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Basal Cell Neoplasms (Basal Cell Cancer)

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Neoplasms composed of cells from the deepest layer of the epidermis. The concept does not refer to neoplasms located in the stratum basale.

Also Known As:

Basal Cell Cancer; Neoplasms, Basal Cell; Basal Cell Cancers; Basal Cell Neoplasm; Cancer, Basal Cell; Cancers, Basal Cell; Cell Cancer, Basal; Cell Cancers, Basal; Cell Neoplasm, Basal; Cell Neoplasms, Basal; Neoplasm, Basal Cell

Networked: 36 relevant articles (2 outcomes, 8 trials/studies) for this Disease, Comments

Relationship Network

Disease Context: Research Results

Neoplasms: 421329
- Neoplasms by Histologic Type: 1
  - Glandular and Epithelial Neoplasms: 257
    - Basal Cell Neoplasms: 36

Related Diseases

1.	Squamous Cell Neoplasms (Squamous Cell Cancer)
2.	Melanoma (Melanoma, Malignant)
3.	Residual Neoplasm
4.	Skin Neoplasms (Skin Cancer)
5.	Papilloma (Papillomatosis)

Experts

1.	Rudin, Charles M: 1 article (01/2010)
2.	Diffey, Brian: 1 article (10/2009)
3.	Kumarasinghe, Prasad: 1 article (02/2009)
4.	Cherian, Paul: 1 article (02/2009)
5.	Simka, Marian: 1 article (05/2008)
6.	Shindel, Alan W: 1 article (11/2007)
7.	Sengelmann, Roberta: 1 article (11/2007)
8.	Petersen, Jeffrey: 1 article (11/2007)
9.	Mann, Margaret W: 1 article (11/2007)
10.	Lev, Ronan Y: 1 article (11/2007)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Basal Cell Neoplasms:

1.	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 01/01/2010 - "This new study of cyclooxygenase inhibition, together with recent data on the efficacy of hedgehog pathway inhibition, offers new hope for patients at a high risk for basal cell cancer." Order ALL the reference details at left...
2.	Sunscreening Agents (Sunscreens)IBA 10/01/2009 - "Sunscreens have been shown to be effective in reducing the incidence of squamous cell cancer and with promising benefits for basal cell cancer. " Order ALL the reference details at left...
3.	CarcinogensIBA 12/15/1988 - "Although this study is essentially descriptive, accurate inspection of these data provides some support for the major aetiological hypotheses of skin carcinogenesis, i.e., the observation that the large majority of basal- and squamous-cell cancers arise on the head and neck confirms the importance of long-term ultraviolet exposure; the relative excess of squamous-cell as compared to basal-cell neoplasms on the upper limb may suggest the role of exposure to other (chemical) carcinogens; and the proportional excess of melanomas on the trunk in males and lower limb in females further indicates that intermittent exposure to sunlight is probably the relevant aetiologic factor for melanocytic skin neoplasms." 09/02/1998 - "To assess the persistence of cancer risk among individuals treated with PUVA, including those who discontinued therapy long ago and those without substantial exposure to other carcinogens, we prospectively studied a cohort of 1380 patients with psoriasis who were first treated during the period from January 1, 1975, through October 1, 1976, and evaluated risk factors associated with the development of cutaneous squamous cell cancers and basal cell cancers after 1985. " Order ALL the reference details at left...
4.	Monoclonal AntibodiesIBA 02/01/2004 - "A series of 9 cases of squamous cell cancer (SCC), 15 cases of basal cell cancer (BCC) and 43 cases of squamous cell papilloma (SCP) were assessed using the immunohistochemical method with monoclonal antibodies. " 01/01/1991 - "[Laminin and heparan sulfate proteoglycan of the basal membrane in basal cell cancer (an immunohistochemical study using monoclonal antibodies)]" Order ALL the reference details at left...
5.	Heparan Sulfate Proteoglycans (Heparan Sulfate Proteoglycan)IBA 01/01/1991 - "[Laminin and heparan sulfate proteoglycan of the basal membrane in basal cell cancer (an immunohistochemical study using monoclonal antibodies)]" Order ALL the reference details at left...
6.	Proliferating Cell Nuclear Antigen (PCNA)IBA 02/01/2004 - "The aim of our study was an evaluation of the expression of cell proliferation markers (PCNA and Ki-67) in conjunctival and eyelid papillomas and squamous and basal cell cancers. " Order ALL the reference details at left...
7.	Vitamin E FDA Link 07/01/2005 - "This article reviews human studies of basal cell cancer (BCC) and squamous cell cancer (SCC) and includes all studies identified in the published scientific literature investigating dietary exposure to fats, retinol, carotenoids, vitamin E, vitamin C, and selenium. " Order ALL the reference details at left...
8.	Vitamin A (Retinol)FDA Link 07/01/2005 - "This article reviews human studies of basal cell cancer (BCC) and squamous cell cancer (SCC) and includes all studies identified in the published scientific literature investigating dietary exposure to fats, retinol, carotenoids, vitamin E, vitamin C, and selenium. " Order ALL the reference details at left...
9.	SeleniumIBA 07/01/2005 - "This article reviews human studies of basal cell cancer (BCC) and squamous cell cancer (SCC) and includes all studies identified in the published scientific literature investigating dietary exposure to fats, retinol, carotenoids, vitamin E, vitamin C, and selenium. " Order ALL the reference details at left...
10.	Laminin (Merosin)IBA 01/01/1991 - "[Laminin and heparan sulfate proteoglycan of the basal membrane in basal cell cancer (an immunohistochemical study using monoclonal antibodies)]" Order ALL the reference details at left...

Therapies and Procedures

1.	Photochemotherapy (Photodynamic Therapy) 01/01/1999 - "STUDY DESIGN/MATERIALS AND METHODS: In a prospective clinical trial the effect of photodynamic therapy on primary nonmelanomatous skin tumours of the head and neck (basal cell cancer, squamous cell cancer) was tested. " Order ALL the reference details at left...
2.	Lasers (Laser) 09/01/1997 - "Genomic analysis of single cells from human basal cell cancer using laser-assisted capture microscopy." 08/29/2002 - "In the article we give one example on how we have used the PALM laser microscopy system in combination with a nested, multiplex PCR system to analyze single normal keratinocytes as well as tumor cells from a case of basal cell cancer. " 09/01/1999 - "BACKGROUND: With the development of the short-pulse CO2 laser it was hoped that this resurfacing would prevent recurrent actinic keratoses and basal cell cancers similar to resurfacing with dermabrasion, laser abrasion, and deep chemical peel. " 11/01/1997 - "UV induced erythema evaluated 24 h post-exposure by skin reflectance and laser Doppler flowmetry is identical in healthy persons and patients with cutaneous malignant melanoma and basal cell cancer." Order ALL the reference details at left...
3.	Transplantation (Transplant Recipients) 05/15/2008 - "There is one well-documented case of basal cell cancer which has arisen from donor cells in a kidney transplant recipient, but it remains unclear if this cancer developed directly from a donor-derived cell, or via fusion of such cells with premalignant keratinocytes. " 03/01/2005 - "RESULTS: Transplant recipients from the United States with skin malignancies were identified (n = 2018) and assigned to 1 of 3 groups: squamous cell cancer (SCC), basal cell cancer (BCC), or combined malignancies (BCC/SCC). " Order ALL the reference details at left...
4.	Gas Lasers 09/01/1999 - "OBJECTIVE: To document the problems of recurrent keratoses and basal cell cancers in patients following CO2 laser resurfacing. " 09/01/1999 - "CONCLUSION: CO2 laser resurfacing is not as effective as dermabrasion, chemabrasion, and deep chemical peel for the prophylaxis of actinic keratoses and basal cell cancers, especially in Fitzpatrick type I and II patients." 09/01/1999 - "BACKGROUND: With the development of the short-pulse CO2 laser it was hoped that this resurfacing would prevent recurrent actinic keratoses and basal cell cancers similar to resurfacing with dermabrasion, laser abrasion, and deep chemical peel. " Order ALL the reference details at left...
5.	Quantum Dots (Quantum Dot) 05/01/2006 - "The invention of quantum dots and their biomedical applications make them as good markers for tumor cell tracing and targeting in cancer research, such as prostate cancer, mammary cancer, cervical cancer, basal cell carcinoma, liver cancer, and melanoma. " Order ALL the reference details at left...

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