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Troponin I

A TROPONIN complex subunit that inhibits ACTOMYOSIN ATPASE activity thereby disrupting ACTIN and MYOSIN interaction. There are three troponin I subtypes: troponin I1, I2 and I3. Troponin I3 is cardiac-specific whereas troponin I1 and I2 are skeletal subtypes. Troponin I3 is a BIOMARKER for damaged or injured CARDIAC MYOCYTES and mutations in troponin I3 gene are associated with FAMILIAL HYPERTROPHIC CARDIOMYOPATHY.
Also Known As:
Troponin I1; Troponin I2; Troponin I3; Troponin-I
Networked: 4805 relevant articles (143 outcomes, 580 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Apple, Fred S: 44 articles (07/2022 - 06/2002)
2. Blankenberg, Stefan: 43 articles (01/2020 - 08/2009)
3. Zeller, Tanja: 40 articles (01/2021 - 08/2009)
4. Lindahl, Bertil: 39 articles (02/2022 - 06/2003)
5. Mills, Nicholas L: 39 articles (01/2022 - 03/2011)
6. Mueller, Christian: 39 articles (12/2021 - 05/2008)
7. Twerenbold, Raphael: 32 articles (12/2021 - 10/2013)
8. Newby, David E: 28 articles (01/2022 - 04/2010)
9. Jaffe, Allan S: 28 articles (01/2019 - 01/2002)
10. Shah, Anoop S V: 27 articles (01/2022 - 03/2011)

Related Diseases

1. Myocardial Infarction
2. Infarction (Infarctions)
3. Acute Coronary Syndrome
4. Chest Pain (Chest Pains)
5. Cardiovascular Diseases (Cardiovascular Disease)

Related Drugs and Biologics

1. Biomarkers (Surrogate Marker)
2. Creatine Kinase (Creatine Phosphokinase)
3. Troponin T (Troponin T1)
4. MB Form Creatine Kinase
5. Proteins (Proteins, Gene)
6. L-Lactate Dehydrogenase (Lactate Dehydrogenase)
7. Brain Natriuretic Peptide (Natrecor)
8. pro-brain natriuretic peptide (1-76)
9. Enzymes
10. C-Reactive Protein

Related Therapies and Procedures

1. Therapeutics
2. Coronary Artery Bypass (Coronary Artery Bypass Surgery)
3. Aftercare (After-Treatment)
4. Artificial Respiration (Mechanical Ventilation)
5. Intraperitoneal Injections