|1.||Mohan, S: 6 articles (02/2006 - 02/2000)|
|2.||Yasuoka, Hidekata: 5 articles (01/2014 - 09/2006)|
|3.||Feghali-Bostwick, Carol A: 5 articles (01/2014 - 09/2006)|
|4.||Zhang, Wei: 4 articles (01/2009 - 03/2004)|
|5.||Tanno, Barbara: 4 articles (12/2006 - 06/2002)|
|6.||Mancini, Camillo: 4 articles (12/2006 - 06/2002)|
|7.||Vitali, Roberta: 4 articles (12/2006 - 06/2002)|
|8.||Raschellà, Giuseppe: 4 articles (12/2006 - 06/2002)|
|9.||Yamaguchi, Yukie: 3 articles (01/2014 - 01/2008)|
|10.||Amaar, Yousef G: 3 articles (01/2014 - 04/2002)|
|1.||Wounds and Injuries (Trauma)
12/01/2013 - "IGFBP-5, in contrast, enhanced both cell-cell and cell-ECM adhesion and also improved wound closure in epithelial cells whereas, in mesenchymal cells, IGFBP-5 decreased adhesion and migration. "
01/01/1999 - "Later in the wounding response, levels of IGF-II decline in the CSF and the wound neuropil, possibly with the aid of increased IGFBP-5 levels that may help to locally sequester and down-regulate IGF-II activity. "
02/15/2013 - "IGF-I enhanced scrape-wound closure in keratinocytes whereas IGFBP-5 inhibited this response. "
02/15/2013 - "Further, the IGF-I to IGFBP-5 ratio is altered in diabetic skin, where wound closure is impaired. "
02/15/2013 - "We investigated whether Gap27 remains effective in augmenting scrape-wound closure in human skin wound models simulating diabetes-induced changes, using culture conditions with raised glucose, insulin and IGFBP-5. "
01/01/2010 - "IGFBP-5 Metabolism Is Disrupted in the Rat Medial Meniscal Tear Model of Osteoarthritis."
01/01/2009 - "MMP-13 and IGFBP-5 are important factors involved in osteoarthritis (OA). "
09/01/2004 - "Increased matrix concentrations of IGFBP-5 in cancellous bone in osteoarthritis."
05/01/1998 - "We conclude that locally produced IGFBPs, in particular IGFBP-5, may play a critical role in the regulation of cartilage matrix degradation in inflammatory and degenerative arthritides."
03/01/2002 - "Inhibition of insulin-like growth factor binding protein 5 proteolysis in articular cartilage and joint fluid results in enhanced concentrations of insulin-like growth factor 1 and is associated with improved osteoarthritis."
10/01/1998 - "Serum starvation provoked (i) apoptosis of granulosa cells within 48 hr, (ii) a marked decrease in cell density, and (iii) a marked increase in the amount of IGFBP-5 associated with cell membranes and with the walls of culture wells, but no change in culture medium. "
10/01/1998 - "The increase in the amount of cell- and wall-associated IGFBP-5 after serum starvation was essentially due to the consecutive decrease in cell density rather than to an increase in cell apoptosis. "
10/01/2006 - "Starvation had no effect on liver IGFBP-2 and IGFBP-6 mRNA abundance, whereas refeeding provoked a peak of IGFBP-2 and IGFBP-6 expression at day 7. In muscle, starvation led to a decrease of the IGFBP-2 mRNA level, which was restored only from day 7. IGFBP-4 mRNA abundance in starved fish was lower than in the controls and refeeding led to a transient upregulation (sevenfold) of IGFBP-4 gene at day 1. IGF-I, IGFBP-5, and IGFBP-related protein 1 (rP1) expression profiles were similar, showing a decrease of expression after starvation, a first peak of expression at day 2, a second peak at day 7, and a return to normal value from day 15. "
|4.||Breast Neoplasms (Breast Cancer)
01/01/2014 - "We here aimed to determine the association between PIK3CA gene mutations and IGFBP-5 expressions for the first time in breast cancer patients. "
01/01/2014 - "Detection of PIK3CA gene mutations with HRM analysis and association with IGFBP-5 expression levels in breast cancer."
03/15/2012 - "IGFBP-5 expression is a marker of poor outcome in patients with breast cancer. "
03/15/2012 - "To improve the significance of insulin-like growth factor-binding protein 5 (IGFBP-5) as a prognostic and potentially predictive marker in patients with breast cancer. "
01/01/2008 - "Multifunctional roles of insulin-like growth factor binding protein 5 in breast cancer."
|5.||Osteosarcoma (Osteogenic Sarcoma)
02/01/2008 - "Supression of IGFBP-5 expression inhibited proliferation of Huh-7 cells as well as U-2 OS osteosarcoma cells. "
08/01/2005 - "IGFBP-5 was used as bait in a yeast two-hybrid screen of a human osteosarcoma cDNA library. "
04/05/2002 - "We therefore undertook studies to identify proteins that bind to IGFBP-5 using IGFBP-5 as bait in a yeast two-hybrid screen of a U2 human osteosarcoma cDNA library. "
02/01/2006 - "We evaluated the expression of IGFBP-5, FHL-2, and ADAM-9 by real-time reverse transcriptase (RT)-PCR during differentiation of mouse bone marrow stromal cells into osteoblasts and in response to treatment with bone formation modulators in the LSaOS human osteosarcoma cell line. "
09/10/1999 - "Progesterone (PG) increased IGFBP-5 expression in normal human osteoblasts and increased IGFBP-5 transcription in U2 human osteosarcoma cells. "
|3.||Insulin-Like Growth Factor II (Somatomedin A)
|4.||Messenger RNA (mRNA)
|5.||Insulin-Like Growth Factor Binding Protein 3
|6.||Insulin-Like Growth Factor Binding Protein 4
|7.||Conditioned Culture Media
|8.||Insulin-Like Growth Factor I (IGF-1)
|9.||Carrier Proteins (Binding Protein)
|10.||Insulin-Like Growth Factor Binding Protein 2
|2.||Heterologous Transplantation (Xenotransplantation)
|3.||Mammaplasty (Breast Reconstruction)