|1.||Safe, Stephen: 15 articles (05/2015 - 06/2002)|
|2.||Lawrence, B Paige: 14 articles (12/2015 - 04/2004)|
|3.||Perdew, Gary H: 11 articles (06/2015 - 05/2008)|
|4.||Fujii-Kuriyama, Yoshiaki: 9 articles (08/2015 - 11/2002)|
|5.||Matsumura, Fumio: 9 articles (05/2015 - 01/2004)|
|6.||El-Kadi, Ayman O S: 9 articles (02/2012 - 09/2004)|
|7.||Gonzalez, Frank J: 9 articles (01/2011 - 01/2004)|
|8.||Safe, S: 9 articles (05/2001 - 04/2000)|
|9.||Vorderstrasse, Beth A: 8 articles (08/2015 - 04/2004)|
|10.||Machala, Miroslav: 8 articles (07/2015 - 04/2006)|
11/01/2002 - "This study shows that ICZ may possess tumor promoter activity down-regulating GJIC by mechanisms, which seem to include activation of the Ah receptor and/or Cyp1 activity. "
07/01/1988 - "In the studies reported here, we show that the in vivo generation of cytotoxic T lymphocytes (CTL) in response to allogeneic tumor challenge is sensitive to suppression by 3,4,5,3',4',5'-hexachlorobiphenyl[(345)2-HxCB], a poorly metabolized, toxic, Ah receptor-binding PCB isomer. "
10/01/2015 - "The adverse outcome pathway for rodent liver tumor promotion by sustained activation of the aryl hydrocarbon receptor."
01/01/2015 - "The expression of these CYPs is regulated by aryl hydrocarbon receptors (AHR), the cellular target of PAH, and an important player in various diseases including cancer. "
01/01/2015 - "The aryl hydrocarbon receptor (AhR) is a heterodimeric transcriptional regulator with pleiotropic functions in xenobiotic metabolism and detoxification, vascular development and cancer. "
|2.||Breast Neoplasms (Breast Cancer)
01/01/2015 - "Previous studies showed anti-metastatic roles of agonist-activated aryl hydrocarbon receptor (Ahr) in various breast cancer cell lines. "
02/01/2010 - "In the current study, we report that ligand activation of the aryl-hydrocarbon receptor (AhR) inhibits multiple aspects of the metastatic process in a panel of breast cancer cell lines that represent the major breast cancer subtypes. "
05/18/2015 - "Aryl Hydrocarbon Receptor Ligand 5F 203 Induces Oxidative Stress That Triggers DNA Damage in Human Breast Cancer Cells."
05/01/2015 - "The aryl hydrocarbon receptor (AhR) mediates resistance to apoptosis induced in breast cancer cells."
02/01/2015 - "A novel compound, NK150460, exhibits selective antitumor activity against breast cancer cell lines through activation of aryl hydrocarbon receptor."
12/15/2015 - "Aryl Hydrocarbon Receptor Protects Lungs from Cockroach Allergen-Induced Inflammation by Modulating Mesenchymal Stem Cells."
08/01/2015 - "Vehicular exhaust particles promote allergic airway inflammation through an aryl hydrocarbon receptor-notch signaling cascade."
07/01/2015 - "Aryl hydrocarbon receptor (AHR) is believed to control the chronic inflammation in the gut. "
06/02/2015 - "Activation of aryl hydrocarbon receptor (AhR) and Nrf2-mediated oxidative stress response were found to be the most prominent effects, while the p53-mediated DNA damage response and NF-κB-mediated response to inflammation were not significantly affected. "
01/01/2014 - "The aryl hydrocarbon receptor (AhR) has gradually emerged as a regulator of inflammation in the lung and other tissues. "
|4.||Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
01/01/2013 - "The aryl hydrocarbon receptor (AhR) has been attributed with anti-inflammatory effects in the development of pathological immune responses leading to experimental autoimmune encephalomyelitis (EAE) via the induction of regulatory T cells. "
11/30/2010 - "An endogenous aryl hydrocarbon receptor ligand acts on dendritic cells and T cells to suppress experimental autoimmune encephalomyelitis."
12/01/2007 - "Resveratrol (trans-3,5,4'-trihydroxystilbene) ameliorates experimental allergic encephalomyelitis, primarily via induction of apoptosis in T cells involving activation of aryl hydrocarbon receptor and estrogen receptor."
10/01/2013 - "The activation of aryl hydrocarbon receptor by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) alleviates inflammation in experimental autoimmune encephalomyelitis (EAE), the best available model of MS. Therefore, we predicted that TCDD could attenuate EAE by inducing miRNA(s) targeting inflammatory mediators. "
|5.||Hepatocellular Carcinoma (Hepatoma)
01/01/1990 - "In this study we compare the subunit composition of two forms of the dioxin receptor, sedimenting at approximately 9S and approximately 6S respectively, which are present in nuclear extract from wild-type Hepa 1c1c7 mouse hepatoma cells following treatment in vivo with dioxin. "
01/01/1988 - "In this study we used a rat hepatoma cell line, H4IIE, to investigate the effect of such substances on an enzyme system, aryl hydrocarbon hydroxylase (AHH), which is regulated via the TCDD receptor. "
03/04/2015 - "We examined the expression kinetics of some of the aryl hydrocarbon receptor (AhR)-regulated genes in LA1 variant cells compared to wild type (WT) Hepa-1 mouse hepatoma cell lines, and we investigated the stability of AhR protein as a key step in the function of this receptor. "
12/01/2013 - "The interleukin-6-type cytokine oncostatin M induces aryl hydrocarbon receptor expression in a STAT3-dependent manner in human HepG2 hepatoma cells."
06/01/2013 - "The aryl-hydrocarbon-receptor (AhR) reporter system was utilized to transport a dioxin-responsive-element (DRE) via an adenovirus vector into rat hepatoma (H4IIE) cells before each experiment; these DRE-H4IIE cells were utilized in the Ad-DR bioassay. "
|4.||Ethanol (Ethyl Alcohol)
|5.||Arachidonic Acid (Vitamin F)
|6.||Cytochrome P-450 CYP1A1 (CYP1A1)
|7.||Cytochrome P-450 Enzyme System (Cytochrome P450)
|9.||Transcription Factors (Transcription Factor)
|3.||Heterologous Transplantation (Xenotransplantation)
|5.||Drug Therapy (Chemotherapy)