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Inflammation Mediators

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The endogenous compounds that mediate inflammation (AUTACOIDS) and related exogenous compounds including the synthetic prostaglandins (PROSTAGLANDINS, SYNTHETIC).

Also Known As:

Mediators, Inflammation; Mediators of Inflammation

Networked: 504 relevant articles (9 outcomes, 45 trials/studies) for this Bio-Agent, Comments

Relationship Network

Bio-Agent Context: Research Results

Biological Factors: 930
- Inflammation Mediators: 504

Experts

1.	Cuzzocrea, Salvatore: 5 articles (09/2008 - 07/2005)
2.	Mazzon, Emanuela: 4 articles (09/2008 - 08/2005)
3.	Genovese, Tiziana: 4 articles (09/2008 - 08/2005)
4.	Di Paola, Rosanna: 4 articles (09/2008 - 08/2005)
5.	Stein, C Michael: 3 articles (11/2009 - 07/2008)
6.	Shintani, Ayumi: 3 articles (11/2009 - 07/2008)
7.	Raggi, Paolo: 3 articles (11/2009 - 07/2008)
8.	Oeser, Annette: 3 articles (11/2009 - 07/2008)
9.	Gebretsadik, Tebeb: 3 articles (11/2009 - 07/2008)
10.	Chung, Cecilia P: 3 articles (11/2009 - 07/2008)

Related Diseases

1.	Inflammation 01/01/2008 - "Inflammation is an adaptive response to damage of vascularized tissues, which develops according to a stereotyped sequence governed by the local production of the so-called "chemical mediators of inflammation". " 01/01/2006 - "Indeed, as mediators of inflammation are multiple, the strategy of identifying triggers and mechanisms of inflammation in each special clinical setting and directing treatment at the special triggers or to rate limiting steps in effector pathways appears more reasonable or a promising strategy." 05/01/2004 - "In addition to the identification of new regulatory mechanisms of the coagulation system and of an explosive number of mediators of inflammation, it is now clear that the existence of a positive feed-back between inflammation and coagulation leads to reciprocal activation of both pathways. " 09/01/2003 - "Respiratory tract inflammation, production of mediators of inflammation capable of reaching the brain, systemic circulation of PM, and disruption of the nasal respiratory and olfactory barriers are likely in these populations. " 12/01/2002 - "Searches for chemical mediators of inflammation underlying classical signs of inflammation i.e. " Order ALL the reference details at left...
2.	Rheumatoid Arthritis 04/01/1991 - "Total fasting results in improvement in rheumatoid arthritis, but appears to be mediated by diminution in production of chemical mediators of inflammation, rather than by elimination of a dietary allergen. " 12/01/2009 - "Herbal medicinal products (HMPs) that interact with the mediators of inflammation are used in the treatment of rheumatoid arthritis (RA). " 07/01/2007 - "OBJECTIVE: Macrophages are the major source of inflammation mediators that are important in the pathogenesis of rheumatoid arthritis (RA). " 12/01/2006 - "OBJECTIVE: To investigate extensively the features of cell infiltration and expression of mediators of inflammation and joint destruction in the synovium of patients with PsA compared with patients with rheumatoid arthritis matched for disease duration and use of drugs. " 08/01/2003 - "New treatment strategies in rheumatoid arthritis are targeted to interfere with critical mediators of inflammation. " Order ALL the reference details at left...
3.	Hypersensitivity (Allergy) 07/01/2006 - "CONCLUSION: MMP-9 and MMP-2 are mediators of inflammation in the OME; in addition, MMP-9 may play a significant role in the pathophysiology of OME with allergy." 01/01/1989 - "Nasal hypersensitivity is defined by an exaggerated response to certain specific stimuli such as a work-related agent, non-specific stimuli (irritant effect), or to allergic or inflammation mediators. " 01/01/1989 - "Nasal hypersensitivity is defined by an exaggerated response to certain specific stimuli such as a work-related agent, non-specific stimuli (irritant effect), or to allergic or inflammation mediators. " 05/01/1986 - "It is our hypothesis that allergy and other pathophysiologic events that release or generate mediators of inflammation in the nasopharynx play a role in the pathogenesis of middle ear diseases.(ABSTRACT TRUNCATED AT 250 WORDS)" 08/12/1983 - "Thus, the epithelium may be an important source of mediators of inflammation and hypersensitivity of pulmonary airways." Order ALL the reference details at left...
4.	Thrombosis (Thrombus) 01/01/2008 - "Historically, platelets were viewed as simple anucleate cells responsible for initiating thrombosis and maintaining hemostasis, but clearly they are also key mediators of inflammation and immune cell activation. " 07/01/2007 - "AT(1)R-AA stimulate AT(1)R and induce mediators of inflammation and thrombosis. " 07/01/1998 - "Evidence suggests that mediators of inflammation are not only instrumental in the formation of plaque but may also be involved in the rapid progression of atheromatous lesions leading to plaque fissuring, endothelial injury, and intraluminal thrombosis. " 11/01/1997 - "Evidence suggests that mediators of inflammation not only are instrumental in the formation of plaque but also may be involved in the rapid progression of atheromatous lesions, leading to plaque fissuring and intraluminal thrombosis. " 01/01/2007 - "Venous valve disruption from the thrombus itself or thrombus-associated mediators of inflammation is considered to be a key initiating event for the development of venous hypertension that often underlies PTS. As existing treatments for PTS are extremely limited, strategies that focus on preventing the development of PTS in patients with DVT are more likely to be effective and cost-effective in reducing its burden. " Order ALL the reference details at left...
5.	Rhinitis 06/01/2004 - "Mediators of inflammation in the early and the late phase of allergic rhinitis." 01/01/1997 - "Similarities in symptoms, eosinophils and mediators of inflammation in the mucosa have been found between allergic rhinitis and sinusitis. " 06/01/1995 - "[Inflammation mediators (eosinophilic cationic protein, ECP) in a normal population and in patients with bronchial asthma or allergic rhinitis]" 12/01/1992 - "Once started, the allergic reaction includes the release of mediators of inflammation that produce well-known symptoms of allergic rhinitis. " 01/01/2001 - "The objective was to verify the efficacy of fluticasone propionate aqueous nasal spray in patients with allergic rhinitis; in a retrospective study, we have evaluated mediators of inflammation, making correlations with the clinical symptoms score during and outside the pollen season. " Order ALL the reference details at left...

Related Drugs and Biologics

1.	Interleukin-6 (Interleukin 6)
2.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
3.	Interleukin-1 (Interleukin 1)
4.	Interleukin-8 (Interleukin 8)
5.	Calcium
6.	Eosinophil Cationic Protein
7.	Arachidonic Acid (Vitamin F)
8.	Oxygen
9.	Free Radicals
10.	Phospholipases A2 (Phospholipase A2)

Related Therapies and Procedures

1.	Injections
2.	Low-Level Laser Therapy (LLLT)
3.	Lasers (Laser)
4.	Decompression
5.	Highly Active Antiretroviral Therapy (HAART)

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