HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

PrPC Proteins

Normal cellular isoform of PRION PROTEINS encoded by a chromosomal gene and found in normal and scrapie-infected brain tissue, and other normal tissue. PrPC are protease-sensitive proteins whose function is unknown. Posttranslational modification of PrPC into PrPSC leads to infectivity.
Also Known As:
Cp 33-35; Cp33-35, Scrapie; PrP-sen; PrP sen; Scrapie Amyloid Precursor Protein
Networked: 38 relevant articles (0 outcomes, 4 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Priola, Suzette A: 7 articles (05/2009 - 09/2002)
2. Caughey, B: 6 articles (08/2002 - 05/2000)
3. Caughey, Byron: 5 articles (04/2012 - 03/2002)
4. Priola, S A: 5 articles (12/2001 - 05/2000)
5. Vorberg, Ina: 3 articles (07/2004 - 09/2002)
6. Xiong, L W: 3 articles (11/2001 - 02/2001)
7. Horiuchi, M: 3 articles (05/2001 - 05/2000)
8. Hughson, Andrew G: 2 articles (04/2012 - 08/2007)
9. Ward, Anne E: 2 articles (05/2009 - 09/2008)
10. Dorward, David W: 2 articles (08/2007 - 03/2002)

Related Diseases

1. Scrapie
2. Prion Diseases (Transmissible Spongiform Encephalopathies)
3. Neuroblastoma
4. Conversion Disorder (Astasia Abasia)
5. Infections

Related Drugs and Biologics

1. PrPSc Proteins
2. Peptide Hydrolases (Proteases)
3. Prion Proteins
4. Amino Acids
5. Protein Isoforms (Isoforms)
6. Endopeptidase K (Proteinase K)
7. Proteins (Proteins, Gene)
8. Glycoproteins (Glycoprotein)
9. Phosphoinositide Phospholipase C
10. Tetrapyrroles