|1.||Freedman, Barry I: 12 articles (01/2013 - 10/2008)|
|2.||Tajsharghi, Homa: 7 articles (06/2014 - 02/2004)|
|3.||Oldfors, Anders: 7 articles (06/2014 - 02/2004)|
|4.||Langefeld, Carl D: 7 articles (01/2013 - 01/2009)|
|5.||Divers, Jasmin: 7 articles (12/2011 - 10/2008)|
|6.||Ohnuki, Yoshiki: 6 articles (01/2015 - 06/2005)|
|7.||Saeki, Yasutake: 6 articles (01/2015 - 06/2005)|
|8.||Bowden, Donald W: 6 articles (01/2013 - 04/2009)|
|9.||Winkler, Cheryl A: 6 articles (01/2013 - 10/2008)|
|10.||Savoia, Anna: 5 articles (01/2016 - 04/2004)|
07/01/2012 - "Interstitial fibrosis, poorly organized myofibrils, and swollen mitochondria with loss of cristae were improved in the myocardium of α-myosin heavy chain (MHC)-cTnT(R141W)×CYP2E1-silence double-transgenic mice when compared with the cTnT(R141W) transgenic mice. "
01/01/2010 - "The majority of the subscapularis muscle biopsy samples had an essentially normal morphology and showed a predominance of type I myosin heavy chain isoform, while one biopsy showed signs of marked fibrosis and a predominance of type II myosin heavy chain isoform. "
10/01/2015 - "Diaphragm morphology revealed increased fibrosis (P < 0.0001), atrophy (P < 0.0001), and reduced myosin heavy-chain content (P < 0.001), compared with lean controls. "
09/01/2015 - "Both ITO and Ex developed cardiomyocyte hypertrophy without fibrosis, no overexpression of osteopontin-1 or β-myosin heavy chain, and increased expression of sarcoplasmic reticulum Ca(2+) protein. "
03/01/2013 - "In OPMD patient CPM (n = 6), there were typical dystrophic features with extensive endomysial fibrosis and marked atrophy of myosin heavy-chain IIa fibers. "
|2.||Cardiomegaly (Heart Hypertrophy)
03/01/2008 - "It has been demonstrated in animal studies that disruption of the Irx4 gene causes inhibition of chamber-specific expression of myosin heavy chain genes, resulting in abnormal ventricular gene expression and cardiac hypertrophy. "
08/01/2005 - "Mice mutant in myosin heavy chain develop significant cardiac hypertrophy at young adult age. "
07/01/2003 - "Increased atrial natriuretic peptide and myosin heavy chain expression demonstrated activation of the molecular program for cardiac hypertrophy. "
11/01/1997 - "To explore the molecular basis of cardiac hypertrophy, we have analyzed the regulation of myosin heavy chain gene (MHC) expression. "
09/01/1997 - "In hypertensive cardiac hypertrophy, myosin heavy chain isoform shift and reduction of SR protein levels are related to systolic and diastolic dysfunction, respectively. "
01/01/2004 - "The purpose of this study was to investigate the effect of compensatory hypertrophy (CH), heavy-resistance exercise training (HRET), and simultaneous CH and HRET on fast-twitch skeletal-muscle myofibrillar-protein synthesis, myosin heavy-chain (MHC) turnover rate, and MHC-isoform composition in young and old rats. "
01/01/2014 - "This was associated with mitigating the hypertrophy-associated gene signature, including reversing the myosin heavy chain isoform switch but in a pattern distinguishable from that associated with neovascularization-induced reversal. "
09/20/2013 - "Role of masseter muscle β₂-adrenergic signaling in regulation of muscle activity, myosin heavy chain transition, and hypertrophy."
07/23/2013 - "In contrast, markers of pathological hypertrophy remain unchanged (β-myosin heavy chain, skeletal α-actin, atrial natriuretic peptide). "
09/02/2011 - "Induction of the fetal hypertrophic marker gene β-myosin heavy chain (β-MyHC) is a signature feature of pressure overload hypertrophy in rodents. "
07/01/2015 - "To explore the effect of Salvianolate on myosin heavy chain (MHC) in cardiomyocytes of congestive heart failure (CHF) rats. "
07/01/2015 - "[Effects of Salvianolate on Myosin Heavy Chain in Cardiomyocytes of Congestive Heart Failure Rats]."
04/01/2015 - "Antithetical regulation of α-myosin heavy chain between fetal and adult heart failure though shuttling of HDAC5 regulating YY-1 function."
01/01/2015 - "Mice lacking both IRS1 and IRS2 in adult hearts exhibited severe heart failure and a remarkable increase in the β-isoform of myosin heavy chain (β-MHC) gene expression, whereas deletion of cardiac Foxo1 gene largely prevented the heart failure and resulted in a decrease in β-MHC expression. "
01/01/2014 - "Intracellular signaling pathways involved in skeletal myosin heavy chain (MyHC) isoform alterations during heart failure (HF) are not completely understood. "
01/01/1996 - "The purpose of this study was to investigate whether the soleus muscle undergoes atrophy and alterations in myosin heavy chain (MHC) composition during non-weight bearing in the absence of synergists. "
09/15/2015 - "Hindlimb suspension (HLS) induced significant myofiber type-specific atrophy in myosin heavy chain (MHC) IIx (P < 0.05) and MHC IIb myofibers (P < 0.05). "
06/01/2015 - "Myosin heavy chain IIAX fibers were more prevalent in the OA group, and their atrophy was sex-specific: men showed a reduction in cross-sectional area, and women showed no differences. "
01/01/2015 - "We examined the effect of CB on DEX-induced masseter muscle atrophy by measuring masseter muscle weight, fiber diameter, cross-sectional area, and myosin heavy chain (MHC) composition. "
01/01/2015 - "Aerobic high-intensity interval training (HIT) improves cardiovascular capacity but may reduce the finite work capacity above critical power (W') and lead to atrophy of myosin heavy chain (MyHC)-2 fibers. "
|1.||Messenger RNA (mRNA)
|2.||Adenosine Triphosphatases (ATPase)
|3.||Protein Isoforms (Isoforms)
|4.||Proteins (Proteins, Gene)
|5.||Atrial Natriuretic Factor (ANF)
|7.||Reactive Oxygen Species (Oxygen Radicals)
|2.||Vertical Dimension (Occlusion Vertical Dimension)
|3.||Fat-Restricted Diet (Diet, Fat Restricted)
|4.||Heart Transplantation (Grafting, Heart)