|1.||Fujinami, Robert S: 4 articles (07/2014 - 01/2007)|
|2.||Waldner, Hanspeter: 4 articles (02/2013 - 04/2004)|
|3.||Tsunoda, Ikuo: 4 articles (01/2013 - 01/2007)|
|4.||Greer, Judith M: 4 articles (11/2008 - 06/2004)|
|5.||Kuchroo, Vijay K: 4 articles (10/2007 - 04/2004)|
|6.||Libbey, Jane E: 3 articles (07/2014 - 11/2008)|
|7.||Edgar, Julia M: 3 articles (11/2013 - 07/2004)|
|8.||Pender, Michael P: 3 articles (11/2008 - 06/2004)|
|9.||Sobel, Raymond A: 3 articles (10/2007 - 07/2004)|
|10.||Reddy, Jayagopala: 3 articles (10/2007 - 07/2004)|
|1.||Demyelinating Diseases (Demyelinating Disease)
09/01/2007 - "This study is the first to systematically assess hippocampal demyelination in MS. Hippocampal tissue samples of 19 chronic MS cases and 7 controls with non-neurologic disease were stained immunohistochemically for myelin proteolipid protein. "
07/01/2001 - "To study the potential of virus-induced molecular mimicry to initiate autoimmune demyelination, a nonpathogenic TMEV variant was engineered to encode a 30-mer peptide encompassing the immunodominant encephalitogenic myelin proteolipid protein (PLP139-151) epitope. "
04/03/2000 - "Lymphocytes from mice chronically infected with Theiler's murine encephalomyelitis virus produce demyelination of organotypic cultures after stimulation with the major encephalitogenic epitope of myelin proteolipid protein. "
04/01/1997 - "Collectively, these results indicate that myelin proteolipid protein peptide-specific CD8+ CTL may be an important source of proinflammatory soluble mediators that could promote and mediate the inflammatory response in MS demyelination."
03/01/1995 - "In 7-month-old animals that appear to be undergoing demyelination in the CNS, both the major myelin proteolipid protein and DM-20 are greatly reduced relative to the 2-month-old animal. "
|2.||Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
07/01/2014 - "In this study, relapsing-remitting experimental autoimmune encephalomyelitis was induced through active immunization of SJL/J mice with a myelin proteolipid protein peptide. "
12/29/2009 - "To test this hypothesis, SJL/J mice (n=21) were subjected to experimental autoimmune encephalomyelitis (EAE), an animal model of MS. EAE mice were treated with saline or Tbeta4 (6 mg/kg, n=10) every 3 days starting on the day of myelin proteolipid protein (PLP) immunization for total five doses. "
11/15/2008 - "Targeting myelin proteolipid protein to the MHC class I pathway by ubiquitination modulates the course of experimental autoimmune encephalomyelitis."
04/05/2005 - "Finally, we show that myelin proteolipid protein-specific autoreactive T cells transduced with Foxp3 cannot mediate experimental autoimmune encephalomyelitis, providing further support that Foxp3 suppresses the effector function of autoreactive T cells. "
03/01/2005 - "The role of the blood-brain barrier (BBB) in determining lesion distribution was assessed in an atypical model of experimental autoimmune encephalomyelitis (EAE) induced in C3H/HeJ mice by immunisation with peptide 190-209 of myelin proteolipid protein, which can result in two distinct types of EAE, each with distinct lesion distribution. "
09/01/2005 - "To study the effects of a point mutation found in Pelizaeus-Merzbacher disease (PMD) on the physicochemical and structural properties of the extracellular loop 4 of the myelin proteolipid protein (PLP), we synthesized the peptide PLP(181-230)Pro215 and one mutant PLP(181-230)Ser215 with regioselective formation of the two disulphide bridges Cys200-Cys219 and Cys183-Cys227. "
09/01/2012 - "Overexpression of the major myelin proteolipid protein (PLP) is detrimental to brain development and function and is the most common cause of Pelizaeus-Merzbacher disease. "
11/01/2009 - "Missense mutations in human PLP1, the gene encoding myelin proteolipid protein (PLP), cause dysmyelinating Pelizaeus-Merzbacher disease of varying severity. "
01/01/2009 - "PMD (Pelizaeus-Merzbacher disease), a CNS (central nervous system) disease characterized by shortened lifespan and severe neural dysfunction, is caused by mutations of the PLP1 (X-linked myelin proteolipid protein) gene. "
09/01/2005 - "Synthesis and secondary structure of loop 4 of myelin proteolipid protein: effect of a point mutation found in Pelizaeus-Merzbacher disease."
11/01/2008 - "Myelin proteolipid protein: an effective autoantigen and target of autoimmunity in multiple sclerosis."
11/01/2000 - "We have previously shown that patients with multiple sclerosis (MS) have increased T cell responses to the immunodominant region (residues 184-209) of myelin proteolipid protein (PLP). "
11/01/2000 - "Surges of increased T cell reactivity to an encephalitogenic region of myelin proteolipid protein occur more often in patients with multiple sclerosis than in healthy subjects."
04/15/1998 - "Myelin proteolipid protein (PLP) is a prime candidate autoantigen for multiple sclerosis. "
05/01/1992 - "T cell sensitization to two myelin components, myelin basic protein (MBP) and myelin proteolipid protein (PLP), may be important to the pathogenesis of multiple sclerosis (MS). "
05/03/1999 - "Infection with a recombinant vaccinia virus encoding myelin proteolipid protein causes suppression of chronic relapsing-remitting experimental allergic encephalomyelitis."
01/01/1995 - "The present study also shows that a restricted infection of oligodendrocytes with CDV down-regulates the transcription of the major myelin genes coding for proteolipid protein, myelin basic protein (MBP) and myelin-associated glycoprotein in a very similar way. "
12/01/2012 - "In a novel animal model of MS, SJL/J mice primed through infection with a recombinant vaccinia virus (VV) encoding myelin proteolipid protein (PLP) (VV(PLP)) were susceptible to a central nervous system (CNS) inflammatory disease following administration of a nonspecific immunostimulant [complete Freund's adjuvant (CFA) plus Bordetella pertussis (BP)]. "
07/01/2005 - "Our previous reports showed that the infection of SJL mice with a nonpathogenic variant of Theiler's murine encephalomyelitis virus (TMEV) engineered to express a naturally occurring Haemophilus influenzae-encoded molecular mimic (HI574-586) of an immunodominant self-myelin proteolipid protein epitope (PLP139-151) induced a rapid-onset demyelinating disease associated with the activation of PLP139-151-specific Th1 responses. "
|3.||Myelin-Associated Glycoprotein (S-MAG)
|4.||T-Lymphocyte Epitopes (Epitopes, T Lymphocyte)
|5.||Fatty Acids (Saturated Fatty Acids)
|1.||Surgical Instruments (Clip)