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Subependymal Glioma (Subependymoma)

Rare, slow-growing, benign intraventricular tumors, often asymptomatic and discovered incidentally. The tumors are classified histologically as ependymomas and demonstrate a proliferation of subependymal fibrillary astrocytes among the ependymal tumor cells. (From Clin Neurol Neurosurg 1997 Feb;99(1):17-22)
Also Known As:
Subependymoma; Glioma, Subependymal; Subependymal Astrocytoma; Subependymal Astrocytoma, Adult; Subependymal Gliosis; Adult Subependymal Astrocytoma; Adult Subependymal Astrocytomas; Astrocytoma, Adult Subependymal; Astrocytoma, Subependymal; Astrocytomas, Adult Subependymal; Astrocytomas, Subependymal; Gliomas, Subependymal; Glioses, Subependymal; Gliosis, Subependymal; Subependymal Astrocytomas; Subependymal Astrocytomas, Adult; Subependymal Gliomas; Subependymal Glioses; Subependymomas
Networked: 49 relevant articles (0 outcomes, 3 trials/studies)

Disease Context: Research Results

Related Diseases

1. Ependymoma
2. Neoplasms (Cancer)
3. Astrocytoma (Pilocytic Astrocytoma)
4. Neurocytoma
5. Meningioma (Meningiomas)

Experts

1. Park, Sung-Hye: 2 articles (03/2018 - 08/2005)
2. Jung, Hee-Won: 2 articles (08/2005 - 01/2003)
3. Kim, Dong Gyu: 2 articles (08/2005 - 01/2003)
4. Paek, Sun Ha: 2 articles (08/2005 - 01/2003)
5. Hunn, Martin: 1 article (03/2022)
6. Kweh, Barry Ting Sheen: 1 article (03/2022)
7. Rosenfeld, Jeffrey Victor: 1 article (03/2022)
8. Tee, Jin Wee: 1 article (03/2022)
9. Demetriades, Andreas K: 1 article (01/2021)
10. Kealey, Susan: 1 article (01/2021)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Subependymal Glioma:
1. Monoclonal AntibodiesIBA
2. Aquaporins (Water Channels)IBA
3. Biomarkers (Surrogate Marker)IBA
4. RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
5. StreptavidinIBA
01/01/1994 - "Paraffin-embedded surgical specimens from 136 primary human central nervous system (CNS) tumors, including 50 meningiomas, 24 astrocytomas, 26 anaplastic astrocytomas, 9 glioblastomas, 8 oligodendrogliomas, 4 ependymomas, 1 anaplastic ependymoma, 2 subependymomas, 9 medulloblastomas, and 3 paragangliomas, were immunostained, following microwave processing, using a streptavidin/peroxidase method and the MIB 1 monoclonal antibody (mAb) against the Ki-67 antigen. "
01/01/1993 - "Formalin-fixed, paraffin-embedded surgical specimens from 137 primary central nervous system tumors, including 26 astrocytomas (21 fibrillary, 1 protoplasmic, 1 gemistocytic and 3 pilocytic), 26 anaplastic astrocytomas, 9 glioblastomas, 1 gliosarcoma, 8 oligodendrogliomas, 4 ependymomas, 1 anaplastic ependymoma, 2 subependymomas, 3 paragangliomas, and 57 meningiomas, were immunostained with the CM1 polyclonal (pAb) and the DO-7 monoclonal (mAb) antibodies against the p53 protein, using the streptavidin/peroxidase method. "
01/01/1993 - "Formalin-fixed, paraffin-embedded surgical specimens from 140 primary human central nervous system tumors, including 51 meningiomas, 26 astrocytomas, 26 anaplastic astrocytomas, 9 glioblastomas, 1 gliosarcoma, 8 oligodendrogliomas, 5 ependymomas, 2 subependymomas, 9 medulloblastomas, and 3 paragangliomas, were immunostained using a streptavidin/peroxidase method and the PC10 monoclonal antibody, which recognizes an epitope on the proliferating cell nuclear antigen (PCNA). "
6. Proteins (Proteins, Gene)FDA Link
7. ParaffinIBA
01/01/1994 - "Paraffin-embedded surgical specimens from 136 primary human central nervous system (CNS) tumors, including 50 meningiomas, 24 astrocytomas, 26 anaplastic astrocytomas, 9 glioblastomas, 8 oligodendrogliomas, 4 ependymomas, 1 anaplastic ependymoma, 2 subependymomas, 9 medulloblastomas, and 3 paragangliomas, were immunostained, following microwave processing, using a streptavidin/peroxidase method and the MIB 1 monoclonal antibody (mAb) against the Ki-67 antigen. "
01/01/1993 - "Formalin-fixed, paraffin-embedded surgical specimens from 137 primary central nervous system tumors, including 26 astrocytomas (21 fibrillary, 1 protoplasmic, 1 gemistocytic and 3 pilocytic), 26 anaplastic astrocytomas, 9 glioblastomas, 1 gliosarcoma, 8 oligodendrogliomas, 4 ependymomas, 1 anaplastic ependymoma, 2 subependymomas, 3 paragangliomas, and 57 meningiomas, were immunostained with the CM1 polyclonal (pAb) and the DO-7 monoclonal (mAb) antibodies against the p53 protein, using the streptavidin/peroxidase method. "
01/01/1993 - "Formalin-fixed, paraffin-embedded surgical specimens from 140 primary human central nervous system tumors, including 51 meningiomas, 26 astrocytomas, 26 anaplastic astrocytomas, 9 glioblastomas, 1 gliosarcoma, 8 oligodendrogliomas, 5 ependymomas, 2 subependymomas, 9 medulloblastomas, and 3 paragangliomas, were immunostained using a streptavidin/peroxidase method and the PC10 monoclonal antibody, which recognizes an epitope on the proliferating cell nuclear antigen (PCNA). "
8. Peroxidase (Myeloperoxidase)IBA
01/01/1994 - "Paraffin-embedded surgical specimens from 136 primary human central nervous system (CNS) tumors, including 50 meningiomas, 24 astrocytomas, 26 anaplastic astrocytomas, 9 glioblastomas, 8 oligodendrogliomas, 4 ependymomas, 1 anaplastic ependymoma, 2 subependymomas, 9 medulloblastomas, and 3 paragangliomas, were immunostained, following microwave processing, using a streptavidin/peroxidase method and the MIB 1 monoclonal antibody (mAb) against the Ki-67 antigen. "
01/01/1993 - "Formalin-fixed, paraffin-embedded surgical specimens from 137 primary central nervous system tumors, including 26 astrocytomas (21 fibrillary, 1 protoplasmic, 1 gemistocytic and 3 pilocytic), 26 anaplastic astrocytomas, 9 glioblastomas, 1 gliosarcoma, 8 oligodendrogliomas, 4 ependymomas, 1 anaplastic ependymoma, 2 subependymomas, 3 paragangliomas, and 57 meningiomas, were immunostained with the CM1 polyclonal (pAb) and the DO-7 monoclonal (mAb) antibodies against the p53 protein, using the streptavidin/peroxidase method. "
01/01/1993 - "Formalin-fixed, paraffin-embedded surgical specimens from 140 primary human central nervous system tumors, including 51 meningiomas, 26 astrocytomas, 26 anaplastic astrocytomas, 9 glioblastomas, 1 gliosarcoma, 8 oligodendrogliomas, 5 ependymomas, 2 subependymomas, 9 medulloblastomas, and 3 paragangliomas, were immunostained using a streptavidin/peroxidase method and the PC10 monoclonal antibody, which recognizes an epitope on the proliferating cell nuclear antigen (PCNA). "
9. Formaldehyde (Formol)FDA Link
10. Protons (Proton)IBA

Therapies and Procedures

1. Radiotherapy
2. Therapeutics
3. Laminectomy
4. Craniotomy
5. Laminoplasty