|1.||Gerardy-Schahn, Rita: 14 articles (01/2015 - 08/2003)|
|2.||Schachner, Melitta: 12 articles (01/2014 - 10/2002)|
|3.||Mühlenhoff, Martina: 9 articles (10/2013 - 08/2004)|
|4.||Berezin, Vladimir: 9 articles (12/2012 - 01/2002)|
|5.||Maness, Patricia F: 8 articles (01/2014 - 05/2003)|
|6.||Kaur, Gurcharan: 8 articles (01/2014 - 05/2003)|
|7.||Bock, Elisabeth: 8 articles (12/2012 - 01/2002)|
|8.||Hildebrandt, Herbert: 7 articles (01/2015 - 08/2003)|
|9.||Horstkorte, Rüdiger: 7 articles (08/2012 - 03/2004)|
|10.||Terada, Tadashi: 6 articles (10/2014 - 01/2012)|
10/01/1998 - "This study was undertaken to evaluate polysialylated NCAM as a marker helpful in distinguishing between various embryonal tumors and other lesions suspicious of a malignancy. "
01/01/2011 - "In this tissue microarray-based immunohistochemical study, we confirmed the expression of NCAM in Wilms tumors, nephrogenic rests, and metanephric mesenchyme and its early derivatives in fetal renal cortex. "
11/01/2005 - "In the present study, we have aimed to clarify the hypothesis that NCAM-mediated inhibition of salivary gland tumor proliferation is caused by homophilic binding and involves the prevention of signal transduction for perineural invasion using HSG cells. "
05/01/2003 - "Furthermore, in such very few previous studies on NCAM expression in MCC, all the tumor cells were not necessarily demonstrated to express NCAM. "
05/15/1998 - "To the authors' knowledge, this study provides the first direct evidence that NCAM is down-regulated in the development of the malignancy of astrocytic tumors; and it is suggested that reduced NCAM expression might be involved in the development of biologic malignancy."
|2.||Neoplasm Metastasis (Metastasis)
10/01/2013 - "Importantly, significant changes were demonstrated in the protein expression level of three metastatic-associated genes (NCAM, FOXG1, and ITGA4), and knockdown of one of the identified HOPX-regulated metastatic genes, ITGA4, showed marked inhibition of cell motility and metastasis formation. "
10/01/2012 - "Treatment with low-dose ZOL can reduce NCAM expression that may contribute toward reduced spinal cord metastasis, suggesting that NCAM is an alternative therapeutic target and that the low-dose ZOL treatment protocol is a reasonable approach for its treatment."
10/01/2012 - "Low-dose ZOL significantly reduced spinal cord metastasis probably through reduced NCAM expression in vivo. "
10/01/2011 - "Soluble NCAM status was a significant independent factor predictive of long-term survival in patients with HCC, and high levels of soluble NCAM were significantly related to intrahepatic metastasis. "
04/01/2010 - "This cells line, pretreated with an anti-NCAM antibody and inoculated intravenously (i.v.) into syngeneic mice, developed less and smaller lung metastases. "
|3.||Schizophrenia (Dementia Praecox)
07/30/2010 - "In schizophrenia, a significant reduction in the ratio of the two major membrane-bound forms of NCAM (180 and 140) was observed in BA10. "
01/01/1997 - "To investigate the possible involvement of the NCAM gene in schizophrenia, we conducted a comprehensive genetic study, which included linkage analysis and an association study employing the Haplotype Relative Risk (HRR) design in nuclear families. "
01/01/1997 - "NCAM and schizophrenia: genetic studies."
01/01/2015 - "Post-mortem and genetic evidence suggests that dysregulation of polySia-NCAM is involved in schizophrenia (SZ). "
01/01/2015 - "A growing body of evidence links aberrant levels of NCAM and polySia as well as variation in the ST8SIA2 gene to neuropsychiatric disorders, including schizophrenia. "
|4.||Brain Injuries (Brain Injury)
05/30/2008 - "The synthetic NCAM-derived peptide, FGL, modulates the transcriptional response to traumatic brain injury."
06/01/2008 - "The NCAM-derived P2 peptide facilitates recovery of cognitive and motor function and ameliorates neuropathology following traumatic brain injury."
07/01/2012 - "To study the effects of astragalan (AG) on the expression of the neural cell adhesion molecule(NCAM) and c-fos of hippocampus CA1 region after the ischemic brain injury in rats. "
04/01/1997 - "Previously, we have evaluated changes in the rate of synaptic remodeling in brain injury by calculating the ratio of the neural cell adhesion molecule (NCAM) to D3(SNAP-25). "
08/28/2000 - "The regional expression of proteins associated with axonal elongation, such as microtubule-associated protein 1B (MAP1B), its phosphorylated isoform (MAP1B-P), growth-associated protein 43 (GAP-43), and polysialylated neural cell-adhesion molecule (PSA-NCAM), was examined using immunohistochemistry from 24 hours to 2 months following lateral fluid percussion brain injury of moderate severity (2.4-2.6 atmospheres) in anesthetized rats. "
|5.||Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/01/2001 - "In this study we confirm the observation of some authors that NCAM expression occurs in some cases of non-small-cell lung carcinomas."
11/01/1998 - "Neural cell adhesion molecule expression: prognosis in 889 patients with resected non-small cell lung cancer."
06/01/1996 - "We investigated the clinical significance of expression of this NCAM isoform as a prognostic factor in a series of 96 non-small cell lung carcinomas resected with curative intent. "
10/01/1993 - "We therefore concluded that NCAM expression in non-small-cell lung cancer is correlated to nodal status and that it indicates a poor prognosis. "
10/01/1993 - "Patients with NCAM-positive non-small-cell lung cancer proved to have a shorter survival than those with NCAM-negative disease. "
|3.||Kainic Acid (Kainate)
|7.||Neural Cell Adhesion Molecules (Neural Cell Adhesion Molecule)
|9.||polysialyl neural cell adhesion molecule
|10.||Protein Isoforms (Isoforms)
|1.||Drug Therapy (Chemotherapy)
|3.||Heterologous Transplantation (Xenotransplantation)