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Ischemic Optic Neuropathy (Anterior Ischemic Optic Neuropathy)

Ischemic injury to the OPTIC NERVE which usually affects the OPTIC DISK (optic neuropathy, anterior ischemic) and less frequently the retrobulbar portion of the nerve (optic neuropathy, posterior ischemic). The injury results from occlusion of arterial blood supply which may result from TEMPORAL ARTERITIS; ATHEROSCLEROSIS; COLLAGEN DISEASES; EMBOLISM; DIABETES MELLITUS; and other conditions. The disease primarily occurs in the sixth decade or later and presents with the sudden onset of painless and usually severe monocular visual loss. Anterior ischemic optic neuropathy also features optic disk edema with microhemorrhages. The optic disk appears normal in posterior ischemic optic neuropathy. (Glaser, Neuro-Ophthalmology, 2nd ed, p135)
Also Known As:
Anterior Ischemic Optic Neuropathy; Posterior Ischemic Optic Neuropathy; Optic Neuropathy, Ischemic; Optic Neuropathy, Anterior Ischemic; Optic Neuropathy, Posterior Ischemic; Ischaemic Neuropathy, Optic; Ischemia, Optic Nerve; Ischemic Neuropathy, Optic; Ischemic Optic Neuropathies; Nerve Ischemia, Optic; Neuropathy, Ischemic Optic; Neuropathy, Optic Ischaemic; Neuropathy, Optic Ischemic; Optic Ischaemic Neuropathies; Optic Ischemic Neuropathies; Optic Nerve Ischemias; NAION; Nonarteritic Anterior Ischemic Optic Neuropathy; Optic Ischaemic Neuropathy; Optic Ischemic Neuropathy; Optic Nerve Ischemia
Networked: 1025 relevant articles (64 outcomes, 133 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Ischemic Optic Neuropathy (Anterior Ischemic Optic Neuropathy)
2. Optic Nerve Diseases (Optic Neuropathy)
3. Optic Neuritis (Retrobulbar Neuritis)
4. Retinal Artery Occlusion
5. Leber Hereditary Optic Atrophy (Leber's Hereditary Optic Neuropathy)

Experts

1. Tsai, Rong-Kung: 19 articles (05/2022 - 01/2014)
2. Bernstein, Steven L: 15 articles (12/2021 - 10/2007)
3. Wen, Yao-Tseng: 14 articles (05/2022 - 01/2016)
4. Guo, Yan: 13 articles (12/2021 - 10/2007)
5. Hayreh, Sohan Singh: 10 articles (12/2019 - 09/2004)
6. Liao, Yaping Joyce: 9 articles (12/2022 - 09/2013)
7. Miller, Neil R: 9 articles (01/2021 - 04/2010)
8. Huang, Tzu-Lun: 9 articles (01/2020 - 01/2014)
9. Micieli, Jonathan A: 8 articles (09/2022 - 05/2017)
10. Huang, Shun-Ping: 8 articles (02/2022 - 01/2014)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Ischemic Optic Neuropathy:
1. SteroidsIBA
2. Adrenal Cortex Hormones (Corticosteroids)IBA
3. Levodopa (L Dopa)FDA LinkGeneric
4. Retinaldehyde (Retinal)IBA
5. Triamcinolone Acetonide (Azmacort)FDA LinkGeneric
6. Alprostadil (Muse)FDA LinkGeneric
7. Oxygen (Dioxygen)IBA
8. Granulocyte Colony-Stimulating Factor (G-CSF)IBA
9. GlucocorticoidsIBA
10. Ranibizumab (Lucentis)FDA Link

Therapies and Procedures

1. Decompression
2. Therapeutics
3. Intravitreal Injections
4. Aftercare (After-Treatment)
5. Hemodilution