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Hutchinson's Melanotic Freckle (Lentigo Maligna)

A cellular subtype of malignant melanoma. It is a pigmented lesion composed of melanocytes occurring on sun-exposed skin, usually the face and neck. The melanocytes are commonly multinucleated with a "starburst" appearance. It is considered by many to be the in situ phase of lentigo maligna melanoma.
Also Known As:
Lentigo Maligna; Freckle, Hutchinson's Melanotic; Freckles, Melanotic; Hutchinson Melanotic Freckle; Hutchinsons Melanotic Freckle; Lentigos, Malignant; Malignant Lentigo; Malignant Lentigos; Melanotic Freckle, Hutchinson's; Melanotic Freckles; Freckle, Melanotic; Lentigo, Malignant; Melanotic Freckle
Networked: 244 relevant articles (26 outcomes, 15 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Melanoma (Melanoma, Malignant)
2. Neoplasms (Cancer)
3. Melanosis (Freckles)
4. Hutchinson's Melanotic Freckle (Lentigo Maligna)
5. Bowen's Disease (Disease, Bowen)

Experts

1. Zembowicz, Artur: 3 articles (11/2014 - 11/2007)
2. Bowen, Glen M: 3 articles (05/2012 - 02/2008)
3. Hunger, Robert E: 2 articles (01/2016 - 07/2008)
4. Wolfe, Rory: 2 articles (01/2015 - 10/2011)
5. Kirtschig, Gudula: 2 articles (01/2015 - 06/2010)
6. Zippin, Jonathan H: 2 articles (12/2014 - 12/2012)
7. Lawrence, C M: 2 articles (08/2014 - 01/2008)
8. Guitera, P: 2 articles (06/2014 - 01/2014)
9. Scolyer, R A: 2 articles (06/2014 - 01/2014)
10. Fogarty, G B: 2 articles (06/2014 - 01/2014)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Hutchinson's Melanotic Freckle:
1. imiquimod (Aldara)FDA LinkGeneric
2. azelaic acid (Azelex)FDA Link
3. ParaffinIBA
4. krestin (PSK)IBA
5. Monophenol Monooxygenase (Tyrosinase)IBA
6. Dicarboxylic AcidsIBA
7. VimentinIBA
8. Monoclonal AntibodiesIBA
9. hypericinIBA
10. styrene-methylmethacrylate copolymerIBA

Therapies and Procedures

1. Aftercare (After-Treatment)
2. Mohs Surgery (Mohs' Micrographic Surgery)
3. Radiotherapy
4. Cryosurgery
5. Immunotherapy