|1.||Prochiantz, Alain: 3 articles (12/2015 - 06/2011)|
|2.||Joshi, Rajiv L: 2 articles (12/2015 - 06/2011)|
|3.||Moya, Kenneth L: 2 articles (01/2013 - 06/2011)|
|4.||Schmidt, Christian A: 2 articles (01/2009 - 01/2009)|
|5.||Nagel, Stefan: 2 articles (01/2009 - 01/2009)|
|6.||Grabarczyk, Piotr: 2 articles (01/2009 - 01/2009)|
|7.||Meyer, Corinna: 2 articles (01/2009 - 01/2009)|
|8.||Przybylski, Grzegorz K: 2 articles (01/2009 - 01/2009)|
|9.||Drexler, Hans G: 2 articles (01/2009 - 01/2009)|
|10.||Venturini, Letizia: 2 articles (01/2009 - 01/2009)|
10/01/1990 - "In this study, we examined the expression of homeobox proteins in human cancer. "
07/15/2013 - "As both HLX1 and HOXA9 are oncogenes implicated in leukemogenesis, we discuss the implications that the collaboration between Homeobox proteins and PRCs has for senescence and cancer."
10/27/2011 - "The three-amino-acid loop extension (TALE) class homeodomain proteins MEIS1 and PKNOX1 (PREP1) share the ability to interact with PBX and HOX family members and bind similar DNA sequences but appear to play opposing roles in tumor development. "
02/01/2010 - "Thus, the homeotic proteins, by participating directly in the function of DNA replication origins, may provide a direct link between the accurate regulation of DNA replication required by the morphogenetic program and the deregulation of this process typical of cancer."
02/01/2010 - "Furthermore, many homeotic proteins are actually proto-oncogenes, since different translocations involving their genes cause tumors, particularly in the hematopoietic system. "
01/12/2012 - "The clustered homeobox proteins play crucial roles in development, hematopoiesis, and leukemia, yet the targets they regulate and their mechanisms of action are poorly understood. "
10/01/2006 - "Workshop on homeodomain proteins, hematopoietic development and leukemias."
01/28/2004 - "Both genes also cooperate to induce leukemia in a mouse leukemia acceleration assay, which can be explained, in part, by their physical interaction with each other as well as the PBX family of homeodomain proteins. "
11/01/1997 - "Furthermore, the Hoxa-9 gene is frequently activated by viral integration in the same BXH-2 leukemias, suggesting a biological synergy between these two distinct classes of homeodomain proteins in causing malignant transformation. "
03/01/2007 - "Many such studies also document co-overexpression of homeodomain proteins of the Meis and Pbx families in poor prognosis leukemia. "
|3.||Precursor B-Cell Lymphoblastic Leukemia-Lymphoma (Leukemia, Pre B Cell)
10/01/2004 - "We previously demonstrated that the homeodomain proteins (myeloid ecotropic integration site 1 [MEIS1], Pbx-regulating protein 1 [PREP1], and pre-B-cell leukemia transcription factors [PBXs]) bind to the novel regulatory element tandem repeat of MEIS1 binding element [TME] and transactivate the rat PF4 promoter. "
04/16/2004 - "Pre-B cell leukemia transcription factors (PBXs) act as cofactors in the transcriptional regulation mediated by Homeobox proteins during embryonic development and cellular differentition. "
03/01/2010 - "Pre B cell leukemia homeobox 2 (PBX2), a member of PBX family, acts as a co-factor of homeobox proteins to regulate proliferation and differentiation of tumor cells. "
01/01/2012 - "The pre B-cell leukemia transcription factor 1 (Pbx1) genes belong to the three amino acid loop extension family of homeodomain proteins that form hetero-oligomeric complexes with other homeodomain transcription factors, thereby modulating target specificity, DNA binding affinity and transcriptional activity of their molecular associates. "
04/16/2004 - "Previous studies investigating the anti-viral mechanisms of several cyclin-dependent kinase inhibitors showed that the homeoproteins, pre B-cell leukemia transcription factor 1 (PBX1) and PBX-regulating protein-1 (PREP1), function as transcriptional activators of Moloney murine leukemia virus. "
|4.||Ovarian Neoplasms (Ovarian Cancer)
05/30/2015 - "In this study, we show that two homeoproteins, HOXB13 and ALX4, are associated with epithelial to mesenchymal transition (EMT) and invasion of ovarian cancer cells. "
01/01/2015 - "Growing evidence linking activation of TGF-β pathway by homeodomain proteins prompted us to look for the possible involvement of this signalling pathway in PITX2-mediated progression of ovarian cancer. "
11/01/2007 - "MEIS and PBX homeobox proteins in ovarian cancer."
|5.||Pancreatic Neoplasms (Pancreatic Cancer)
10/01/2009 - "Our study provides, for the first time, an overview of a HOX protein expression in a large series of normal and neoplastic tissue types, identifies pancreatic cancer as one of the most affected by the HOXD13 hoemoprotein and underlines the way homeoproteins can be associated to human cancerogenesis."
|1.||Transcription Factors (Transcription Factor)
|6.||Proteins (Proteins, Gene)
|8.||DNA (Deoxyribonucleic Acid)
|9.||Forkhead Transcription Factors (Forkhead Box Proteins)