Proto-Oncogene Proteins c-kit (Proto-Oncogene Protein c-kit)
309
relevant articles (3 outcomes,
30 trials/studies)
found for this Bio-Agent
Description:
A protein-tyrosine kinase receptor that is specific for STEM CELL FACTOR. This interaction is crucial for the development of hematopoietic, gonadal, and pigment stem cells. Genetic mutations that disrupt the expression of PROTO-ONCOGENE PROTEINS C-KIT are associated with PIEBALDISM, while overexpression or constitutive activation of the c-kit protein-tyrosine kinase is associated with tumorigenesis.
Also Known As:
Proto-Oncogene Protein c-kit; CD117 Antigen; Proto-Oncogene Protein kit; SCF Receptor; p145 c-kit; p145c-kit; Proto Oncogene Protein c kit; Proto Oncogene Protein kit; Proto Oncogene Proteins c kit; Proto-Oncogene Protein, kit; c kit Protein; c kit Receptor; c-kit, Proto-Oncogene Protein; c-kit, Proto-Oncogene Proteins; c-kit, p145; kit Proto Oncogene Protein; p145 c kit; p145c kit; Antigens, CD117; CD117 Antigens; Receptor, Stem Cell Factor; Stem Cell Factor Receptor; c-kit Protein; c-kit Receptor; kit Proto-Oncogene Protein; p145(c-kit)
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Bio-Agent Context: Research Results