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src Homology Domains

Regions of AMINO ACID SEQUENCE similarity in the SRC-FAMILY TYROSINE KINASES that fold into specific functional tertiary structures. The SH1 domain is a CATALYTIC DOMAIN. SH2 and SH3 domains are protein interaction domains. SH2 usually binds PHOSPHOTYROSINE-containing proteins and SH3 interacts with CYTOSKELETAL PROTEINS.
Also Known As:
src Homology Region 2 Domain; Homology Domain, src; Homology Domains, src; SH Domain; SH1 Domains; SH2 Domains; SH3 Domains; src Homology Domain; SH Domains; SH1 Domain; SH2 Domain; SH3 Domain
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Context: Research Results