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Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)

Compounds that inhibit HMG-CoA reductases. They have been shown to directly lower cholesterol synthesis.
Also Known As:
HMG-CoA Reductase Inhibitors; Inhibitors, HMG-CoA Reductase; Inhibitors, Hydroxymethylglutaryl-CoA; Inhibitors, Hydroxymethylglutaryl-Coenzyme A; HMG CoA Reductase Inhibitors; HMG-CoA Statins; Hydroxymethylglutaryl CoA Reductase Inhibitors; Hydroxymethylglutaryl-CoA Inhibitors; Hydroxymethylglutaryl-Coenzyme A Inhibitors; Inhibitors, HMG CoA Reductase; Inhibitors, Hydroxymethylglutaryl CoA; Inhibitors, Hydroxymethylglutaryl Coenzyme A; Inhibitors, Hydroxymethylglutaryl-CoA Reductase; Reductase Inhibitors, HMG-CoA; Reductase Inhibitors, Hydroxymethylglutaryl-CoA; Statins, HMG CoA; Statins, HMG-CoA
Networked: 1027 relevant articles (90 outcomes, 172 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Laufs, Ulrich: 6 articles (03/2014 - 03/2002)
2. Liao, James K: 6 articles (05/2010 - 11/2002)
3. Böhm, Michael: 5 articles (12/2006 - 03/2002)
4. Johnson, David W: 4 articles (01/2014 - 01/2009)
5. Pfefferkorn, Jeffrey A: 4 articles (05/2011 - 01/2008)
6. Egashira, Kensuke: 4 articles (04/2010 - 11/2003)
7. Nickenig, Georg: 4 articles (12/2006 - 06/2002)
8. Lefer, David J: 4 articles (09/2006 - 04/2005)
9. Chen, Hua: 3 articles (09/2015 - 07/2011)
10. Beri, Abhimanyu: 3 articles (09/2015 - 01/2009)

Related Diseases

1. Hypercholesterolemia
2. Stroke (Strokes)
3. Coronary Disease (Coronary Heart Disease)
4. Cardiovascular Diseases (Cardiovascular Disease)
5. Dyslipidemias (Dyslipidemia)

Related Drugs and Biologics

1. Coenzyme A (CoA)
2. Cholesterol
3. Oxidoreductases
4. Fibric Acids (Fibrates)
5. Simvastatin (Zocor)
6. Lipoproteins (Lipoprotein)
7. LDL Cholesterol
8. atorvastatin (Lipitor)
9. Calcium
10. 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA)

Related Therapies and Procedures

1. Transplants (Transplant)
2. Coronary Artery Bypass (Coronary Artery Bypass Surgery)
3. Transplantation (Transplant Recipients)
4. Intensive Care (Surgical Intensive Care)
5. Drug Therapy (Chemotherapy)