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Persian Gulf Syndrome (Gulf War Syndrome)

Unexplained symptoms reported by veterans of the Persian Gulf War with Iraq in 1991. The symptoms reported include fatigue, skin rash, muscle and joint pain, headaches, loss of memory, shortness of breath, gastrointestinal and respiratory symptoms, and extreme sensitivity to commonly occurring chemicals. (Nature 1994 May 5;369(6475):8)
Also Known As:
Gulf War Syndrome; Syndrome, Gulf War; Syndrome, Persian Gulf
Networked: 64 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Chronic Fatigue Syndrome (Myalgic Encephalomyelitis)
2. Fatigue
3. Sudden Infant Death (SID)
4. Fibromyalgia (Fibrositis)
5. Sick Building Syndrome

Experts

1. Shoenfeld, Yehuda: 4 articles (04/2013 - 02/2007)
2. Staines, Donald R: 4 articles (01/2005 - 01/2004)
3. Jara, Luis J: 2 articles (04/2013 - 04/2013)
4. Israeli, Eitan: 2 articles (01/2013 - 06/2011)
5. Agmon-Levin, Nancy: 2 articles (01/2013 - 02/2011)
6. Staines, Donald: 2 articles (01/2005 - 01/2005)
7. Henderson, Rogene F: 2 articles (10/2002 - 10/2002)
8. Abou-Donia, Mohamed B: 2 articles (08/2002 - 03/2002)
9. Petty, F: 2 articles (06/2001 - 09/2000)
10. Haley, R W: 2 articles (06/2001 - 09/2000)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Persian Gulf Syndrome:
1. Pyridostigmine Bromide (Pyridostigmine)FDA LinkGeneric
2. ButyrylcholinesteraseIBA
3. AcetylcholinesteraseIBA
4. Permethrin (Ambush)FDA LinkGeneric
5. DEET (DET)IBA
6. Hazardous Substances (Hazardous Materials)IBA
7. Macrophagic myofasciitisIBA
04/01/2013 - "Recently, a new syndrome was introduced, autoimmune/inflammatory syndrome induced by adjuvants (ASIA), that includes postvaccination phenomena, macrophagic myofasciitis, Gulf War syndrome and siliconosis. "
01/01/2013 - "ASIA syndrome, "Autoimmune (Auto-inflammatory) Syndromes Induced by Adjuvants" includes at least four conditions which share a similar complex of signs and symptoms and have been defined by hyperactive immune responses: siliconosis, macrophagic myofasciitis syndrome, Gulf war syndrome and post-vaccination phenomena. "
02/01/2012 - "In recent years, four conditions, siliconosis, Gulf War syndrome (GWS), macrophagic myofasciitis syndrome (MMF) and post-vaccination phenomena, were linked to a previous exposure to an adjuvant, suggesting a common denominator, and it has been proposed to incorporate comparable conditions under a common syndrome entitled Autoimmune/inflammatory Syndrome Induced by Adjuvants (ASIA). "
02/01/2011 - "In recent years, four conditions: siliconosis, the Gulf war syndrome (GWS), the macrophagic myofasciitis syndrome (MMF) and post-vaccination phenomena were linked with previous exposure to an adjuvant. "
01/01/2011 - "Recently, Shoenfeld and Agmon-Levin described a potential new syndrome, namely ASIA - autoimmune/inflammatory syndrome induced by adjuvants, that comprises four medical conditions: siliconosis, the Gulf war syndrome, the macrophagic myofasciitis syndrome and post-vaccination phenomena, characterized by hyperactive immune responses accompanied by a similar complex of signs and symptoms. "
8. SqualeneIBA
9. SiliconesIBA
08/01/2000 - "The authors focus their discussion on three problems (painter's encephalopathy, silicone breast implant neurotoxicity, and the Gulf War syndrome) for which no scientific consensus has been reached that would establish them as diagnosable disorders. "
06/01/2011 - "In the 1990s the term "functional somatic syndromes" was applied to several syndromes, including SBS, multiple chemical sensitivity, repetition stress injury, the side effects of silicone breast implants, the Gulf War syndrome (GWS), chronic fatigue syndrome, the irritable bowel syndrome, and fibromyalgia. "
06/01/1999 - "These syndromes include multiple chemical sensitivity, the sick building syndrome, repetition stress injury, the side effects of silicone breast implants, the Gulf War syndrome, chronic whiplash, the chronic fatigue syndrome, the irritable bowel syndrome, and fibromyalgia. "
11/01/2009 - "The debatable question of silicone as an adjuvant and connective tissue diseases, as well as the Gulf War syndrome and macrophagic myofaciitis which followed multiple injections of aluminium-based vaccines, are presented here. "
08/01/2003 - "Overlapping symptom complexes suggest that chronic fatigue syndrome, Gulf war syndrome, premenstrual syndrome, post traumatic stress disorder, breast implant silicone sensitivity syndrome, bipolar affective disorder, systemic candidiasis, myofascial pain syndrome, and idiopathic environmental intolerance are similar enough to fibromyalgia to merit investigation for possible thyroid resistance. "
10. NeuropeptidesIBA

Therapies and Procedures

1. Breast Implants (Breast Implant)
08/01/2000 - "The authors focus their discussion on three problems (painter's encephalopathy, silicone breast implant neurotoxicity, and the Gulf War syndrome) for which no scientific consensus has been reached that would establish them as diagnosable disorders. "
12/01/2000 - "Rheumatologists grapple in daily practice with many controversial syndromes including fibromyalgia, late whiplash syndrome, chronic fatigue syndrome, Gulf War syndrome, the adverse outcomes of silicon breast implants and so on. "
06/01/2011 - "In the 1990s the term "functional somatic syndromes" was applied to several syndromes, including SBS, multiple chemical sensitivity, repetition stress injury, the side effects of silicone breast implants, the Gulf War syndrome (GWS), chronic fatigue syndrome, the irritable bowel syndrome, and fibromyalgia. "
06/01/1999 - "These syndromes include multiple chemical sensitivity, the sick building syndrome, repetition stress injury, the side effects of silicone breast implants, the Gulf War syndrome, chronic whiplash, the chronic fatigue syndrome, the irritable bowel syndrome, and fibromyalgia. "
08/01/2003 - "Overlapping symptom complexes suggest that chronic fatigue syndrome, Gulf war syndrome, premenstrual syndrome, post traumatic stress disorder, breast implant silicone sensitivity syndrome, bipolar affective disorder, systemic candidiasis, myofascial pain syndrome, and idiopathic environmental intolerance are similar enough to fibromyalgia to merit investigation for possible thyroid resistance. "
2. Injections
3. Transcutaneous Electric Nerve Stimulation (TENS)