Intrinsic Positive-Pressure Respiration
124
relevant articles (7 outcomes,
10 trials/studies)
found for this Disease
Description:
Non-therapeutic positive end-expiratory pressure occurring frequently in patients with severe airway obstruction. It can appear with or without the administration of external positive end-expiratory pressure (POSITIVE-PRESSURE RESPIRATION). It presents an important load on the inspiratory muscles which are operating at a mechanical disadvantage due to hyperinflation. Auto-PEEP may cause profound hypotension that should be treated by intravascular volume expansion, increasing the time for expiration, and/or changing from assist mode to intermittent mandatory ventilation mode. (From Harrison's Principles of Internal Medicine, 12th ed, p1127)
Also Known As:
Positive-Pressure Respiration, Intrinsic; AutoPEEP; Non-Therapeutic Positive-Pressure Respiration; Nontherapeutic Positive-Pressure Respiration; Positive-Pressure Respiration, Non-Therapeutic; Positive-Pressure Respiration, Nontherapeutic; Respiration, Non-Therapeutic Positive-Pressure; Respiration, Nontherapeutic Positive-Pressure; Auto PEEP; Intrinsic PEEP; Non Therapeutic Positive Pressure Respiration; Nontherapeutic Positive Pressure Respiration; Occult PEEP; Occult Positive-Pressure Respiration; Positive Pressure Respiration, Intrinsic; Positive Pressure Respiration, Non Therapeutic; Positive Pressure Respiration, Nontherapeutic; Positive Pressure Respiration, Occult; Respiration, Intrinsic Positive-Pressure; Respiration, Non Therapeutic Positive Pressure; Respiration, Nontherapeutic Positive Pressure; Respiration, Occult Positive-Pressure; Auto-PEEP; PEEP, Intrinsic; PEEP, Occult; Positive-Pressure Respiration, Occult
Relationship Network
Disease Context: Research Results
Related Diseases
Experts
| 1. | Brochard, Laurent:
1 article
(10/2002)
|
| 2. | Ducreux, J C:
1 article
(10/2002)
|
| 3. | Beuret, P:
1 article
(10/2002)
|
| 4. | Ducastelle, S:
1 article
(10/2002)
|
| 5. | Younes, M:
1 article
(11/2000)
|
| 6. | Polese, G:
1 article
(09/2000)
|
| 7. | Mergoni, M:
1 article
(09/2000)
|
| 8. | Cobelli, C:
1 article
(09/2000)
|
| 9. | Nucci, G:
1 article
(09/2000)
|
| 10. | Bricchi, C:
1 article
(09/2000)
|
Drugs and Biologics
Drugs and Important Biological Agents (IBA) related to Intrinsic Positive-Pressure Respiration:
| 1. | OxygenIBA
11/01/1999
- " Auto-PEEP levels and cardiac index should be monitored to ensure tissue oxygen delivery is maintained." 02/01/1990
- " The presence of intrinsic PEEP acts as an inspiratory threshold load, and contributes significantly to the observed increase in work and oxygen cost of breathing" 09/01/1993
- " In all modes, the inspiratory oxygen fraction, tidal volume, respiratory rate, and total positive end-expiratory pressure (PEEPt = applied PEEP + intrinsic PEEP) were kept constant" 11/01/2002
- " The paper presents the results of a study of the impact of autoPEEP (positive end-expiratory pressure) on gas exchange in the lungs, their biomechanical characteristics, the transport and consumption of oxygen by inverting the inspiration/expiration ratio under the volume-controlled mechanical ventilation of the lung (VCMVL) in patients with acute parenchymatous lung lesion, as well as how to choose the optimum inspiration/expiration ratio in VCMVL by analyzing the pattern of total PEEP (the sum of positioning and autoPEEP) in this group of patients." 11/01/1999
- " Within 24 hours of conversion to PCIRV, the patients stabilized and the mean PaO2:FiO2 ratio rose from 96.3+/-57.8 to 146.8+/-91.1 (P<0.05) and PIP fell from 47.9+/-13.8 to 38.8+/-8.4 cm H2O; auto-PEEP increased from 0.5+/-1.9 to 7.5+/-5.6 cm H2O (P<0.05); oxygen delivery index remained stable (563+/-152 to 497+/-175 mL/min/m2); three patients developed evidence of barotrauma, one patient developed critical illness polyneuropathy, and two patients died (13%)"
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| 2. | IsofluraneFDA LinkGeneric
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| 3. | FenoterolIBA
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| 4. | PS 5 (PS-5)IBA
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| 5. | Carbon MonoxideIBA
05/01/1997
- " We conclude that IRV at a ratio that results in a significant intrinsic PEEP does not improve Pa(O2), enhances CO2 elimination, decreases cardiac output (CO), and does not exert any time-dependent effect." 01/01/2000
- " It is critical to monitor the adverse effects (triggering, auto-PEEP [positive end expiratory pressure], air trapping, and patient comfort) created by the additional flow introduced into the ventilator circuit, while balancing the CO (2) clearance" 04/01/2002
- " Assuming that central venous pressure (CVP) and pulmonary artery occlusion pressure (PAOP) are adequate estimates of the volume of the systemic and pulmonary circulation respectively, the following decision tree is suggested: 1) make a working diagnosis based on the relationship between pressure (CVP and PAOP) and cardiac output or stroke volume (CO or SV); 2) consider conditions that may alter reliability of CVP and PAOP in estimate adequately circulating volumes such as abnormal pressure/volume relationship (compliance) of the RV or LV, increased intrathoracic pressure (PEEP, autoPEEP, intra-abdominal pressure), valvular heart disease (mitral stenosis); 3) look at the history; 4) separating RV and LV by reciprocal variations of CVP, PAOP and SV"
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| 6. | Albuterol (Salbutamol)FDA LinkGeneric
07/01/1991
- " No significant changes were observed in the breathing pattern, intrinsic PEEP or arterial blood gas measurements after albuterol, and peripheral cardiovascular effects were not significant" 09/01/2005
- " In 10 anesthetized, mechanically ventilated, and bronchodilator-responsive COPD patients exhibiting moderate intrinsic PEEP (PEEPi), we assessed respiratory system (rs) mechanics, hemodynamics, and gas exchange at (a) baseline (zero PEEPe [ZEEPe]), (b) 30 min after 5 mg of nebulized salbutamol administration (ZEEPe-S), (c) 30 min after setting PEEPe at baseline PEEPi level (PEEPe), and (d) 30 min after 5 mg of nebulized salbutamol administration with PEEPe maintained unchanged (PEEPe-S)"
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| 7. | Ipratropium (Ipratropium Bromide)FDA LinkGeneric
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| 8. | KetamineFDA LinkGeneric
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| 9. | Halothane (Fluothane)FDA Link
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| 10. | Carbon DioxideIBA
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Therapies and Procedures