Artificial Liver (Bioartificial Liver)

01/01/2005 - "Animal models of fulminant hepatic failure (FHF) are important for studying the pathophysiology of this process and for evaluation of the efficacy of artificial and bioartificial liver support systems. "
06/06/1998 - "Despite good results of orthotopic liver transplantation in patients with fulminant hepatic failure the need still exists for an effective and safe artificial liver, able to temporarily take over the complex liver function so as to bridge the gap with transplantation or regeneration. "
01/01/2022 - "There is no effective treatment for acute liver failure (ALF) except for an artificial liver support system (ALSS) and liver transplant. "
11/01/2011 - "The application of newly developed multi-layer flat-plate bioartificial liver system was effective in the treatment of canines with acute liver failure."
05/21/2010 - "On-line hemodiafiltration was effective in patients with acute liver failure, and consciousness was maintained for the duration of artificial liver support, even in those in whom it was considered that hepatic function was completely abolished."

01/01/2018 - "After artificial liver treatment, the liver function and coagulation function of liver failure patients were significantly improved (P < 0.01), the Meld score was lower than that before treatment, and the difference was statistically significant (P < 0.05). "
01/01/2006 - "The significant improvement of survival times and pathological parameters by bioartificial liver with recombinant HepG2 in porcine liver failure model."
06/01/2014 - "Non-bioartificial liver support systems (NBALs) have been shown to be effective in improving the clinical symptoms and laboratory parameters of patients with liver failure. "
03/14/2007 - "Bioartificial liver support, in which living liver tissue is used to support hepatic function, has been anticipated as an effective treatment for hepatic failure. "
01/01/2002 - "Bioartificial liver support systems containing adsorbent devices, xenogeneic whole liver perfusion, and hybrid bioartificial liver are anticipated to be effective for the treatment of severe hepatic failure. "

01/01/2004 - "Middle artificial liver is effective in the treatment of severe hepatitis."
06/01/2002 - "To investigate the method and therapeutic efficacy of artificial liver support system (ALSS) in treatment of severe viral hepatitis. "
09/01/2003 - "The survival of patients excluded from liver transplantation or those with potentially reversible acute hepatitis might be improved with temporary artificial liver support. "
08/01/2003 - "To evaluate the efficacy of a hybrid artificial liver support system in the treatment of chronic severe hepatitis. "
10/28/2001 - "To evaluate the efficacy of mid-artificial liver support system (ALSS) on viral hepatitis gravis. "

04/28/2023 - "Nonbiological artificial liver (NBAL) is frequently used as a first-line treatment for hepatitis B virus-associated acute-on-chronic liver failure (HBV-ACLF). "
01/01/2023 - "To evaluate the short-term and long-term survival efficacy of an artificial liver support system (ALSS) in patients with acute-on-chronic liver failure (ACLF). "
08/01/2019 - "The artificial liver support system (ALSS) is used frequently as a first-line treatment for hepatitis B virus-associated acute-on-chronic liver failure (HBV-ACLF). "
11/25/2023 - "Characteristics of circulating immune cells in HBV-related acute-on-chronic liver failure following artificial liver treatment."
10/24/2023 - "Evaluating the Effect of Artificial Liver Support on Acute-on-Chronic Liver Failure Using the Quantitative Difference Algorithm: Retrospective Study."

09/01/1998 - "The purpose of this study was to investigate whether the efficacy of our novel extracorporeal bioartificial liver (BAL) to support rats with complete liver ischemia (LIS) could be improved by extending the culture time of freshly isolated porcine hepatocytes from 14 hours to 38 hours. "
10/01/1999 - "Significantly improved survival time in pigs with complete liver ischemia treated with a novel bioartificial liver."
02/01/1999 - "Evaluation of a novel bioartificial liver in rats with complete liver ischemia: treatment efficacy and species-specific alpha-GST detection to monitor hepatocyte viability."
10/01/2002 - "The aim of this study was to evaluate the potential interest of NMR spectroscopy in the follow-up of different plasma compounds in pigs with ischemia-induced fulminant hepatic failure treated or not with a bioartificial liver (BAL), which has been previously shown to improve the neurological status of the animals. "
11/01/2005 - "Extended liver resection and hepatic ischemia in pigs: a new, potentially reversible model to induce acute liver failure and study artificial liver support systems."