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Blocking Antibodies

Antibodies that inhibit the reaction between ANTIGEN and other antibodies or sensitized T-LYMPHOCYTES (e.g., antibodies of the IMMUNOGLOBULIN G class that compete with IGE antibodies for antigen, thereby blocking an allergic response). Blocking antibodies that bind tumors and prevent destruction of tumor cells by CYTOTOXIC T-LYMPHOCYTES have also been called enhancing antibodies. (Rosen et al., Dictionary of Immunology, 1989)
Also Known As:
Antibodies, Blocking; Antibodies, Enhancing; Enhancing Antibodies
Networked: 635 relevant articles (22 outcomes, 54 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Konishi, Eiji: 5 articles (11/2015 - 12/2011)
2. Postow, Michael A: 5 articles (01/2015 - 01/2014)
3. Yamanaka, Atsushi: 4 articles (11/2015 - 11/2012)
4. Alitalo, Kari: 4 articles (08/2015 - 09/2010)
5. Wolchok, Jedd D: 4 articles (08/2015 - 01/2011)
6. Hondermarck, Hubert: 3 articles (10/2015 - 04/2011)
7. Pardoll, Drew M: 3 articles (02/2015 - 08/2013)
8. Brown, Rosalind S: 3 articles (01/2015 - 09/2004)
9. Harris, Eva: 3 articles (10/2014 - 02/2013)
10. Diamond, Michael S: 3 articles (01/2014 - 02/2013)

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2. Neoplasms (Cancer)
3. Infection
4. Renal Cell Carcinoma (Grawitz Tumor)
5. Psoriasis (Pustulosis Palmaris et Plantaris)

Related Drugs and Biologics

1. Antibodies
2. Complement System Proteins (Complement)
3. Protein Kinases (Protein Kinase)
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5. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
6. Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)
7. Protein-Tyrosine Kinases (Tyrosine Kinase)
8. Notch Receptors
9. Cell Adhesion Molecules
10. vatalanib (PTK787)

Related Therapies and Procedures

1. Immunotherapy
2. Drug Therapy (Chemotherapy)
3. Heterologous Transplantation (Xenotransplantation)
4. Therapeutics
5. Aftercare (After-Treatment)