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GABA Modulators

Substances that do not act as agonists or antagonists but do affect the GAMMA-AMINOBUTYRIC ACID receptor-ionophore complex. GABA-A receptors (RECEPTORS, GABA-A) appear to have at least three allosteric sites at which modulators act: a site at which BENZODIAZEPINES act by increasing the opening frequency of GAMMA-AMINOBUTYRIC ACID-activated chloride channels; a site at which BARBITURATES act to prolong the duration of channel opening; and a site at which some steroids may act. GENERAL ANESTHETICS probably act at least partly by potentiating GABAergic responses, but they are not included here.
Also Known As:
GABAergic Modulators; Acid Modulators, gamma-Aminobutyric; Modulators, GABA; Modulators, GABAergic; Modulators, gamma-Aminobutyric Acid; gamma Aminobutyric Acid Modulators; gamma-Aminobutyric Acid Modulators
Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Ghata, Adeline: 1 article (01/2014)
2. El-Khoury, Rita: 1 article (01/2014)
3. Matagne, Valérie: 1 article (01/2014)
4. Panayotis, Nicolas: 1 article (01/2014)
5. Roux, Jean-Christophe: 1 article (01/2014)
6. Villard, Laurent: 1 article (01/2014)
7. Bednar, Rodney A: 1 article (03/2012)
8. Coleman, Paul J: 1 article (03/2012)
9. Reiss, Duane R: 1 article (03/2012)
10. Breslin, Michael J: 1 article (03/2012)

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