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Dipeptidyl Peptidase 4 (Dipeptidyl Peptidase IV)

A serine protease that catalyses the release of an N-terminal dipeptide. Several biologically-active peptides have been identified as dipeptidyl peptidase 4 substrates including INCRETINS; NEUROPEPTIDES; and CHEMOKINES. The protein is also found bound to ADENOSINE DEAMINASE on the T-CELL surface and is believed to play a role in T-cell activation.
Also Known As:
Dipeptidyl Peptidase IV; Adenosine Deaminase Complexing Protein 2; CD26 Antigen; Antigen, CD26; Antigens, CD26; CD26 Antigens; Dipeptidyl-Peptidase IV
Networked: 524 relevant articles (20 outcomes, 42 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Sedo, Aleksi: 10 articles (01/2015 - 03/2004)
2. Reinhold, Dirk: 10 articles (01/2012 - 01/2006)
3. Kajiyama, Hiroaki: 10 articles (02/2010 - 05/2002)
4. Kikkawa, Fumitaka: 10 articles (02/2010 - 05/2002)
5. Ino, Kazuhiko: 10 articles (02/2010 - 05/2002)
6. Mizutani, Shigehiko: 10 articles (02/2010 - 05/2002)
7. Shibata, Kiyosumi: 10 articles (02/2010 - 05/2002)
8. Morimoto, Chikao: 9 articles (01/2014 - 09/2002)
9. Ansorge, Siegfried: 8 articles (01/2012 - 01/2006)
10. Ohnuma, Kei: 7 articles (01/2014 - 03/2005)

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1. Type 2 Diabetes Mellitus (MODY)
2. Myocardial Infarction
3. Inflammation
4. Diabetes Mellitus
5. Ischemia

Related Drugs and Biologics

1. sitagliptin (Januvia)
2. CD13 Antigens (Alanine Aminopeptidase)
3. Incretins
4. Glucagon-Like Peptide 1 (GLP 1)
5. vildagliptin
6. Peptide Hydrolases (Proteases)
7. Alkaline Phosphatase
8. Glucose (Dextrose)
9. Insulin (Novolin)
10. Metformin (Glucophage)

Related Therapies and Procedures

1. Transplants (Transplant)
2. Lasers (Laser)
3. Bariatric Surgery
4. Transplantation (Transplant Recipients)
5. Immunotherapy