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Multifetal Pregnancy Reduction

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Selective abortion of one or more embryos or fetuses in a multiple gestation pregnancy. The usual goal is to improve the outcome for the remaining embryos or fetuses.

Also Known As:

Pregnancy Reduction, Multifetal; Embryo Reductions; Fetal Reductions; Fetal Terminations, Selective; Multifetal Pregnancy Reductions; Pregnancy Reductions, Multifetal; Reduction, Embryo; Reduction, Fetal; Reduction, Multifetal Pregnancy; Reductions, Embryo; Reductions, Fetal; Reductions, Multifetal Pregnancy; Selective Fetal Termination; Selective Fetal Terminations; Termination, Selective Fetal; Terminations, Selective Fetal; Embryo Reduction; Fetal Reduction; Fetal Termination, Selective

Networked: 69 relevant articles (2 outcomes, 9 trials/studies) for this Therapy, Comments

Relationship Network

Therapy Context: Research Results

Operative Surgical Procedures: 5
- Obstetric Surgical Procedures: 58
  - Induced Abortion: 1322
    - Therapeutic Abortion: 374
      - Multifetal Pregnancy Reduction: 69
    - Multifetal Pregnancy Reduction: 69

Experts

1.	Evans, Mark I: 2 articles (09/2005 - 11/2002)
2.	Taşkin, Salih: 1 article (10/2009)
3.	Taşkin, Elif Aylin: 1 article (10/2009)
4.	Ciftçi, Turan Türkmen: 1 article (10/2009)
5.	Papagianni, Vassiliki: 1 article (07/2009)
6.	Makrakis, Evangelos: 1 article (07/2009)
7.	Deligeoroglou, Efthimios: 1 article (07/2009)
8.	Tsai, Horng-Der: 1 article (06/2009)
9.	Hsieh, Hsin-Chin: 1 article (06/2009)
10.	Chen, Tze-Ho: 1 article (06/2009)

Related Diseases

1.	Infertility (Sterility) 11/01/1995 - "As improved techniques of infertility treatment are yielding more high-order multiple gestations, multifetal pregnancy reduction is being performed more frequently. " 01/01/2003 - "While randomised controlled trials will provide the most reliable evidence about the risks and benefits of fetal reduction procedures, reduction in the number of fetuses by selective termination may not been acceptable to women, especially for those with a past history of infertility. " 06/01/1995 - "STUDY DESIGN: The methods of infertility treatment, number of fetuses, and outcomes of 220 patients referred for multifetal pregnancy reduction were compared over three time periods (1986 to 1989, 1991 to 1992, and 1992 to 1993). " 05/01/2009 - "OBJECTIVE: To report an unusual case of congenital cervical atresia and tubal factor infertility, achieving triplet pregnancy through transmyometrial embryo transfer (ET) resulting in the delivery of healthy twins after multifetal pregnancy reduction (MFPR). " 06/01/2007 - "Counseling for treatment of infertility should include a discussion of the risks of multifetal pregnancy, multifetal pregnancy reduction should be discussed with patients before the initiations of any treatment that could increase the risk of multifetal pregnancy. " Order ALL the reference details at left...
2.	Chromosome Aberrations (Chromosome Abnormalities) 12/01/2004 - "The safety and efficacy of transabdominal chorionic villus sampling and the higher pregnancy rate of chromosomal abnormalities in multiple pregnancies imply that fetal karyotyping should be advised before fetal reduction." 03/01/2001 - "Whereas FISH may provide rapid and useful assessment of fetal status in decision-making regarding fetal reduction, the present study also highlighted the obstetrical difficulty of ensuring a sample representative of each fetus following CVS in addition to the possibility of not identifying clinically significant chromosome aberrations using currently available FISH probes." 03/01/1996 - "OBJECTIVE: Our purpose was to assess the effect of multifetal pregnancy reduction on maternal serum levels of analytes used for screening low-risk women for fetal chromosome abnormalities and neural tube defects. " Order ALL the reference details at left...
3.	Birth Weight (Birth Weights) 09/01/2008 - "CONCLUSION: Our study showed the median birth weight, rates of pregnancy loss and prematurity after the fetal reduction procedure was comparable with other studies. " 07/01/1998 - "STUDY DESIGN: This retrospective cohort study investigated the rates of birth weight discordance > 20% and intrauterine growth restriction using both twin and singleton birth weight curves in 441 twin deliveries after multifetal pregnancy reduction (233 reduced from triplets, 156 from quadruplets, and 52 from quintuplets or greater) compared with 136 nonreduced dichorionic twins. " 07/01/2007 - "RESULT(S): The fetal reduction group was associated with a higher incidence of extreme prematurity, prematurity, and lower birth weight than the nonreduced group, although the impact was relatively small. " 02/01/2003 - "Embryo reduction is an independent risk factor for birth weight discordance in dichorionic twins. " 02/01/2003 - "In multivariate analysis, embryo reduction was the only significant risk factor for the occurrence of birth weight discordance [adjusted odds ratio (OR) = 2.3 (1.0-5.2)]. " Order ALL the reference details at left...
4.	Fetofetal Transfusion (Twin Transfusion Syndrome) 06/01/2001 - "This paper discusses a personal selection of controversial issues, such as multifetal pregnancy reduction of triplets and twins, special cases in multifetal pregnancy reduction, need for invasive genetic studies, management of twin-twin transfusion, discordant fetal conditions, the definition of "term" in multiples, and the controversy about the mode of delivery." 06/01/2006 - "Pregnancies complicated by twin-to-twin transfusion syndrome, monoamniotic twins, or lethal fetal anomalies, and those treated by fetal reduction were excluded. " 10/01/2005 - "This presents unique challenges for the performance of selective fetal termination in cases of twin-twin transfusion syndrome, twin reversed arterial perfusion sequence, or discordant twin abnormalities. " Order ALL the reference details at left...
5.	Chromosome Disorders (Chromosome Disorder) 04/01/1995 - "The rate of chromosomal disorders was higher (7.2%) in the study series than in singleton pregnancies not undergoing fetal reduction. " Order ALL the reference details at left...

Related Drugs and Biologics

1.	C-Reactive Protein
2.	Pyridinolcarbamate (P23)
3.	Potassium Chloride

Related Therapies and Procedures

1.	Cesarean Section (Caesarean Section)
2.	Laser Therapy (Surgery, Laser)
3.	Bed Rest (Bedrest)
4.	Induced Abortion (Induced Abortions)

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