Epithelioid and Spindle Cell Nevus (Spitz Nevus)

A benign compound nevus occurring most often in children before puberty, composed of spindle and epithelioid cells located mainly in the dermis, sometimes in association with large atypical cells and multinucleate cells, and having a close histopathological resemblance to malignant melanoma. The tumor presents as a smooth to slightly scaly, round to oval, raised, firm papule or nodule, ranging in color from pink-tan to purplish red, often with surface telangiectasia. (Dorland, 27th ed)
Also Known As:
Spitz Nevus; Nevus, Epithelioid and Spindle Cell; Nevus, Spitz; Nevus, Spindle Cell and Epithelioid
Networked: 29 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Neoplasms (Cancer)
2. Melanoma (Melanoma, Malignant)
3. Nevus (Nevi)
4. Blue Nevus
5. Pigmented Nevus (Melanocytic Nevus)


1. Hoang, Mai P: 2 articles (02/2005 - 10/2003)
2. Li, Wen: 1 article (05/2014)
3. Zhu, Cheng-Yao: 1 article (05/2014)
4. Liu, Zhen: 1 article (05/2014)
5. Li, Shun-Fan: 1 article (05/2014)
6. Fan, Yi-Ming: 1 article (05/2014)
7. Meyer, Rebecca: 1 article (02/2014)
8. Israel, Steven A: 1 article (02/2014)
9. Gaudi, Sudeep: 1 article (02/2014)
10. Yachik, Theodore R: 1 article (02/2014)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Epithelioid and Spindle Cell Nevus:
1. ParaffinIBA
2. Formaldehyde (Formol)FDA Link
3. S100 Proteins (S 100 Protein)IBA
4. DNA (Deoxyribonucleic Acid)IBA
5. Insulin (Novolin)FDA Link
6. Carrier Proteins (Binding Protein)IBA
7. Proliferating Cell Nuclear Antigen (PCNA)IBA
8. CyclinsIBA
9. Melanins (Melanin)IBA
10. tebufenozide (Mimic)IBA