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CD59 Antigens

Small glycoproteins found on both hematopoietic and non-hematopoietic cells. CD59 restricts the cytolytic activity of homologous complement by binding to C8 and C9 and blocking the assembly of the membrane attack complex. (From Barclay et al., The Leukocyte Antigen FactsBook, 1993, p234)
Also Known As:
CD59 Antigen; Membrane Inhibitor of Reactive Lysis; Antigens, CD59; HRF20; Homologous Restriction Factor 20; MACIF; Membrane Attack Complex Inhibition Factor; Protectin
Networked: 109 relevant articles (3 outcomes, 6 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Serhan, Charles N: 8 articles (01/2021 - 01/2009)
2. Shay, Ashley E: 2 articles (01/2021 - 12/2019)
3. Hao, Yu: 2 articles (01/2020 - 04/2018)
4. Jin, Sheng-Wei: 2 articles (01/2020 - 04/2018)
5. Aursnes, Marius: 2 articles (11/2017 - 04/2016)
6. Dalli, Jesmond: 2 articles (11/2017 - 04/2016)
7. Hansen, Trond V: 2 articles (11/2017 - 04/2016)
8. Navolotskaia, E V: 2 articles (01/2011 - 07/2009)
9. Sadovnikov, V B: 2 articles (01/2011 - 07/2009)
10. Altomonte, M: 2 articles (12/2000 - 05/2000)

Related Diseases

1. Neoplasms (Cancer)
2. Inflammation (Inflammations)
3. Leukemia
4. Virus Diseases (Viral Diseases)
5. Melanoma (Melanoma, Malignant)

Related Drugs and Biologics

1. CD55 Antigens (Decay Accelerating Factor)
2. Complement System Proteins (Complement)
3. Proteins (Proteins, Gene)
4. Lipoxins
5. Complement Membrane Attack Complex (Membrane Attack Complex)
6. Membrane Cofactor Protein
7. Monoclonal Antibodies
8. Complement Receptors (Complement Receptor)
9. Syndecan-4
10. Integrin beta3 (GPIIIa)

Related Therapies and Procedures

1. Peripheral Blood Stem Cell Transplantation (Peripheral Stem Cell Transplantation)
2. Drug Therapy (Chemotherapy)
3. Immunotherapy
4. Intravenous Administration
5. Therapeutics