|1.||Maggiolini, Marcello: 23 articles (10/2015 - 06/2004)|
|2.||Prossnitz, Eric R: 18 articles (05/2015 - 02/2007)|
|3.||Gutkind, J Silvio: 16 articles (11/2014 - 04/2004)|
|4.||Koch, Walter J: 15 articles (12/2015 - 11/2003)|
|5.||Siffert, Winfried: 15 articles (12/2014 - 02/2003)|
|6.||Wang, Ji Ming: 15 articles (11/2012 - 02/2004)|
|7.||Tripp, Ralph A: 14 articles (09/2015 - 12/2004)|
|8.||Okajima, Fumikazu: 14 articles (02/2015 - 10/2004)|
|9.||Vivacqua, Adele: 13 articles (06/2015 - 06/2004)|
|10.||Offermanns, Stefan: 12 articles (01/2016 - 10/2003)|
12/01/1997 - "These results indicate that the G protein of BRSV can induce significant protection against BRSV infection in cattle, and that the BHV1/BRSV-G vaccine protects effectively against a subsequent BRSV and BHV1 infection."
11/03/2011 - "These results suggest that the LaSota recombinant virus is a safe and effective vaccine vector and that expression of the aMPV-C G protein alone is not sufficient to provide full protection against an aMPV-C infection. "
10/01/2013 - "The objectives of this study were: 1) to determine the transcriptional profiles of G-protein coupled receptor 18 (GPR18) in channel catfish after infection with Aeromonas hydrophila compared to that in healthy catfish; 2) to determine whether over-expression of GPR18 in catfish gill cells will offer protection against infection of A. hydrophila; 3) to determine whether recombinant pcDNA-GPR18 could be used as an immunostimulant to protect channel catfish against A. hydrophila infection. "
09/01/2010 - "This study shows that an anti-RSV G protein MAb might provide prophylaxis against both primary infection and FI-RSV-associated enhanced disease. "
02/01/2006 - "In this study, we show that expression of the RSV G protein or the G protein CX3C motif during infection is associated with reduced CX3CR1+ T cell trafficking to the lung, reduced frequencies of RSV-specific, MHC class I-restricted IFN-gamma-expressing cells, and lower numbers of IL-4- and CX3CL1-expressing cells. "
|2.||Body Weight (Weight, Body)
04/01/1989 - "It was particularly significantly greater than that of the LP rats between week 3 and 5 where an important decrease was observed in this group (1.99 +/- 0.36 vs. 3.23 +/- 0.58 g body weight/g protein during the 1-3 weeks period). "
02/01/2014 - "Exercise trials differed only in the postexercise nutritional intervention: EX-FED (5 kcal, 0.83 g carbohydrate, 0.37 g protein, 0.03 g fat per kg body weight) and EX-FAST (noncaloric, isovolumic placebo) ingested immediately and one hour after exercise. "
08/01/2013 - "To help older people (>65 years) maintain and regain lean body mass and function, the PROT-AGE study group recommends average daily intake at least in the range of 1.0 to 1.2 g protein per kilogram of body weight per day. "
04/01/2009 - "In this study, 11 normal subjects consumed controlled oxalate diets containing 0.6, 1.2 and 1.8 g protein/kg body weight/day. "
01/01/1998 - "In a randomized crossover trial, the patients were given each diet (each containing 0.75 g protein and 32 kcal per kilogram body weight) for a 6-month period. "
09/01/1992 - "Direct sequencing of PCR reaction products identified the mutations as R201-H, R201-S and R201-C in exon 8 and Q227-L in exon 9. These results show the efficacy of PCR/SSCP analysis in the detection of G protein mutations and extend the generalization that these sites are hot spots in tumor-inducing mutations."
01/01/2015 - "Recent studies have shown that repression of regulator of G-protein signaling (RGS) 2 increases cancer cell growth. "
10/30/2014 - "In this study, we demonstrated that expression of the heterotrimeric G-protein alpha-12 (Gα12) is highly up-regulated in primary tumors and LN of OSCC patients, as assessed by quantitative polymerase chain reaction (qPCR) and immunohistochemistry (IHC). "
06/01/2013 - "These studies indicate that G proteins, GPCRs and their linked signalling circuitry represent novel therapeutic targets for cancer prevention and treatment."
03/01/2013 - "Future studies will now focus on defining how this G-protein-coupled receptor is coupled to the activation of p53, a tumor suppressor gene that is mutated in more than 50% of all human cancers."
|4.||Hypertension (High Blood Pressure)
01/01/2016 - "This study aims to understand the role of procontractile G-protein-mediated signalling pathways in vascular smooth muscle in age-dependent hypertension. "
01/01/2013 - "The G-protein β3-subunit gene C825T polymorphism (GNB3-C825T) has been reported to be associated with essential hypertension (EH), but results from previous studies are conflicting. "
01/01/2011 - "In this study, we have investigated the potential role of the C825T, C1429T, and G5177A polymorphisms of the β3 subunit of G-proteins in essential hypertension in a group of Turkish subjects. "
01/01/2011 - "Several studies have demonstrated an association between G protein polymorphisms and essential hypertension in some populations, although contradictive results also exist. "
10/01/2010 - "Several studies examining the C825T polymorphism of the G protein β3 subunit (GNB3) have shown inconsistent results regarding susceptibility to hypertension. "
|5.||Alzheimer Disease (Alzheimer's Disease)
11/01/1995 - "Previous studies examining the functional status of cortical muscarinic cholinergic M1 receptors have demonstrated an impairment in receptor-G protein coupling in Alzheimer's disease (AD) as measured by the inability of the receptor to form a high affinity agonist binding site. "
07/01/1991 - "The aim of this study was to establish whether the level of G alpha subunits of five G proteins was altered in Alzheimer's disease. "
07/01/1991 - "Robustness of G proteins in Alzheimer's disease: an immunoblot study."
07/01/2009 - "In this review, we discuss the role of this recently discovered G protein-coupled receptor in cognition and memory, particularly in Alzheimer's disease. "
05/01/2009 - "These results also suggest that specific antagonists of G-protein activity may have a therapeutic relevance in Alzheimer's disease."
|1.||GTP-Binding Proteins (G-Protein)
|5.||DNA (Deoxyribonucleic Acid)
|6.||Messenger RNA (mRNA)
|8.||Muscarinic Receptors (Muscarinic Acetylcholine Receptor)
|1.||Phototherapy (Light Therapy)
|2.||Protein-Restricted Diet (Diet, Protein Restricted)
|4.||Investigational Therapies (Experimental Therapy)