Filtering Surgery

A surgical procedure used in treatment of glaucoma in which an opening is created through which aqueous fluid may pass from the anterior chamber into a sac created beneath the conjunctiva, thus lowering the pressure within the eye. (Hoffman, Pocket Glossary of Ophthalmologic Terminology, 1989)

Also Known As:

Networked: 1663 relevant articles (113 outcomes, 180 trials/studies)

Relationship Network

Therapy Context: Research Results

Experts

1.	Khaw, Peng T: 15 articles (01/2022 - 03/2002)
2.	Wong, Tina T: 14 articles (01/2022 - 02/2010)
3.	Stalmans, Ingeborg: 11 articles (10/2021 - 11/2009)
4.	Sherwood, Mark B: 11 articles (01/2021 - 02/2004)
5.	Crowston, Jonathan G: 10 articles (02/2021 - 02/2010)
6.	Moons, Lieve: 10 articles (11/2016 - 11/2009)
7.	Van Bergen, Tine: 10 articles (11/2016 - 11/2009)
8.	Agnifili, Luca: 9 articles (11/2022 - 06/2011)
9.	Vandewalle, Evelien: 9 articles (10/2021 - 11/2011)
10.	Baudouin, Christophe: 9 articles (09/2021 - 11/2002)

Related Diseases

1.	Glaucoma 09/01/2016 - "Ocular decompression retinopathy is a rare complication of filtering surgery in patients with glaucoma; however, the course is benign in most cases, with spontaneous resolution of bleedings and improvement of visual acuity." 01/01/2019 - "The present study found that the whole OS system objectively improved after completely successful glaucoma filtration surgery. " 02/01/2009 - "If glaucoma filtration surgery is required, there are generally good results. " 02/01/2009 - "The three eyes that had glaucoma filtration surgery had good outcomes. " 12/01/2004 - "Glaucoma filtration surgery in pseudophakic eyes significantly improved IOP and reduced glaucoma medication requirements while maintaining stability of vision. "
2.	Blister (Bulla) 09/01/2006 - "Needle revision of the filtering bleb is a simple and safe technique that offers good results even years after a filtering surgery had been performed. " 01/01/2019 - "We determined the efficacy of wider area bleb revision after filtering surgery using bleb knife with adjunctive MMC. " 01/01/2017 - "The majority of complications seen in filtering surgery are largely eliminated by the nonpenetrating and bleb-independent approach. " 01/01/2012 - "The majority of complications seen in filtering surgery are largely eliminated by the nonpenetrating and bleb-independent approach. " 07/30/2010 - "Efficacy of amniotic membrane-assisted bleb revision for elevated intraocular pressure after filtering surgery."
3.	Cicatrix (Scar) 01/01/2008 - "Inhibition of CTGF expression may be effective in preventing undesirable scar formation during healing following filtration surgery." 08/01/2006 - "Smad7 gene transfer modulates injury-induced wound healing of conjunctival tissue in mice, suggesting that this strategy may be effective in preventing excessive scarring following filtration surgery. " 03/02/2022 - "In summary, PVA@rGO-Ag/5-Fu has promising potential as an efficacious and safe anti-scarring agent for filtering surgery." 09/15/2021 - "However, failure of filtering surgery commonly results from scarring formation at the surgical site, in which fibroblast proliferation plays an essential role in the scarring process. " 01/01/2020 - "Numerous methods have been used to reduce such scarring after filtration surgery and animal models have been important in the development of such techniques. "
4.	Open-Angle Glaucoma (Glaucoma, Open Angle) 08/01/2002 - "In eyes with open-angle glaucoma, viscocanalostomy is less effective in reducing intraocular pressure than standard filtering surgery. " 12/01/1996 - "When intraocular pressure is used as a therapeutic end point, both filtration surgery and medical therapy appear to be equally effective in maintaining long-term visual function and a stable optic disk in chronic open-angle glaucoma." 12/01/2012 - "Thus, our prospective data do not support the procedure of IDK as 'the gold standard' for filtering surgery in patients with open-angle glaucoma." 08/01/2022 - "This study shows that filtering surgery can reduce the progression of VF in patients with open-angle glaucoma, especially those whose disease develops aggressively. " 01/01/2006 - "Retrospective non randomised study including 171 eyes (136 patients), mean age: 63.9 years) with medically uncontrolled open-angle glaucoma and without previous filtering surgery. "
5.	Neovascular Glaucoma 05/01/2005 - "Vitrectomy combined with filtering surgery is considered to be an effective treatment for neovascular glaucoma to maintain the visual function for a long period." 09/01/1988 - "The visual acuities remained within one line of their preoperative levels or improved in 31 (76%) of the 41 aphakic or pseudophakic eyes with non-neovascular glaucomas; 3 (30%) of the 10 phakic eyes with non-neovascular glaucomas after failed filtering surgery; 10 (67%) of the 15 eyes with neovascular glaucomas; and 9 (100%) of the 9 eyes with non-neovascular glaucomas in patients younger than 13 years of age on whom Snellen acuity was available.(ABSTRACT TRUNCATED AT 250 WORDS)" 10/01/2019 - "Postoperative neovascular glaucoma, in which it is difficult to obtain satisfactory results using conventional filtering surgery, is one of the most serious complications of vitrectomy. " 01/01/2012 - "Surgical treatment for neovascular glaucoma has evolved from cyclodestructive procedures to full-thickness filtration surgery, to trabeculectomy with antifibrosis drugs and glaucoma drainage implant surgery. " 05/01/2009 - "[Antiangiogenic treatment for neovascular glaucoma and after filtering surgery]."

Related Drugs and Biologics

1.	Mitomycin (Mitomycin-C)
2.	Bevacizumab (Avastin)
3.	Fluorouracil (Carac)
4.	Antimetabolites
5.	Hydrogels
6.	Cytarabine (Cytosar-U)
7.	Ranibizumab (Lucentis)
8.	Ophthalmic Solutions (Eye Drops)
9.	Cyclosporine (Ciclosporin)
10.	Vorinostat

Related Therapies and Procedures

1.	Trabeculectomy (Trabeculoplasty)
2.	Therapeutics
3.	Vitrectomy
4.	Intracameral Injection
5.	Transplantation