Satellite RNA (Satellite RNAs)

Small, linear single-stranded RNA molecules functionally acting as molecular parasites of certain RNA plant viruses. Satellite RNAs exhibit four characteristic traits: (1) they require helper viruses to replicate; (2) they are unnecessary for the replication of helper viruses; (3) they are encapsidated in the coat protein of the helper virus; (4) they have no extensive sequence homology to the helper virus. Thus they differ from SATELLITE VIRUSES which encode their own coat protein, and from the genomic RNA; (=RNA, VIRAL); of satellite viruses. (From Maramorosch, Viroids and Satellites, 1991, p143)

Also Known As:

Networked: 93 relevant articles (2 outcomes, 7 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Obrępalska-Stęplowska, Aleksandra: 4 articles (07/2021 - 07/2013)
2.	Wrzesińska, Barbara: 3 articles (07/2021 - 01/2018)
3.	Kishikawa, Takahiro: 3 articles (01/2018 - 01/2016)
4.	Koike, Kazuhiko: 3 articles (01/2018 - 01/2016)
5.	Ohno, Motoko: 3 articles (01/2018 - 01/2016)
6.	Otsuka, Motoyuki: 3 articles (01/2018 - 01/2016)
7.	Palukaitis, Peter: 3 articles (03/2016 - 01/2002)
8.	Roossinck, Marilyn J: 3 articles (08/2012 - 06/2003)
9.	Xu, Ping: 3 articles (08/2012 - 06/2003)
10.	De Smet, Ive: 2 articles (07/2021 - 10/2018)

Related Diseases

1.	Infections 04/01/1998 - "Field trials of transgenic tomato plants expressing an ameliorative satellite RNA of cucumber mosaic virus (CMV) were conducted to test the efficacy of satellite-transgenic technology to protect against CMV infection. " 10/18/2018 - "In this study, we aimed to identify the processes affected by infection with Peanut stunt virus (PSV) and its satellite RNA (satRNA) in Nicotiana benthamiana at the early stage of pathogenesis. " 06/23/2022 - "Although mechanically transmitted to experimental cucumber plants, the role of satellite RNA in the symptomatology observed could not be established due to a complex infection of original hosts with different viruses." 01/01/2022 - "Multiplex reverse transcription-polymerase chain reaction (mRT-PCR) was developed for validation of sRNA-seq predicted infections, including various combinations of viruses or viroids and satellite RNA. " 01/01/2021 - "The response of Col-0 to a series of reassortant CMVs between CMV(Ho)tr and CMV(Y) suggested that the establishment of an asymptomatic phenotype of CMV(Ho) infection was due to the 2b gene of CMV RNA2, but not due to the presence of the defective RNA3 and satellite RNA. "
2.	Coinfection 01/01/2016 - "Improved Pathogenicity of a Beet Black Scorch Virus Variant by Low Temperature and Co-infection with Its Satellite RNA." 05/01/2016 - "Twelve cultivars of groundnut were screened in field trials for resistance to groundnut rosette disease (GRD), caused by coinfection with Groundnut rosette assistor virus (GRAV), Groundnut rosette virus (GRV), and its satellite RNA in the coastal savannah of Ghana. " 09/01/2022 - "While CPPV1-Pv was consistently detected in mixed infection with ETBTV and its satellite RNA molecule, based on results of mechanical transmission assays it does not appear to be involved in disease etiology, suggesting that its role may be limited to being a helper virus for the umbravirus. " 01/01/2016 - "Co-infection of none-coding satellite RNAs (sat-RNAs) usually inhibits replication and attenuates disease symptoms of helper viruses. " 01/01/1993 - "Satellite RNA depend for their multiplication on the co-infection of a host cell by a helper virus which can itself multiply independently of the satellite. "
3.	Necrosis 09/15/1997 - "Data from previous mutational and sequence comparison studies between satellite RNA strains inducing necrosis in tomato plants and those strains not inducing necrosis allowed us to identify one helix and two tetraloop regions correlating with the necrogenicity syndrome." 01/01/2016 - "The satellite RNAs of cucumber mosaic virus (CMV) that induce systemic necrosis in tomato plants (N-satRNA) multiply to high levels in the infected host while severely depressing CMV accumulation and, hence, its aphid transmission efficiency. " 08/01/2012 - "Cucumber mosaic virus (CMV) associated with D satellite RNA (satRNA) causes lethal systemic necrosis (LSN) in tomato (Solanum lycopersicum), which involves programmed cell death. " 06/01/2003 - "Cucumber mosaic virus (CMV) D satellite RNA (satRNA) attenuates the symptoms induced by CMV in most plants, but causes leaf epinasty and systemic necrosis in tomato plants, where programmed cell death (PCD) is involved. " 06/01/2003 - "In spite of induced multiple defense responses, tomato plants infected with Cucumber mosaic virus and D satellite RNA succumb to systemic necrosis."
4.	Neoplasms (Cancer) 01/01/2018 - "These studies lay the foundation for developing novel therapeutic strategies that block the effects of non-coding satellite RNAs in cancer cells." 04/01/2022 - "One interesting group of noncoding RNAs strongly linked to cancers are heterochromatic repetitive Satellite RNAs. " 01/01/2018 - "Here we provide evidence that increased levels of satellite RNAs in mammary glands induce tumor formation in mice. " 01/01/2018 - "Heterochromatic repetitive satellite RNAs are extensively transcribed in a variety of human cancers, including BRCA1 mutant breast cancer. " 01/01/2018 - "Satellite RNA Increases DNA Damage and Accelerates Tumor Formation in Mouse Models of Pancreatic Cancer."
5.	Virus Diseases (Viral Diseases) 05/01/2011 - "Our findings provide direct evidence that the identified siRNAs derived from viral satellite RNA directly modulate the viral disease symptom by RNA silencing-based regulation of a host gene." 07/01/2001 - "This is the first report of any satellite RNA associated with a virus infection in Lobelia and the first report of CMV in this host in Ohio. " 09/01/2000 - "ABSTRACT St. Augustine decline is a viral disease caused by Panicum mosaic virus (PMV) alone or in combination with a satellite virus (SPMV) and/or satellite RNAs (satRNAs). " 10/01/1996 - "However, in this system, some satellite RNAs also intensify viral disease in particular host plants. " 09/01/1995 - "Pseudorecombinant virus infections between CMV-1 and CMV-Ix indicated that the genomic determinants responsible for this phenotype reside on RNA 1 since only combinations with CMV-Ix RNA 1 failed to replicate satellite RNA. "

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	Proteome
3.	Phosphoproteins
4.	RNA (Ribonucleic Acid)
5.	Nucleotides
6.	Satellite RNA (Satellite RNAs)
7.	Heterochromatin
8.	Complementary DNA (cDNA)
9.	Biomarkers (Surrogate Marker)
10.	Hepatitis B Surface Antigens (HBsAg)

Related Therapies and Procedures

1.	Castration