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src-Family Kinases

A PROTEIN-TYROSINE KINASE family that was originally identified by homology to the Rous sarcoma virus ONCOGENE PROTEIN PP60(V-SRC). They interact with a variety of cell-surface receptors and participate in intracellular signal transduction pathways. Oncogenic forms of src-family kinases can occur through altered regulation or expression of the endogenous protein and by virally encoded src (v-src) genes.
Also Known As:
src Tyrosine Kinases; src-Family Tyrosine Kinases; Kinases, src; Kinases, src Protein-Tyrosine; Kinases, src Tyrosine; Tyrosine Kinases, src; Tyrosine Kinases, src-Family; src Family Kinases; src Family Tyrosine Kinases; src Protein-Tyrosine Kinases; Protein-Tyrosine Kinases, src; src Kinases
Networked: 407 relevant articles (7 outcomes, 41 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Gallick, Gary E: 9 articles (09/2014 - 12/2003)
2. Jove, Richard: 7 articles (02/2014 - 10/2005)
3. Lee, Francis Y: 7 articles (02/2010 - 10/2005)
4. Li, Shaoguang: 6 articles (01/2008 - 05/2004)
5. Lowell, Clifford A: 5 articles (09/2015 - 09/2008)
6. Johnson, Faye M: 5 articles (11/2012 - 01/2007)
7. Sakai, Ryuichi: 5 articles (11/2011 - 11/2003)
8. Cheng, Heung-Chin: 4 articles (03/2015 - 01/2011)
9. Araujo, John C: 4 articles (09/2014 - 05/2008)
10. Tanaka, Masamitsu: 4 articles (01/2013 - 07/2005)

Related Diseases

1. Neoplasms (Cancer)
2. Multiple Myeloma
3. Leukemia
4. BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
5. Philadelphia Chromosome

Related Drugs and Biologics

1. dasatinib (BMS 354825)
2. Phosphotransferases (Kinase)
3. Protein-Tyrosine Kinases (Tyrosine Kinase)
4. DNA (Deoxyribonucleic Acid)
5. epidermal growth factor receptor VIII
6. erlotinib (CP 358,774)
7. glucuronyl glucosamine glycan sulfate (Vessel)
8. Carbon Monoxide
9. Azacitidine (5 Azacytidine)
10. Tyrosine (L-Tyrosine)

Related Therapies and Procedures

1. Therapeutics
2. Heterologous Transplantation (Xenotransplantation)
3. Castration