|1.||Grando, Sergei A: 3 articles (10/2014 - 04/2006)|
|2.||Keyser, Kent T: 3 articles (05/2010 - 09/2005)|
|3.||Strang, Christianne E: 3 articles (05/2010 - 09/2005)|
|4.||Osman, Nadir I: 2 articles (04/2014 - 12/2013)|
|5.||Chapple, Christopher R: 2 articles (04/2014 - 12/2013)|
|6.||Sambeth, Anke: 2 articles (08/2013 - 02/2013)|
|7.||Klinkenberg, Inge: 2 articles (08/2013 - 02/2013)|
|8.||Blokland, Arjan: 2 articles (08/2013 - 02/2013)|
|9.||Sakakibara, Ryuji: 2 articles (01/2013 - 06/2006)|
|10.||Yamamoto, Tatsuya: 2 articles (01/2013 - 06/2006)|
|1.||Alzheimer Disease (Alzheimer's Disease)
07/01/2003 - "Alzheimer disease (AD) treatment guidelines state that cholinergic agents are not cost-effective in patients with more severe disease. "
05/01/2010 - "The synthesis and the AChE/BuChE inhibition studies are reported, confirming that compound 2 is a potent and selective AChE inhibitor, and consequently, a new lead compound for further development into new dual CAS/PAS cholinergic agents for the treatment of Alzheimer's disease."
02/01/2005 - "A few studies have suggested that cholinomimetics or AChE inhibitors can improve memory functions not only in Alzheimer's disease but also in other pathologies. "
01/01/2002 - "However, with the advent of new cholinergic agents now used for treating Alzheimer's disease, scope exists for more informative trials. "
01/01/1989 - "After a decade of intense study of cholinergic therapies for Alzheimer's disease, three conditions in this field are apparent: 1) The potential that cholinergic agents will ameliorate the memory dysfunction of Alzheimer patients (as 1-dopa benefits Parkinson patients) is still a stimulus for research. "
|2.||Movement Disorders (Movement Disorder)
01/01/2002 - "Cholinergic drugs did not result in any substantial improvement in tardive dyskinesia symptoms when compared with placebo (8 RCTs, 170 people, RR no important improvement 0.84 CI 0.68 to 1.04). "
11/01/2004 - "Systematic review of cholinergic drugs for neuroleptic-induced tardive dyskinesia: a meta-analysis of randomized controlled trials."
01/01/2002 - "If these new cholinergic agents are to be investigated for treating people with tardive dyskinesia, their effects should be demonstrated in well-designed, conducted and reported randomised trials."
11/01/2004 - "Further investigation of the clinical effects of novel cholinergic agents in tardive dyskinesia is warranted."
11/01/2004 - "Cholinergic drugs showed a minor trend for improvement of tardive dyskinesia symptoms, but results were not statistically significant (RR 0.84, 95% confidence interval (CI) 0.68 to 1.04, p=0.11). "
06/01/2015 - "In animal models, restoration of theta by sensory stimulation, septal electrical stimulation or cholinergic drugs infused into septum ameliorates seizures. "
01/01/2000 - "In 1983, we reported that intracerebral or systemic administration of cholinergic agents produced seizures and seizure-related brain damage in rodents. "
09/01/1999 - "Myoclonic and tonic seizures elicited by microinjection of cholinergic drugs into the inferior colliculus."
06/22/1990 - "None of the rats pretreated with saline had seizures when given doses of cholinomimetics alone. "
12/15/1983 - "Cholinomimetics produce seizures and brain damage in rats."
01/01/2015 - "BF cholinergic cell loss in dementia and the sedative effect of anti-cholinergic drugs have long implicated these neurons as important for cognition and wakefulness. "
01/01/2006 - "Widely used current treatments for dementia include extracts of Ginkgo biloba and several alkaloidal, and therefore toxic, plant-derived cholinergic agents. "
01/01/2006 - "Effects of cholinergic drugs and cognitive training on dementia: 2-year follow-up."
01/01/2004 - "Effects of cholinergic drugs and cognitive training on dementia."
04/01/1999 - "The effects of cholinergic drugs proposed for treatment of cognitive impairment in normal aging and dementia on divided attention have been little studied in non-human primates. "
|5.||Schizophrenia (Dementia Praecox)
05/21/2014 - "It has been shown that cholinergic system plays an important role in schizophrenia-associated cognitive deficits, therefore cholinergic drugs are novel targets for the treatment of cognitive deficits seen in schizophrenia. "
08/01/2013 - "Changes in auditory processing and sensory gating induced by cholinergic drugs may serve as a translational model for aging instead of schizophrenia. "
02/01/2013 - "It remains to be seen whether the effects of cholinergic drugs on AEPs are specifically related to the abnormalities found in schizophrenia. "
01/01/1979 - "Adrenergic and cholinergic drugs as episode and vulnerability markers of affective disorders and schizophrenia."
01/01/2015 - "Assessing the synergy between cholinomimetics and memantine as augmentation therapy in cognitive impairment in schizophrenia. "
|3.||Cholinesterase Inhibitors (Anticholinesterases)
|4.||Choline (Choline Chloride)
|8.||2- ethyl- 8- methyl- 2,8- diazaspiro(4,5)decane- 1,3- dione (RS 86)
|9.||Acetylcholine (Acetylcholine Chloride)
|10.||Cholinergic Antagonists (Anticholinergics)
|4.||Drug Therapy (Chemotherapy)