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NADPH Oxidase (NAD(P)H oxidase)

A flavoprotein enzyme that catalyzes the univalent reduction of OXYGEN using NADPH as an electron donor to create SUPEROXIDE ANION. The enzyme is dependent on a variety of CYTOCHROMES. Defects in the production of superoxide ions by enzymes such as NADPH oxidase result in GRANULOMATOUS DISEASE, CHRONIC.
Also Known As:
NAD(P)H oxidase; Oxidase, NADPH
Networked: 2686 relevant articles (71 outcomes, 311 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Dusting, Gregory J: 24 articles (01/2015 - 07/2002)
2. Shah, Ajay M: 22 articles (07/2015 - 01/2002)
3. Holland, Steven M: 22 articles (02/2015 - 03/2002)
4. Zalba, Guillermo: 21 articles (09/2015 - 08/2004)
5. Segal, Brahm H: 21 articles (05/2014 - 03/2002)
6. Holmdahl, Rikard: 20 articles (01/2016 - 01/2003)
7. Roos, Dirk: 20 articles (12/2015 - 03/2003)
8. Drummond, Grant R: 20 articles (01/2015 - 07/2002)
9. Fortuño, Ana: 18 articles (09/2015 - 08/2004)
10. Touyz, Rhian M: 18 articles (04/2015 - 12/2002)

Related Diseases

1. Inflammation
2. Fibrosis (Cirrhosis)
3. Insulin Resistance
4. Cardiomegaly (Heart Hypertrophy)
5. Hypertension (High Blood Pressure)

Related Drugs and Biologics

1. acetovanillone (apocynin)
2. Superoxides (Superoxide)
3. Reactive Oxygen Species (Oxygen Radicals)
4. 3-nitrotyrosine
5. 4- ethoxymethylene- 2- phenyl- 2- oxazoline- 5- one (phOx)
6. Nitric Oxide Synthase (NO Synthase)
7. Antioxidants
8. Insulin (Novolin)
9. nebivolol
10. Nitric Oxide (Nitrogen Monoxide)

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1. Ligation
2. Resuscitation
3. Endarterectomy (Thromboendarterectomy)
4. Electrodes (Electrode)
5. Aftercare (After-Treatment)