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Hypoplastic Left Heart Syndrome

A condition caused by underdevelopment of the whole left half of the heart. It is characterized by hypoplasia of the left cardiac chambers (HEART ATRIUM; HEART VENTRICLE), the AORTA, the AORTIC VALVE, and the MITRAL VALVE. Severe symptoms appear in early infancy when DUCTUS ARTERIOSUS closes.
Also Known As:
Left Heart Hypoplasia Syndrome; Left Heart Syndrome, Hypoplastic
Networked: 747 relevant articles (30 outcomes, 53 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Aortic Valve Stenosis (Aortic Stenosis)
2. Tricuspid Valve Insufficiency (Insufficiency, Tricuspid Valve)
3. Bronchitis
4. Tetralogy of Fallot (Fallot Tetralogy)
5. Pulmonary Atresia (Pulmonary Valve Atresia)

Experts

1. Mahle, William T: 14 articles (01/2016 - 02/2002)
2. Tweddell, James S: 12 articles (11/2013 - 09/2002)
3. Kramer, Hans-Heiner: 11 articles (01/2015 - 02/2010)
4. Ghanayem, Nancy S: 11 articles (11/2013 - 09/2002)
5. Gaynor, J William: 10 articles (04/2014 - 02/2002)
6. Scheewe, Jens: 10 articles (02/2014 - 05/2006)
7. Wernovsky, Gil: 9 articles (04/2014 - 01/2004)
8. Tworetzky, Wayne: 8 articles (08/2014 - 07/2004)
9. Spray, Thomas L: 8 articles (04/2014 - 02/2002)
10. Hoffman, George M: 8 articles (11/2013 - 09/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Hypoplastic Left Heart Syndrome:
1. PlasticsIBA
2. PhenoxybenzamineFDA Link
3. Carbon DioxideIBA
4. Dinoprostone (PGE2)FDA Link
5. Tissue Plasminogen Activator (Alteplase)FDA Link
6. Aprotinin (Trasylol)FDA Link
7. Coarctation of the aortaIBA
8. OxygenIBA
9. Pulmonary venous return anomalyIBA
10. 12- (4'- azido- 2'- nitrophenoxy)dodecanoyl- coenzyme AIBA

Therapies and Procedures

1. Norwood Procedures
2. Transplantation (Transplant Recipients)
3. Heart Transplantation (Grafting, Heart)
4. Fontan Procedure (Fontan Operation)
5. Blalock-Taussig Procedure