Chaperonin 10

A group I chaperonin protein that forms a lid-like structure which encloses the non-polar cavity of the chaperonin complex. The protein was originally studied in BACTERIA where it is commonly referred to as GroES protein.

Also Known As:

GroES Protein; GroES Stress Protein; Heat-Shock Protein 10; hsp10 Protein; Heat Shock Protein 10; Heat Shock Proteins 10; Heat-Shock Proteins 10; hsp10 Family

Networked: 41 relevant articles (1 outcomes, 4 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Molecular Chaperones: 1279
    - Heat-Shock Proteins: 8088
      - Chaperonins: 222
        Group I Chaperonins: 1
        Chaperonin 10: 41
        early pregnancy factor: 27

Experts

1.	Siu, K W Michael: 5 articles (07/2007 - 05/2004)
2.	Colgan, Terence J: 4 articles (07/2007 - 05/2004)
3.	Romaschin, Alexander D: 4 articles (07/2007 - 05/2004)
4.	Fan, Songqing: 3 articles (01/2017 - 01/2017)
5.	Feng, Juan: 3 articles (01/2017 - 01/2017)
6.	Luo, Jiadi: 3 articles (01/2017 - 01/2017)
7.	Guo, Jingzhong: 3 articles (05/2005 - 05/2004)
8.	Rodrigues, Mary Joe: 3 articles (05/2005 - 05/2004)
9.	Chen, Lingjiao: 2 articles (01/2017 - 01/2017)
10.	Chu, Shuzhou: 2 articles (01/2017 - 01/2017)

Related Diseases

1.	Rheumatoid Arthritis 09/02/2006 - "Therapeutic efficacy and safety of chaperonin 10 in patients with rheumatoid arthritis: a double-blind randomised trial." 09/02/2006 - "Our aim was to establish whether chaperonin 10 is safe and effective in the treatment of rheumatoid arthritis. " 12/02/2006 - "Chaperonin 10 for rheumatoid arthritis." 12/02/2006 - "Chaperonin 10 for rheumatoid arthritis." 12/02/2006 - "Chaperonin 10 for rheumatoid arthritis."
2.	Neoplasms (Cancer) 05/01/2005 - "Using a commercially available quadrupole/TOF (QqTOF), we were able to resolve two potential cancer markers, subsequently identified off-line as chaperonin 10 and calgranulin A, that differ by 8 Da in mass. " 03/01/1999 - "To detect whether or not the early pregnancy factor (EPF)-like activity, or chaperonin 10, could be in the sera of patients with trophoblastic tumor in order to find another more efficient means to diagnose this kind of tumor. " 06/01/2013 - "Furthermore, a literature review shows that Heat shock protein 10 (Hsp10), single-stranded DNA-binding protein (SSBP1), and peptidyl-prolyl cis-trans isomerase A (PPIA), which were identified as being increased in the tumor samples in this study, may be closely related to protein folding and translation. " 05/01/2004 - "Protein expression profiling of endometrial malignancies reveals a new tumor marker: chaperonin 10." 03/01/2004 - "Confirmation by Northern blotting was performed for MAP kinase phosphatase-1, WDNM1 (extracellular proteinase inhibitor), Trop 2 (tumor-associated calcium signal transducer-2), procollagen type IV alpha, secretory leukoprotease inhibitor, prenylated snare protein Ykt6, ceruloplasmin and chaperonin 10. "
3.	Endometrial Neoplasms (Endometrial Cancer) 07/01/2006 - "The utility of IRMPD for the analysis of biological samples is demonstrated in a study of a recently identified potential marker for endometrial cancer, chaperonin 10." 05/01/2005 - "Calgranulin A, in combination with chaperonin 10 and other proteins, may eventually constitute a panel of markers to permit diagnosis and screening of endometrial cancer." 05/01/2005 - "A strategy for high-resolution protein identification in surface-enhanced laser desorption/ionization mass spectrometry: calgranulin A and chaperonin 10 as protein markers for endometrial carcinoma."
4.	Coronary Disease (Coronary Heart Disease) 12/01/2005 - "In this study the prevalence of antibodies against the heat shock protein 10 (HSP10) of Chamydophila pneumoniae (CP) (as assessed by ELISA) in patients with coronary heart disease (CHD) and seropositive or seronegative to CP, as assessed by microimmunofluorescence (MIF), was investigated. " 12/01/2005 - "Low prevalence of antibodies against heat shock protein 10 of Chlamydophila pneumoniae in patients with coronary heart disease."
5.	Tuberculosis (Tuberculoses) 04/01/2004 - "tuberculosis GroES protein in leprosy (n = 19) and tuberculosis (n = 9) patients and healthy endemic controls (n = 8). " 06/06/1995 - "tuberculosis chaperonin 10 and the MHC class I/II peptide binding cleft." 01/01/1999 - "tuberculosis chaperonin 10 enables the immune system to react against early abnormalities of virus-infected cells; this is accomplished by antibody cross-reacting with histones released during virus infection."

Related Drugs and Biologics

1.	Antibodies
2.	Cyclophilin A
3.	Antirheumatic Agents (DMARD)
4.	DNA-Binding Proteins (DNA Binding Protein)
5.	Proteins (Proteins, Gene)
6.	Chaperonin 60
7.	Calgranulin A
8.	Chaperonins
9.	Tumor Biomarkers (Tumor Markers)
10.	Dexlansoprazole

Related Therapies and Procedures

1.	Lasers (Laser)
2.	Oral Administration