Ganglioglioma
124
relevant articles (1 outcomes,
14 trials/studies)
found for this Disease
Description:
Rare indolent tumors comprised of neoplastic glial and neuronal cells which occur primarily in children and young adults. Benign lesions tend to be associated with long survival unless the tumor degenerates into a histologically malignant form. They tend to occur in the optic nerve and white matter of the brain and spinal cord.
Also Known As:
Ganglioglioma, Benign; Ganglioglioma, Intracranial; Ganglioglioma, Malignant; Benign Ganglioglioma; Benign Gangliogliomas; Gangliogliomas; Gangliogliomas, Benign; Gangliogliomas, Intracranial; Gangliogliomas, Malignant; Intracranial Ganglioglioma; Intracranial Gangliogliomas; Malignant Ganglioglioma; Malignant Gangliogliomas
Relationship Network
Disease Context: Research Results
Related Diseases
Experts
| 1. | Nasi, M T:
1 article
(11/2006)
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| 2. | Frattarelli, M:
1 article
(11/2006)
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| 3. | Paioli, G:
1 article
(11/2006)
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| 4. | Guiducci, G:
1 article
(11/2006)
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| 5. | Cultrera, F:
1 article
(11/2006)
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| 6. | Rumbolt, Zoran:
1 article
(11/2005)
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| 7. | Maria, Bernard L:
1 article
(11/2005)
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| 8. | Knapp, John:
1 article
(11/2005)
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| 9. | Tye, Sandra:
1 article
(11/2005)
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| 10. | Olson, Lori:
1 article
(11/2005)
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Drugs and Biologics
Drugs and Important Biological Agents (IBA) related to Ganglioglioma:
| 1. | Biological Tumor Markers (Tumor Markers)IBA
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| 2. | 2,6-dinitrotoluene (DNT)IBA
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| 3. | DNA (Deoxyribonucleic Acid)IBA
09/01/1988
- " This study describes the flow cytometric deoxyribonucleic acid (DNA) analysis of a resected ganglioglioma" 08/01/2002
- " In the present study the clinical data, histology, proliferation rate, DNA ploidy status and the results of TP53 mutation analysis and comparative genomic hybridization (CGH) of three typical cases of desmoplastic infantile astrocytoma and ganglioglioma are presented" 06/01/2004
- " DNA sequence analysis was carried out in gangliogliomas obtained from 29 epilepsy patients vs. peripheral blood DNA from non-affected control individuals (n = 100)" 04/01/2002
- " The only DNA copy number change found in two tumours (both cerebral GCT) was loss of 13q21, while the other nine aberrations were only encountered once each: the granular cells of one cerebral GCT additionally showed +1p32-pter, +9q33-qter, +20q, -4, and -18q, of the glioblastoma +7 and -10, and of the meningioma -1p and -22q, while the pituitary GCT, the ganglioglioma and the neurinoma showed no imbalances"
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| 4. | SynaptophysinIBA
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| 5. | ParaffinIBA
06/01/1999
- " This study retrospectively evaluates bcl-2 and bcl-x immunostaining in paraffin-embedded materials in gangliogliomas" 10/01/2003
- " The postoperative paraffin section and immunohistochemistry showed ganglioglioma, GFAP(+), CK(-), NF(+)" 03/01/2006
- " METHODS AND RESULTS: Anti-NeuN immunohistochemistry was performed on paraffin-embedded biopsy specimens of 106 diffuse astrocytomas, 100 pilocytic astrocytomas, 107 ependymomas, 59 1p-aberrant oligodendroglial neoplasms, 115 glioblastomas, 115 medulloblastomas, 14 gangliogliomas/gangliocytomas and 10 central neurocytomas" 05/01/1995
- " Formalin-fixed, paraffin-embedded sections from autopsy cases of AD, Down's syndrome with dementia and AD pathology (DS/AD), Pick's disease (PiD), progressive supranuclear palsy (PSP), Lewy body disease (LBD), Parkinson's disease (PD), corticobasal degeneration (CBD), and young and aged normal brains, and from two surgically resected gangliogliomas were immunostained using antibodies to Ki-67 (MIB-1 clone equivalent) and tau (tau)" 11/01/2000
- " A temporal lobe ganglioglioma, surgically removed from an 8-year-old body, and a human brainstem at the level of locus coeruleus (LC) were processed for light microscopy (LM), with formalin fixation and paraffin embedding, and for electron microscopy (EM) with glutaraldehyde fixation, potassium permanganate postfixation, phosphotungstic acid-hematoxylin block-staining, and epoxy resin embedding"
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| 6. | Messenger RNA (mRNA)IBA
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| 7. | AntigensIBA
03/01/2002
- " Our goal was to characterize the expression of nestin, a neuroepithelial precursor/stem cell antigen, in gangliogliomas along with other pathological and clinical features of this entity" 10/15/1987
- " No S-antigen and opsin-like immunoreaction was found in malignant teratomas and germinomas of the pineal gland, oat cell tumors, astrocytomas, ependymomas, oligodendrogliomas, glioblastomas, gangliogliomas, gangliocytoma, ganglioneuroblastomas, neuroblastomas, and esthesioneuroblastoma." 06/01/2005
- " In the present study, the distribution of cells of the microglia/macrophage lineage was studied by immunocytochemistry for CD68 and human leucocyte antigen (HLA)-DR in a group of glioneuronal tumours, including gangliogliomas (GG, n = 30), and dysembryoplastic neuroepithelial tumours (DNT, n = 17), from patients with chronic intractable epilepsy"
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| 8. | Androgen Receptors (Androgen Receptor)IBA
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| 9. | CollagenIBA
01/01/1992
- " Beside these two typical components for ganglioglioma, an abundance of collagen fibrils and numerous blood vessels were encountered" 12/01/1996
- " These findings suggests that collagen IV and laminin and perivascular inflammation are related to the indolent behavior of gangliogliomas." 12/01/1996
- " Significant deposition of collagen IV and laminin was found in 9 gangliogliomas (47%), but in none of the other gliomas" 12/01/1996
- " We also examined whether the presence of collagen IV and laminin correlated with other features often observed in gangliogliomas, including perivascular lymphocytic inflammation, granular bodies, microcalcification, and subarachnoid extension, and whether any of these features were associated with the patient's clinical course" 12/01/1996
- " Our study compared the relative presence and deposition pattern of collagen IV and laminin in 19 gangliogliomas and in 18 gliomas without ganglion cell differentiation (8 low-grade astrocytomas, 7 anaplastic astrocytomas, and 3 anaplastic mixed gliomas)"
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| 10. | N 30IBA
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| 99 Drugs and Important Bio-Agents
and
115
more articles analyzed in the Research Interface, order at left...
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Therapies and Procedures
| 1. | Drug Therapy (Chemotherapy)
12/01/2006
- " Only 3% of gangliogliomas occur in the brain stem, and its management can be challenging because of the difficulty of radical resection and poor response to both radiotherapy and chemotherapy." 02/01/2007
- " However, the posterior temporal lesion was identified as a malignant ganglioglioma/glioblastoma multiforme variant that recurred multiple times requiring several surgeries, radiation and chemotherapy" 12/01/2006
- " The histological diagnosis was ganglioglioma, WHO grade 2. Although both radiotherapy and chemotherapy were performed following the operation, the tumor remained unchanged" 12/01/2003
- " Based on the above findings, irrespective of radiotherapy or chemotherapy, rare recurrence of malignant evolution, especially tumors of high S-phase fraction on flow cytometry, warrants long-term follow-up, even in a well-differentiated ganglioglioma." 12/01/2003
- " This is the first report of a genetic alteration in glioblastoma arising from a well differentiated ganglioglioma prior to radiation or chemotherapy"
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| 2. | Ventriculoperitoneal Shunt
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| 3. | Ventriculostomy
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| 4. | Decompression
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| 5. | Craniotomy
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| 6 Therapies and Procedures
and
12
more articles analyzed in the Research Interface, order at left...
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