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Isochromosomes

Metacentric chromosomes produced during MEIOSIS or MITOSIS when the CENTROMERE splits transversely instead of longitudinally. The chromosomes produced by this abnormal division are one chromosome having the two long arms of the original chromosome, but no short arms, and the other chromosome consisting of the two short arms and no long arms. Each of these isochromosomes constitutes a simultaneous duplication and deletion.
Also Known As:
Isochromosome
Networked: 296 relevant articles (2 outcomes, 13 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Chromosome Aberrations (Chromosome Abnormalities)
2. Visceral Leishmaniasis (Kala Azar)
3. Trisomy (Trisomies)
4. Neoplasms (Cancer)
5. Turner Syndrome (Turner's Syndrome)

Experts

1. Krantz, Ian D: 5 articles (12/2014 - 05/2012)
2. Maserati, Emanuela: 5 articles (09/2010 - 04/2006)
3. Pressato, Barbara: 4 articles (09/2010 - 04/2006)
4. Valli, Roberto: 4 articles (09/2010 - 04/2006)
5. Chen, Chih-Ping: 3 articles (02/2015 - 01/2003)
6. Izumi, Kosuke: 3 articles (12/2014 - 12/2012)
7. Kaur, Maninder: 3 articles (12/2014 - 12/2012)
8. Kotzot, D: 3 articles (01/2011 - 08/2001)
9. Pasquali, Francesco: 3 articles (04/2009 - 04/2006)
10. Kuo, Yu-Ling: 2 articles (02/2015 - 02/2015)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Isochromosomes:
1. AntigensIBA
2. alemtuzumab (Campath)FDA Link
3. Genetic Markers (Genetic Marker)IBA
4. trisomy Chromosome 8IBA
5. Mosaic variegated aneuploidy syndromeIBA
6. DNA (Deoxyribonucleic Acid)IBA
7. Bromodeoxyuridine (BrdU)IBA
8. AutoantibodiesIBA
9. HormonesIBA
10. Fluorescent Dyes (Fluorescent Probes)IBA

Therapies and Procedures

1. Transplants (Transplant)
2. Aftercare (After-Treatment)
3. Crowns (Crown, Dental)
4. Estrogen Replacement Therapy
5. Ligation