primate and rodent models of Parkinson's disease."
08/01/1987 - "Quinpirole hydrochloride, a putative dopamine agonist, was investigated in animal models of central dopaminergic activity, to evaluate its possible role in the treatment of Parkinson's disease. "
08/01/1987 - "Quinpirole differs from other dopaminergic drugs and may be useful for the therapy of Parkinson's disease."
07/01/2014 - "They also displayed reduced abnormal involuntary movements after apomorphine and quinpirole treatment in the mouse dyskinesia model of Parkinson's disease. "

03/01/1995 - "Quinpirole was found to be more effective in attenuating amnesia than forgetfulness."
05/01/2001 - "Under the amnesia conditions, quinpirole reactivated the passive avoidance retrieval irrespective of the base initial behavior status (aggressive versus submissive). "
05/01/2001 - "The effect of quinpirole on the passive avoidance habit retention in male C57BL/6J mice with aggressive and submissive behavioral strategies was studied during the habit extinction and amnesia. "
05/01/2001 - "[Compensating and reactivating effects of quinpirole on extinction of conditioned response and amnesia in mice with alternative behavioral stereotypes]."
03/01/1989 - "[Effect of quinpirole on the retrieval of a memory trace in amnesia]."