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Epithelioid Hemangioendothelioma

A tumor of medium-to-large veins, composed of plump-to-spindled endothelial cells that bulge into vascular spaces in a tombstone-like fashion. These tumors are thought to have "borderline" aggression, where one-third develop local recurrences, but only rarely metastasize. It is unclear whether the epithelioid hemangioendothelioma is truly neoplastic or an exuberant tissue reaction, nor is it clear if this is equivalent to Kimura's disease (see ANGIOLYMPHOID HYPERPLASIA WITH EOSINOPHILIA). (Segen, Dictionary of Modern Medicine, 1992)
Also Known As:
Hemangioendothelioma, Epithelioid; Epithelioid Hemangioendotheliomas; Hemangioendotheliomas, Epithelioid
Networked: 148 relevant articles (7 outcomes, 10 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Hemangiosarcoma (Angiosarcoma)
2. Neoplasm Metastasis (Metastasis)
3. Neoplasms (Cancer)
4. Hemangioma (Angioma)
5. Hepatocellular Carcinoma (Hepatoma)

Experts

1. Blay, Jean-Yves: 2 articles (01/2015 - 09/2014)
2. Chevreau, Christine: 2 articles (09/2014 - 07/2013)
3. Penel, Nicolas: 2 articles (09/2014 - 07/2013)
4. Fournier, Charles: 2 articles (09/2014 - 07/2013)
5. Le Cesne, Axel: 2 articles (09/2014 - 07/2013)
6. Bay, Jacques-Olivier: 2 articles (09/2014 - 07/2013)
7. Italiano, Antoine: 2 articles (09/2014 - 07/2013)
8. Bompas, Emmanuelle: 2 articles (09/2014 - 07/2013)
9. Ray-Coquard, Isabelle: 2 articles (09/2014 - 07/2013)
10. Clisant, Stéphanie: 2 articles (09/2014 - 07/2013)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Epithelioid Hemangioendothelioma:
1. bevacizumabFDA Link
2. sunitinib (Sutent)FDA Link
3. Interferon Alfa-2a (Interferon Alfa 2a)FDA Link
4. sorafenib (BAY 43-9006)FDA Link
5. Intrahepatic cholangiocarcinomaIBA
6. Kaposiform HemangioendotheliomaIBA
7. Fibrolamellar hepatocellular carcinomaIBA
8. DNA (Deoxyribonucleic Acid)IBA
9. VimentinIBA
10. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA

Therapies and Procedures

1. Liver Transplantation
2. Transplantation (Transplant Recipients)
3. Breast Implants (Breast Implant)
4. Orthoptics (Orthoptic)
5. Curettage